Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog

scientific article published on February 1999

Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.19.2.1049
P932PMC publication ID116035
P698PubMed publication ID9891040

P2093author name stringH Endoh
S Kato
H Fuse
J Yanagisawa
K Takeyama
S Kitanaka
A Murayama
M Suzawa
Y Masuhiro
P2860cites workCloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cellsQ24314557
The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathwaysQ24320338
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptorQ24323091
Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptorsQ24324051
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300Q24324556
Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptorQ24532913
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptorsQ24562254
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1Q24563324
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptorsQ24600501
A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free systemQ24601592
Molecular basis of agonism and antagonism in the oestrogen receptorQ27746278
Sequence and characterization of a coactivator for the steroid hormone receptor superfamilyQ27860465
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptorsQ27860552
The nuclear receptor superfamily: the second decadeQ27860725
SH2 domains recognize specific phosphopeptide sequencesQ27860748
The transcriptional coactivators p300 and CBP are histone acetyltransferasesQ27860843
A signature motif in transcriptional co-activators mediates binding to nuclear receptorsQ27860938
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancerQ28245902
25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesisQ28248764
Steroid receptor coactivator-1 is a histone acetyltransferaseQ28248899
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcriptionQ28254487
A Novel Vitamin D3Analog, 22-Oxa-1, 25- Dihydroxyvitamin D3, Inhibits the Growth of Human Breast Cancerin Vitroandin Vivowithout Causing Hypercalcemia*Q28327218
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaningQ28508915
Correlation of two-hybrid affinity data with in vitro measurementsQ29615774
Role of CBP/P300 in nuclear receptor signallingQ29616443
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinaseQ29617567
Steroid hormone receptors: many actors in search of a plotQ29618397
Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) geneQ34460757
Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors.Q36555582
Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activityQ37638476
Intron retention generates a novel isoform of the murine vitamin D receptor that acts in a dominant negative way on the vitamin D signaling pathwayQ38356179
Vitamin D: two dihydroxylated metabolites are required for normal chicken egg hatchabilityQ38483768
Molecular biology of the vitamin D hormoneQ39311745
Structure-function relationships in the vitamin D endocrine systemQ40545127
Vitamin D-regulated gene expression.Q40855785
Vitamin D, calcium, and epidermal differentiationQ40906153
Transcription properties of a cell type-specific TATA-binding protein, TRF.Q41086793
TAFs and TFIIA mediate differential utilization of the tandem Adh promotersQ41308314
Modulation of cell growth, differentiation, and production of interleukin-3 by 1 alpha,25-dihydroxyvitamin D3 in the murine myelomonocytic leukemia cell line WEHI-3.Q41344708
TAFs: guilt by association?Q41444675
The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.Q41731155
Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcriptionQ42439013
Regulatory activities of 2 beta-(3-hydroxypropoxy)-1 alpha, 25-dihydroxyvitamin D3, a novel synthetic vitamin D3 derivative, on calcium metabolismQ44333378
ERC-55, a binding protein for the papilloma virus E6 oncoprotein, specifically interacts with vitamin D receptor among nuclear receptorsQ45762820
Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptorsQ46828991
Evidence for ligand-dependent intramolecular folding of the AF-2 domain in vitamin D receptor-activated transcription and coactivator interaction.Q52526986
A canonical structure for the ligand-binding domain of nuclear receptorsQ61818643
The effect of active vitamin D3 analogs and dexamethasone on the expression of osteocalcin gene in rat tibiae in vivoQ67973794
Synthetic studies of vitamin D3 analogues. VIII. Synthesis of 22-oxavitamin D3 analoguesQ69782785
26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitamin D3: A highly potent, long-lasting analog of 1,25-dihydroxyvitamin D3Q70195321
25-hydroxy-26, 26,26,27,27,27-hexafluorovitamin D3: biological activity in the ratQ70535718
Transcriptional activity of a fluorinated vitamin D analog on VDR-RXR-mediated gene expressionQ72403594
Mapping the domains of the interaction of the vitamin D receptor and steroid receptor coactivator-1Q74083189
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectvitaminQ34956
vitamin DQ175621
P304page(s)1049-1055
P577publication date1999-02-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleSelective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog
P478volume19

Reverse relations

cites work (P2860)
Q31943152(23S)- and (23R)-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactone function as antagonists of vitamin D receptor-mediated genomic actions of 1alpha,25-dihydroxyvitamin D(3).
Q284776061α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor
Q37558961A new role for vitamin D receptor activation in chronic kidney disease
Q24545696A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA
Q35117084An update on the therapeutic potential of vitamin D analogues
Q73133819Analysis of the molecular mechanism for the antagonistic action of a novel 1alpha,25-dihydroxyvitamin D(3) analogue toward vitamin D receptor function
Q34566267Antiproliferative action of vitamin D.
Q43248702CDP/cut is an osteoblastic coactivator of the vitamin D receptor (VDR).
Q31943130Central role of VDR conformations for understanding selective actions of vitamin D(3) analogues
Q44081405Combination of 22-oxa-1,25-dihydroxyvitamin D(3), a vitamin D(3) derivative, with vitamin K(2) (VK2) synergistically enhances cell differentiation but suppresses VK2-inducing apoptosis in HL-60 cells
Q34669513Coregulator proteins and corticosteroid action in the brain.
Q60628195Corticosteroid receptors and HPA-axis regulation
Q44539037Design and synthesis of potent vitamin D receptor antagonists with A-ring modifications: remarkable effects of 2alpha-methyl introduction on antagonistic activity
Q47794526Detecting ligands and dissecting nuclear receptor-signaling pathways using recombinant strains of the yeast Saccharomyces cerevisiae
Q28145136Differential mechanisms of nuclear receptor regulation by receptor-associated coactivator 3
Q46977091Direct injection of calcitriol or its analog improves abnormal gene expression in the hyperplastic parathyroid gland in uremia
Q34469351Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer.
Q41375077Drosophila TRAP230/240 are essential coactivators for Atonal in retinal neurogenesis
Q36712981Drug insight: vitamin D analogs in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease
Q28198990Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
Q53425803Excess 25-hydroxyvitamin D3 exacerbates tubulointerstitial injury in mice by modulating macrophage phenotype.
Q42521900Expression and regulation of nuclear receptor coactivators in glucocorticoid action
Q34132690From ligand to response: generating diversity in nuclear receptor coregulator function.
Q33804590Genetic mutation in the human 25-hydroxyvitamin D3 1alpha-hydroxylase gene causes vitamin D-dependent rickets type I.
Q31943055History of the development of new vitamin D analogs: studies on 22-oxacalcitriol (OCT) and 2beta-(3-hydroxypropoxy)calcitriol (ED-71).
Q46633685Human expanded polyglutamine androgen receptor mutants in neurodegeneration as a novel ligand target
Q34435158Identification and characterization of noncalcemic, tissue-selective, nonsecosteroidal vitamin D receptor modulators.
Q43584307Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements
Q40681053Ligand and coactivator identity determines the requirement of the charge clamp for coactivation of the peroxisome proliferator-activated receptor gamma.
Q43653150Ligand recognition by the vitamin D receptor
Q28143758Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators
Q39674733Ligand-selective potentiation of rat mineralocorticoid receptor activation function 1 by a CBP-containing histone acetyltransferase complex
Q39289974Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.
Q36947028Nonclassical aspects of differential vitamin D receptor activation: implications for survival in patients with chronic kidney disease
Q43825196Novel nonsecosteroidal vitamin D receptor modulator inhibits the growth of LNCaP xenograft tumors in athymic mice without increased serum calcium
Q35802815Pharmacology of nuclear receptor-coregulator recognition.
Q24554468Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha
Q55920649RETRACTED: Nuclear Receptor Function Requires a TFTC-Type Histone Acetyl Transferase Complex
Q40605771Remarkable effect of 2[small alpha]-modification on the VDR antagonistic activity of 1small alpha-hydroxyvitamin D3-26,23-lactones
Q42487253Repressive domain of unliganded human estrogen receptor alpha associates with Hsc70.
Q40503211Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative
Q44188850Synthesis and testing of 2alpha-modified 1alpha,25-dihydroxyvitamin D(3) analogues with a double side chain: marked cell differentiation activity
Q39562796Synthesis of C-2 substituted vitamin D derivatives having ringed side chains and their biological evaluation, especially biological effect on bone by modification at the C-2 position
Q22253199The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand
Q37281181The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes
Q37481349Therapeutic applications for novel non-hypercalcemic vitamin D receptor ligands
Q40413870Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching
Q40692111Two novel metabolic pathways of 22-oxacalcitriol (OCT). C-25 dehydration and C-3 epimerization and biological activities of novel OCT metabolites
Q36099016Vitamin D analogs: new therapeutic agents for secondary hyperparathyroidism
Q43991826Vitamin D analogue-specific recruitment of vitamin D receptor coactivators
Q45373448Vitamin D deficiency is associated with increased left ventricular mass and diastolic dysfunction in children with chronic kidney disease
Q35094837Vitamin D metabolism, mechanism of action, and clinical applications
Q36947025Vitamin D receptor activator selectivity in the treatment of secondary hyperparathyroidism: understanding the differences among therapies
Q46704636Vitamin D regulation of cathelicidin in the skin: toward a renaissance of vitamin D in dermatology?
Q31943140Vitamin D(3) analogs (MC 1288, KH 1060, EB 1089, GS 1558, and CB 1093): studies on their mechanism of action.
Q52568905Yeast two-hybrid detection systems that are highly sensitive to a certain kind of endocrine disruptors.
Q57849061p300 Mediates Functional Synergism between AF-1 and AF-2 of Estrogen Receptor α and β by Interacting Directly with the N-terminal A/B Domains

Search more.