Integration is essential for efficient gene expression of human immunodeficiency virus type 1.

scientific article published on March 1993

Integration is essential for efficient gene expression of human immunodeficiency virus type 1. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID237481
P698PubMed publication ID8437208

P2093author name stringShibata R
Adachi A
Kawamura M
Sakai H
Ueda S
Ono N
Sakuragi S
Ishimoto A
Sakuragi J
P2860cites workRecombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDSQ28262859
SV40-transformed simian cells support the replication of early SV40 mutantsQ28263905
Selective extraction of polyoma DNA from infected mouse cell culturesQ29547500
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular cloneQ29547734
Integration of human immunodeficiency virus type 1 DNA in vitroQ33608319
Construction and use of a replication-competent human immunodeficiency virus (HIV-1) that expresses the chloramphenicol acetyltransferase enzymeQ33859324
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cellsQ34048204
Genetic recombination of human immunodeficiency virusQ36782092
The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and releaseQ36800610
Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutantsQ36806278
Integration is not necessary for expression of human immunodeficiency virus type 1 protein productsQ36806287
In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivityQ36825840
Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirusQ37546388
A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integrationQ37573656
The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locusQ37580568
Development of antiviral drugs for the treatment of AIDS: strategies and prospectsQ38668999
Functional comparison of transactivation by human retrovirus rev and rex genesQ40105610
Mutational analysis of the human immunodeficiency virus vpr open reading frame.Q40116997
Compatibility of rev gene activity in the four groups of primate lentivirusesQ41663845
DNA transfection of mouse lymphoid cells by the combination of DEAE-dextran-mediated DNA uptake and osmotic shock procedureQ41747241
Requirement of the avian retrovirus pp32 DNA binding protein domain for replicationQ43946489
The terminal nucleotides of retrovirus DNA are required for integration but not virus productionQ45797460
Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infectionQ45804335
The HIV 'A' (sor) gene product is essential for virus infectivityQ45847960
The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitroQ45851069
Generation and characterization of the human immunodeficiency virus type 1 mutantsQ45859881
DNA amplification for direct detection of HIV-1 in DNA of peripheral blood mononuclear cellsQ64130379
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1169-1174
P577publication date1993-03-01
P1433published inJournal of VirologyQ1251128
P1476titleIntegration is essential for efficient gene expression of human immunodeficiency virus type 1.
P478volume67

Reverse relations

cites work (P2860)
Q398781603'-end processing and kinetics of 5'-end joining during retroviral integration in vivo.
Q783250923D-QSAR and molecular modeling of HIV-1 integrase inhibitors
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Q33604959AIDS and the lung: update 1995. 4. Role of the human immunodeficiency virus within the lung
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Q39996408Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus
Q40307039Analysis of human immunodeficiency virus type 1 integration by using a specific, sensitive and quantitative assay based on real-time polymerase chain reaction
Q41504287Analysis of long-term viral expression in CEM cells persistently infected with non syncytium-inducing HIV-1 strains
Q36408455Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials
Q41841102Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus
Q37457791Designed zinc finger protein interacting with the HIV-1 integrase recognition sequence at 2-LTR-circle junctions
Q37386023Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR.
Q36538764Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations
Q33782371Efficient gap repair catalyzed in vitro by an intrinsic DNA polymerase activity of human immunodeficiency virus type 1 integrase.
Q33839450Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART.
Q40162909Evidence for gene expression by unintegrated human immunodeficiency virus type 1 DNA species
Q35861729Expression of human immunodeficiency virus type 1 reverse transcriptase in trans during virion release and after infection
Q46612375Gag-Pol region determines the tropism of SIVagm for human cells
Q34950830Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected]
Q38290032Genetic analysis of human immunodeficiency virus type 1 integrase and the U3 att site: unusual phenotype of mutants in the zinc finger-like domain
Q36629409Genetic analysis of the human immunodeficiency virus type 1 integrase protein.
Q54633182HIV-1 integrase blocks infection of bacteria by single-stranded DNA and RNA bacteriophages.
Q28367702HIV-1 integrase catalytic core: molecular dynamics and simulated fluorescence decays
Q45767103High susceptibility of U937-derived subclones to human immunodeficiency virus type 1 infection correlates with accumulation of unintegrated circular viral DNA.
Q39170765Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear Entry
Q34782531Human immunodeficiency virus type 1 (HIV-1) Vpr enhances expression from unintegrated HIV-1 DNA.
Q40048140Human immunodeficiency virus type 1 2-LTR circles reside in a nucleoprotein complex which is different from the preintegration complex.
Q40045880Human immunodeficiency virus type 1 DNA synthesis, integration, and efficient viral replication in growth-arrested T cells.
Q30422793Human immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA.
Q28368861Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism
Q35829884Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
Q35890609Human immunodeficiency virus type 1 nucleocapsid protein specifically stimulates Mg2+-dependent DNA integration in vitro
Q39606712Human immunodeficiency virus type 1 replication in the absence of integrase-mediated dna recombination: definition of permissive and nonpermissive T-cell lines
Q37026630Impact of primary elvitegravir resistance-associated mutations in HIV-1 integrase on drug susceptibility and viral replication fitness
Q34859768Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction
Q39870518Increasing transduction efficiency of recombinant murine retrovirus vectors by initiation of endogenous reverse transcription: potential utility for genetic therapies
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Q33929260Inhibition of the integrase of human immunodeficiency virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31
Q28378926Inhibitors of HIV-1 replication [corrected; erratum to be published] that inhibit HIV integrase
Q36638299Integrase mutants of human immunodeficiency virus type 1 with a specific defect in integration.
Q35839212Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1.
Q33645102Irreversible inhibition of human immunodeficiency virus type 1 integrase by dicaffeoylquinic acids
Q33849497Kinetics of human immunodeficiency virus type 1 (HIV) DNA integration in acutely infected cells as determined using a novel assay for detection of integrated HIV DNA.
Q40939620Localization of HTLV-1 and HIV-1 proviral sequences in chromosomes of persistently infected cells.
Q78043568Molecular electrostatic potentials as input for the alignment of HIV-1 integrase inhibitors in 3D QSAR
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Q34412186Quantitative PCR used to assess HIV-1 integration and 2-LTR circle formation in human macrophages, peripheral blood lymphocytes and a CD4+ cell line
Q37153500Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle
Q36949688Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors
Q28368842Resistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integrase
Q34668065Retroviral Integrase Structure and DNA Recombination Mechanism
Q37204656Retrovirus in salivary glands from patients with Sjögren's syndrome
Q28345957Specific inhibition of human immunodeficiency virus type 1 (HIV-1) integration in cell culture: putative inhibitors of HIV-1 integrase
Q35882489Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase.
Q40883677Styrylquinolines, integrase inhibitors acting prior to integration: a new mechanism of action for anti-integrase agents
Q37399117Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors
Q36078433The Molecular Characterization of Intestinal Explant HIV Infection Using Polymerase Chain Reaction-Based Techniques.
Q33717181The ataxia telangiectasia-mutated and Rad3-related protein is dispensable for retroviral integration
Q37615893Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs
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