Patients on HAART often have an excess of unintegrated HIV DNA: Implications for monitoring reservoirs

scientific article published on January 5, 2011

Patients on HAART often have an excess of unintegrated HIV DNA: Implications for monitoring reservoirs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIROL.2010.08.024
P953full work available at URLhttps://doi.org/10.1016/j.virol.2010.08.024
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20970154/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20970154/pdf/?tool=EBI
https://europepmc.org/articles/PMC3253773
https://europepmc.org/articles/PMC3253773?pdf=render
https://api.elsevier.com/content/article/PII:S0042682210005544?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0042682210005544?httpAccept=text/plain
P932PMC publication ID3253773
P698PubMed publication ID20970154
P5875ResearchGate publication ID47532953

P50authorMatthew J PaceQ82080707
P2093author name stringAngela Mexas
Avinash Bhandoola
Una O'Doherty
Erin Graf
Jianqing J. Yu
Megan K. Liszewski
Luis M. Agosto
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Loss of neoplastic properties in vitro. II. Observations on KB sublinesQ72580566
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Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuliQ34124009
Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loadsQ34312257
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Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infectionQ36225040
Experimental approaches to the study of HIV-1 latencyQ36708954
Integration is not necessary for expression of human immunodeficiency virus type 1 protein productsQ36806287
Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loadsQ36943833
A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patientsQ37030314
Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapyQ37072991
Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection.Q37207653
Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitorsQ37257484
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Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategiesQ37644561
HIV-1 drug resistance profiles in children and adults with viral load of <50 copies/ml receiving combination therapyQ38460522
The CXCR4-tropic human immunodeficiency virus envelope promotes more-efficient gene delivery to resting CD4+ T cells than the vesicular stomatitis virus glycoprotein G envelopeQ38862435
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Human immunodeficiency virus cDNA metabolism: notable stability of two-long terminal repeat circlesQ39683262
A sensitive, quantitative assay for human immunodeficiency virus type 1 integrationQ39685335
Identification and characterization of a temperature-sensitive mutant of human immunodeficiency virus type 1 by alanine scanning mutagenesis of the integrase geneQ39868558
Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirusQ39996408
Integration is essential for efficient gene expression of human immunodeficiency virus type 1.Q40044176
HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration.Q40106981
Repetitive sequences in eukaryotic DNA and their expressionQ40338293
Cell cycle arrest in G2/M promotes early steps of infection by human immunodeficiency virusQ40435980
A quantitative assay for HIV DNA integration in vivoQ40809319
Analysis of human immunodeficiency virus type 1 integrase mutantsQ41321604
Alu sequencesQ41658951
Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replicationQ42616666
HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.Q43130032
Quantification of integrated and total HIV-1 DNA after long-term highly active antiretroviral therapy in HIV-1-infected patientsQ44022665
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecthighly active antiretroviral therapyQ3536652
virus latencyQ4115619
virus integrationQ70684004
P304page(s)46-53
P577publication date2011-01-01
2011-01-05
P1433published inVirologyQ7934867
P1476titlePatients on HAART often have an excess of unintegrated HIV DNA: implications for monitoring reservoirs
Patients on HAART often have an excess of unintegrated HIV DNA: Implications for monitoring reservoirs
P478volume409

Reverse relations

cites work (P2860)
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Q35143730The role of unintegrated DNA in HIV infection