Comparison of a regulated delayed antigen synthesis system with in vivo-inducible promoters for antigen delivery by live attenuated Salmonella vaccines

scientific article

Comparison of a regulated delayed antigen synthesis system with in vivo-inducible promoters for antigen delivery by live attenuated Salmonella vaccines is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/IAI.00445-10
P932PMC publication ID3028866
P698PubMed publication ID21134969

P50authorRoy CurtissQ7372720
P2093author name stringWei Sun
Yuhua Li
Kenneth L Roland
Shifeng Wang
Huoying Shi
P2860cites workpH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimuriumQ50125208
Th1 dominance in the immune response to live Salmonella typhimurium requires bacterial invasiveness but not persistenceQ50126498
Environmental regulation of Salmonella pathogenicity island 2 gene expressionQ50126816
Immunogenicity of viral B-cell epitopes inserted into two surface loops of the Escherichia coli K12 LamB protein and expressed in an attenuated aroA strain of Salmonella typhimuriumQ50127205
Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium.Q50131250
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigensQ50134864
Salmonella typhimurium induces IFN-gamma production in murine splenocytes. Role of natural killer cells and macrophages.Q50163402
Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccineQ50174904
A chromosomal integration system for stabilization of heterologous genes in Salmonella based vaccine strainsQ50197025
Stable episomal expression system under control of a stress inducible promoter enhances the immunogenicity of Bacillus subtilis as a vector for antigen delivery.Q54469903
PspA, a protection-eliciting pneumococcal protein: immunogenicity of isolated native PspA in miceQ71619831
IEM101, a naturally attenuated Vibrio cholerae strain as carrier for genetically detoxified derivatives of cholera toxinQ74106308
A Salmonella typhimurium virulence protein is similar to a Yersinia enterocolitica invasion protein and a bacteriophage lambda outer membrane proteinQ24681193
H-NS mediates the silencing of laterally acquired genes in bacteriaQ28490022
Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coliQ29615261
Induction of antibody responses in the common mucosal immune system by respiratory syncytical virus immunostimulating complexesQ30712206
Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometryQ30828698
Interleukin-17A mediates acquired immunity to pneumococcal colonizationQ33370537
lac repressor is an antivirulence factor of Salmonella enterica: its role in the evolution of virulence in SalmonellaQ33460439
Optimization of Salmonella enterica serovar typhi DeltaaroC DeltassaV derivatives as vehicles for delivering heterologous antigens by chromosomal integration and in vivo inducible promotersQ33556968
A new generation of stable, nonantibiotic, low-copy-number plasmids improves immune responses to foreign antigens in Salmonella enterica serovar Typhi live vectorsQ33557714
A recombinant live attenuated strain of Vibrio cholerae induces immunity against tetanus toxin and Bordetella pertussis tracheal colonization factor.Q33752525
Oral vaccination against tetanus: comparison of the immunogenicities of Salmonella strains expressing fragment C from the nirB and htrA promoters.Q33755979
Fine-tuning synthesis of Yersinia pestis LcrV from runaway-like replication balanced-lethal plasmid in a Salmonella enterica serovar typhimurium vaccine induces protection against a lethal Y. pestis challenge in miceQ33877252
SlyA regulates function of Salmonella pathogenicity island 2 (SPI-2) and expression of SPI-2-associated genesQ33883333
Immune responses to recombinant pneumococcal PsaA antigen delivered by a live attenuated Salmonella vaccineQ33963100
Use of in vivo-regulated promoters to deliver antigens from attenuated Salmonella enterica var. TyphimuriumQ34002047
Expression of recombinant enterotoxigenic Escherichia coli colonization factor antigen I by Salmonella typhimurium elicits a biphasic T helper cell response.Q34002657
In vitro and in vivo analyses of constitutive and in vivo-induced promoters in attenuated vaccine and vector strains of Vibrio choleraeQ34003489
Construction and characterization of a Salmonella enterica serovar typhimurium clone expressing a salivary adhesin of Streptococcus mutans under control of the anaerobically inducible nirB promoterQ34003662
Pilot study of phoP/phoQ-deleted Salmonella enterica serovar typhimurium expressing Helicobacter pylori urease in adult volunteersQ34003941
Regulated antigen expression in live recombinant Salmonella enterica serovar Typhimurium strongly affects colonization capabilities and specific CD4(+)-T-cell responsesQ34009711
Aromatic-dependent salmonella as anti-bacterial vaccines and as presenters of heterologous antigens or of DNA encoding themQ34041923
Salmonella vaccine vectors displaying delayed antigen synthesis in vivo to enhance immunogenicityQ34119481
Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica serovar typhimurium vaccineQ34120949
Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoidQ34161056
Intracellular bacteria as targets and carriers for vaccinationQ34280918
Efficacy of intracellular activated promoters for generation of Salmonella-based vaccinesQ34290850
Transfer of eukaryotic expression plasmids to mammalian host cells by bacterial carriersQ34403839
Transcriptome of Salmonella enterica serovar Typhi within macrophages revealed through the selective capture of transcribed sequencesQ34478638
Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicityQ34515348
Further characterization of the PhoP regulon: identification of new PhoP-activated virulence lociQ34545309
Genetic characterization and immunogenicity of coli surface antigen 4 from enterotoxigenic Escherichia coli when it is expressed in a Shigella live-vector strainQ34716080
Delineation of upstream signaling events in the salmonella pathogenicity island 2 transcriptional activation pathway.Q35272629
Runaway-replication plasmids as tools to produce large quantities of proteins from cloned genes in bacteriaQ35302873
Acidification of phagosomes containing Salmonella typhimurium in murine macrophages.Q35506318
Vaccine efficacy of Salmonella strains expressing glycoprotein 63 with different promoters.Q35533712
A recombinant Bacillus anthracis strain producing the Clostridium perfringens Ib component induces protection against iota toxinsQ35548328
Hybrid hepatitis B virus core-pre-S proteins synthesized in avirulent Salmonella typhimurium and Salmonella typhi for oral vaccination.Q35779035
Bacterial infection as assessed by in vivo gene expressionQ35966527
Live-attenuated Salmonella as a prototype vaccine vector for passenger immunogens in humans: are we there yet?Q36837160
Escherichia coli O157:H7 survives within human macrophages: global gene expression profile and involvement of the Shiga toxinsQ36949983
An unusual pagC::TnphoA mutation leads to an invasion- and virulence-defective phenotype in SalmonellaeQ36950718
Evaluation of new generation Salmonella enterica serovar Typhimurium vaccines with regulated delayed attenuation to induce immune responses against PspA.Q37062098
Salmonella enterica serovar Typhi live vector vaccines finally come of ageQ37106127
A global role for Fis in the transcriptional control of metabolism and type III secretion in Salmonella enterica serovar Typhimurium.Q38338833
A recombinant attenuated Salmonella enterica serovar Typhimurium vaccine encoding Eimeria acervulina antigen offers protection against E. acervulina challengeQ38443037
The response regulator SsrB activates expression of diverse Salmonella pathogenicity island 2 promoters and counters silencing by the nucleoid-associated protein H-NS.Q39332980
OmpR regulates the two-component system SsrA-ssrB in Salmonella pathogenicity island 2.Q39498843
Optimization of plasmid maintenance in the attenuated live vector vaccine strain Salmonella typhi CVD 908-htrA.Q39513282
Attenuated Shigella flexneri 2a Delta guaBA strain CVD 1204 expressing enterotoxigenic Escherichia coli (ETEC) CS2 and CS3 fimbriae as a live mucosal vaccine against Shigella and ETEC infectionQ39519924
Attenuated Salmonella enterica serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimenQ39656225
Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of L-arabinose as inducer of bacterial gene expression in vivoQ40171422
Fis is required for proper regulation of ssaG expression in Salmonella enterica serovar TyphimuriumQ40267411
Evaluation of an intracellular-activated promoter for the generation of live Salmonella recombinant vaccinesQ40444726
Rational design of Salmonella-based vaccination strategiesQ40488602
Safety and immune responses to attenuated Salmonella enterica serovar typhi oral live vector vaccines expressing tetanus toxin fragment C.Q40613747
phoP/phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers.Q40668237
Evaluation of a phoP/phoQ-deleted, aroA-deleted live oral Salmonella typhi vaccine strain in human volunteers.Q40674810
Enhanced immune responses to viral epitopes by combining macrophage-inducible expression with multimeric display on a Salmonella vectorQ40815708
Fluorescence-based isolation of bacterial genes expressed within host cellsQ41090281
Oral vaccination with salmonella simultaneously expressing Yersinia pestis F1 and V antigens protects against bubonic and pneumonic plagueQ41450645
Antibody responses to Yersinia pestis F1-antigen expressed in Salmonella typhimurium aroA from in vivo-inducible promotersQ41479815
Evidence for a common mucosal immunologic system. I. Migration of B immunoblasts into intestinal, respiratory, and genital tissuesQ41632896
Ability of SPI2 mutant of S. typhi to effectively induce antibody responses to the mucosal antigen enterotoxigenic E. coli heat labile toxin B subunit after oral delivery to humansQ41886615
Formation of a novel surface structure encoded by Salmonella Pathogenicity Island 2.Q42023974
Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella entericaQ43533379
The PhoP/PhoQ system controls the intramacrophage type three secretion system of Salmonella entericaQ44016971
Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein production: 1. Readjustment of metabolic enzyme synthesisQ44134222
Vaccination against type F botulinum toxin using attenuated Salmonella enterica var Typhimurium strains expressing the BoNT/F H(C) fragmentQ44297896
Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigenQ44761763
The roles of SsrA-SsrB and OmpR-EnvZ in the regulation of genes encoding the Salmonella typhimurium SPI-2 type III secretion systemQ45020170
Can a 'flawless' live vector vaccine strain be engineered?Q45197812
An Escherichia coli hemolysin transport system-based vector for the export of polypeptides: export of Shiga-like toxin IIeB subunit by Salmonella typhimurium aroA.Q47960715
Expression of in vivo-inducible Salmonella enterica promoters during infection of Caenorhabditis elegansQ50065619
Investigation of ansB and sspA derived promoters for multi- and single-copy antigen expression in attenuated Salmonella enterica var. typhimuriumQ50089440
Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ.Q50091911
The response regulator SsrB activates transcription and binds to a region overlapping OmpR binding sites at Salmonella pathogenicity island 2.Q50095966
Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL.Q50096705
Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG.Q50097559
Dual regulation by phospho-OmpR of ssrA/B gene expression in Salmonella pathogenicity island 2.Q50103896
Novel use of anaerobically induced promoter, dmsA, for controlled expression of fragment C of tetanus toxin in live attenuated Salmonella enterica serovar Typhi strain CVD 908-htrA.Q50117339
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectattenuated vaccineQ1810913
P304page(s)937-949
P577publication date2010-12-06
P1433published inInfection and ImmunityQ6029193
P1476titleComparison of a regulated delayed antigen synthesis system with in vivo-inducible promoters for antigen delivery by live attenuated Salmonella vaccines
P478volume79

Reverse relations

cites work (P2860)
Q91750540A Novel Cre Recombinase-Mediated In Vivo Minicircle DNA (CRIM) Vaccine Provides Partial Protection against Newcastle Disease Virus
Q37123734A colanic acid operon deletion mutation enhances induction of early antibody responses by live attenuated Salmonella vaccine strains
Q35213546A quorum sensing-based in vivo expression system and its application in multivalent bacterial vaccine
Q37425256Assessment of attenuated Salmonella vaccine strains in controlling experimental Salmonella Typhimurium infection in chickens
Q34421752Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines
Q34316015Development of Streptococcus pneumoniae Vaccines Using Live Vectors
Q34627454Development of a Fur-dependent and tightly regulated expression system in Escherichia coli for toxic protein synthesis
Q94587492Differentially regulated promoters for antigen expression in Salmonella vaccine strains
Q47127930Evaluation of Recombinant Attenuated Salmonella Vaccine Strains for Broad Protection against Extraintestinal Pathogenic Escherichia coli
Q36911282Evaluation of regulated delayed attenuation strategies for Salmonella enterica serovar Typhi vaccine vectors in neonatal and infant mice
Q35829353In Vivo Programmed Gene Expression Based on Artificial Quorum Networks
Q34298699LcrV delivered via type III secretion system of live attenuated Yersinia pseudotuberculosis enhances immunogenicity against pneumonic plague
Q28084076Live-Attenuated Bacterial Vectors: Tools for Vaccine and Therapeutic Agent Delivery
Q36970553Low-pH rescue of acid-sensitive Salmonella enterica Serovar Typhi Strains by a Rhamnose-regulated arginine decarboxylase system
Q36653379New technologies in developing recombinant attenuated Salmonella vaccine vectors
Q41868899Novel methods for expression of foreign antigens in live vector vaccines
Q36372952Oral administration of a recombinant attenuated Yersinia pseudotuberculosis strain elicits protective immunity against plague
Q91689946Regulated Delayed Shigella flexneri 2a O-antigen Synthesis in Live Recombinant Salmonella enterica Serovar Typhimurium Induces Comparable Levels of Protective Immune Responses with Constitutive Antigen Synthesis System
Q49644946Salmonella Vaccines: Conduits for Protective Antigens
Q27011946Salmonella as a vaccine delivery vehicle
Q50016846Utilizing Salmonella for antigen delivery: the aims and benefits of bacterial delivered vaccination

Search more.