Attenuated Salmonella enterica serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimen

scientific article published on September 2002

Attenuated Salmonella enterica serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimen is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.70.9.5096-5106.2002
P932PMC publication ID128259
P698PubMed publication ID12183559

P50authorThomas P. MonathQ59762392
P2093author name stringDonna Freeman
Arthur K Turner
Susan Lewis
Harry Kleanthous
Patricia Londoño-Arcila
Michael J Darsley
Aisling M O'Dowd
Judith Greenwood
Emma L Rees
Timothy J Tibbitts
P2860cites workParenteral adjuvant activities of Escherichia coli heat-labile toxin and its B subunit for immunization of mice against gastric Helicobacter pylori infectionQ24548763
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Urea protects Helicobacter (Campylobacter) pylori from the bactericidal effect of acid.Q30456762
HtrA homologue of Legionella pneumophila: an indispensable element for intracellular infection of mammalian but not protozoan cellsQ30659177
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Rectal and intranasal immunizations with recombinant urease induce distinct local and serum immune responses in mice and protect against Helicobacter pylori infectionQ33755359
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Immunization with recombinant Helicobacter pylori urease in specific-pathogen-free rhesus monkeys (Macaca mulatta).Q34004186
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Selection for urease activity during Helicobacter pylori infection of rhesus macaques (Macaca mulatta).Q34007487
Construction and characterization of genetically defined aro omp mutants of enterotoxigenic Escherichia coli and preliminary studies of safety and immunogenicity in humansQ34008614
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Urease-specific monoclonal antibodies prevent Helicobacter felis infection in miceQ35401490
Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responsesQ36401349
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Serum immunoglobulin G immune response to Helicobacter pylori antigens in Mongolian gerbilsQ39464027
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Safety of live oral Salmonella typhi vaccine strains with deletions in htrA and aroC aroD and immune response in humans.Q39827320
Comparison of the safety and immunogenicity of delta aroC delta aroD and delta cya delta crp Salmonella typhi strains in adult volunteersQ40149266
Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic pigletsQ40151140
A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach.Q40375054
Effect of gastric pH on urease-dependent colonization of gnotobiotic piglets by Helicobacter pyloriQ40375096
Safety and immune responses to attenuated Salmonella enterica serovar typhi oral live vector vaccines expressing tetanus toxin fragment C.Q40613747
Safety and immunogenicity of phoP/phoQ-deleted Salmonella typhi expressing Helicobacter pylori urease in adult volunteersQ40631622
Construction of genetically defined double aro mutants of Salmonella typhiQ40743402
In vitro characterization of Salmonella typhi mutant strains for live oral vaccinesQ40761489
Isolation of stable aroA mutants of Salmonella typhi Ty2: properties and preliminary characterisation in miceQ40797598
The development of oral vaccines based on live attenuated Salmonella strainsQ40842482
Systemic and local immune responses against Helicobacter pylori urease in patients with chronic gastritis: distinct IgA and IgG productive sitesQ42138194
Immunization of rhesus monkeys with a mucosal prime, parenteral boost strategy protects against infection with Helicobacter pyloriQ43618300
Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felisQ43702777
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant.Q43981500
Investigation of effects of anesthesia and age on aspiration in mice through LacZ gene transfer by recombinant E1-deleted adenovirus vectorsQ44016294
Systemic immunization with urease protects mice against Helicobacter pylori infectionQ47971087
Salmonella typhi vaccine strain CVD 908 expressing the circumsporozoite protein of Plasmodium falciparum: strain construction and safety and immunogenicity in humans.Q48014958
Safety and immunogenicity of live recombinant Salmonella enterica serovar Typhi Ty21a expressing urease A and B from Helicobacter pylori in human volunteers.Q50112049
A comparison of immunogenicity and in vivo distribution of Salmonella enterica serovar Typhi and Typhimurium live vector vaccines delivered by mucosal routes in the murine modelQ50120545
Protection of mice against gastric colonization by Helicobacter pylori by single oral dose immunization with attenuated Salmonella typhimurium producing urease subunits A and B.Q50132011
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigensQ50134864
Expression of LacZ from the htrA, nirB and groE promoters in a Salmonella vaccine strain: influence of growth in mammalian cellsQ50144951
Cytokine production patterns and lymphoproliferative responses in volunteers orally immunized with attenuated vaccine strains of Salmonella typhiQ50146372
Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccineQ50174904
Clinical acceptability and immunogenicity of CVD 908 Salmonella typhi vaccine strainQ50181478
Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori ureaseQ72718088
Local and systemic antibody responses in humans with Helicobacter pylori infectionQ73079725
Analysis of host responses of guinea pigs during Helicobacter pylori infectionQ73670177
Rapid recurrence of Helicobacter pylori infection in Peruvian patients after successful eradication. Gastrointestinal Physiology Working Group of the Universidad Peruana Cayetano Heredia and The Johns Hopkins UniversityQ73948566
Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adultsQ74637084
Oral immunization with recombinant Helicobacter pylori urease confers long-lasting immunity against Helicobacter felis infectionQ77297235
Serologic IgG response to urease in Helicobacter pylori-infected persons from MexicoQ77811470
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectHelicobacter pyloriQ180556
Helicobacter pylori infectious diseaseQ4497153
attenuated vaccineQ1810913
Salmonella entericaQ2264864
P304page(s)5096-5106
P577publication date2002-09-01
P1433published inInfection and ImmunityQ6029193
P1476titleAttenuated Salmonella enterica serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimen
P478volume70

Reverse relations

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