scholarly article | Q13442814 |
P2093 | author name string | Michihiko Kuwano | |
Yuji Basaki | |||
Hidetaka Uramoto | |||
Hiroto Izumi | |||
Kimitoshi Kohno | |||
Masayoshi Kage | |||
Kazutaka Nakashima | |||
Akihiko Kawahara | |||
Mayumi Ono | |||
Kosei Yasumoto | |||
Chizuko Yamamoto | |||
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APE1/Ref-1 regulates PTEN expression mediated by Egr-1 | Q24650473 | ||
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain | Q24794765 | ||
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EGFR mutation and resistance of non-small-cell lung cancer to gefitinib | Q27824829 | ||
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling | Q27851406 | ||
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma | Q27860881 | ||
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib | Q27861059 | ||
KRAS mutations in non-small cell lung cancer | Q28240568 | ||
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR | Q28240702 | ||
One hundred years of lung cancer | Q28257141 | ||
The biology and clinical relevance of the PTEN tumor suppressor pathway | Q28272157 | ||
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways | Q28274882 | ||
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers | Q29615475 | ||
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization | Q29618351 | ||
Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival | Q34133497 | ||
Global cancer statistics in the year 2000. | Q34571897 | ||
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PTEN expression elicited by EGR-1 transcription factor in calyculin A-induced apoptotic cells. | Q38334830 | ||
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KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer | Q38432430 | ||
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Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. | Q39916367 | ||
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HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells | Q40421135 | ||
ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells | Q40657593 | ||
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation | Q40732720 | ||
Basic fibroblast growth factor transcriptional autoregulation requires EGR-1. | Q41110093 | ||
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The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling | Q43848062 | ||
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EGFR and HER2 Gene Copy Number and Response to First-Line Chemotherapy in Patients with Advanced Non-small Cell Lung Cancer (NSCLC) | Q64135644 | ||
Transforming growth factor-alpha enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter | Q73960005 | ||
P433 | issue | 21 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | lung cancer | Q47912 |
antineoplastic resistance | Q13416904 | ||
P304 | page(s) | 8715-8725 | |
P577 | publication date | 2010-10-19 | |
P1433 | published in | Cancer Research | Q326097 |
P1476 | title | Loss of PTEN expression by blocking nuclear translocation of EGR1 in gefitinib-resistant lung cancer cells harboring epidermal growth factor receptor-activating mutations | |
Loss of PTEN Expression by Blocking Nuclear Translocation of EGR1 in Gefitinib-Resistant Lung Cancer Cells Harboring Epidermal Growth Factor Receptor–Activating Mutations | |||
P478 | volume | 70 |
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Q51072877 | Alteration of the E-cadherin/β-catenin complex predicts poor response to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment. |
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Q37211974 | Atorvastatin overcomes gefitinib resistance in KRAS mutant human non-small cell lung carcinoma cells |
Q37708873 | BIM deletion polymorphisms in Hispanic patients with non-small cell lung cancer carriers of EGFR mutations |
Q64297990 | Chemotherapy combined with Endostar as salvage treatment for EGFR-tyrosine kinase inhibitor primary resistance in an advanced non-small cell lung cancer patient with EGFR L858R mutation and ROS1 fusion: A case report |
Q38504491 | Clinical approaches to treat patients with non-small cell lung cancer and epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance. |
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Q38543780 | Current and future molecular diagnostics in non-small-cell lung cancer. |
Q36834883 | Drug Resistance to EGFR Inhibitors in Lung Cancer |
Q41122951 | EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop |
Q37180302 | EGFR inhibition in non-small cell lung cancer: current evidence and future directions |
Q37204247 | EGFR protein expression using a specific intracellular domain antibody and PTEN and clinical outcomes in squamous cell lung cancer patients with EGFR-tyrosine kinase inhibitor therapy |
Q49887890 | EGFR-TKIs resistance via EGFR-independent signaling pathways |
Q91937535 | EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis |
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Q37099888 | Elevated neutrophil gelatinase-associated lipocalin contributes to erlotinib resistance in non-small cell lung cancer |
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Q35117568 | From the bench to bedside: biological and methodology considerations for the future of companion diagnostics in nonsmall cell lung cancer |
Q41708722 | High PHLPP1 expression levels predicts longer time of acquired resistance to EGFR tyrosine kinase inhibitors in patients with lung adenocarcinoma |
Q39328532 | JAK2-related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor-activating mutation |
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Q35632411 | Sarcomatous transformation of EGFR and TP53 mutation-positive metastatic adenocarcinoma of the lungs, masquerading as a primary pleomorphic sarcoma of the proximal femur |
Q34201724 | Sequence-dependent effect of docetaxel with gefitinib on the proliferation and apoptosis of lung adenocarcinoma cell H1975 |
Q28391425 | Sequential activation of Elk-1/Egr-1/GADD45α by arsenic |
Q42434753 | Small activating ribonucleic acid reverses tyrosine kinase inhibitor resistance in epidermal growth factor receptor-mutant lung cancer by increasing the expression of phosphatase and tensin homolog |
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Q36247850 | Subsequent treatment of epidermal growth factor receptor-tyrosine kinase inhibitor failure in patients with advanced lung adenocarcinoma |
Q27853317 | TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun |
Q54977358 | Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells. |
Q34852951 | Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells |
Q42378470 | The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells |
Q48695556 | The long non-coding RNA, LINC00635-001, sensitizes EGFR-TKI-resistant human lung cancer cells in vitro by inhibiting Akt activation |
Q50237958 | The novel phosphoinositide 3-kinase-mammalian target of rapamycin inhibitor, BEZ235, circumvents erlotinib resistance of epidermal growth factor receptor mutant lung cancer cells triggered by hepatocyte growth factor. |
Q38390044 | Tumor heterogeneity: evolution through space and time in EGFR mutant non small cell lung cancer patients |
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