A new generation of stable, nonantibiotic, low-copy-number plasmids improves immune responses to foreign antigens in Salmonella enterica serovar Typhi live vectors

scientific article

A new generation of stable, nonantibiotic, low-copy-number plasmids improves immune responses to foreign antigens in Salmonella enterica serovar Typhi live vectors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00916-09
P932PMC publication ID2798174
P698PubMed publication ID19884333
P5875ResearchGate publication ID38062431

P50authorMarcela F. PasettiQ56380831
Myron M. LevineQ29564379
P2093author name stringHaim Levy
William C Blackwelder
James E Galen
Jin Yuan Wang
Magaly Chinchilla
Jeffrey E Vogel
Christopher Vindurampulle
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Mucosal immunization with attenuated Salmonella enterica serovar Typhi expressing protective antigen of anthrax toxin (PA83) primes monkeys for accelerated serum antibody responses to parenteral PA83 vaccineQ28387065
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In vivo characterization of the murine intranasal model for assessing the immunogenicity of attenuated Salmonella enterica serovar Typhi strains as live mucosal vaccines and as live vectorsQ34003031
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Safety and immunogenicity in humans of an attenuated Salmonella typhi vaccine vector strain expressing plasmid-encoded hepatitis B antigens stabilized by the Asd-balanced lethal vector systemQ35553394
Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracisQ35783791
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Use of mchI encoding immunity to the antimicrobial peptide microcin H47 as a plasmid selection marker in attenuated bacterial live vectorsQ36898558
Adaptation of the endogenous Salmonella enterica serovar Typhi clyA-encoded hemolysin for antigen export enhances the immunogenicity of anthrax protective antigen domain 4 expressed by the attenuated live-vector vaccine strain CVD 908-htrA.Q37623663
Escherichia coli single-stranded DNA-binding protein: multiple DNA-binding modes and cooperativitiesQ38312769
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208.Q39146446
Optimization of plasmid maintenance in the attenuated live vector vaccine strain Salmonella typhi CVD 908-htrA.Q39513282
Single-stranded DNA binding proteins required for DNA replicationQ39740421
Standardized, mathematical model-based and validated in vitro analysis of anthrax lethal toxin neutralizationQ40008502
Attenuated Salmonella typhi and Shigella as live oral vaccines and as live vectorsQ40655503
Construction of genetically defined double aro mutants of Salmonella typhiQ40743402
Ability of SPI2 mutant of S. typhi to effectively induce antibody responses to the mucosal antigen enterotoxigenic E. coli heat labile toxin B subunit after oral delivery to humansQ41886615
Effect of plasmid copy number and lac operator sequence on antibiotic-free plasmid selection by operator-repressor titration in Escherichia coliQ45071360
Protective immunity against herpes simplex virus (HSV) type 1 following oral administration of recombinant Salmonella typhimurium vaccine strains expressing HSV antigensQ45764942
Natural transfer of sulphonamide and ampicillin resistance between Escherichia coli residing in the human intestineQ46289169
Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion systemQ50079113
Immune responses dependent on antigen location in recombinant attenuated Salmonella typhimurium vaccines following oral immunizationQ50103516
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigensQ50134864
Clinical acceptability and immunogenicity of CVD 908 Salmonella typhi vaccine strainQ50181478
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectSalmonella entericaQ2264864
P304page(s)337-347
P577publication date2009-11-02
P1433published inInfection and ImmunityQ6029193
P1476titleA new generation of stable, nonantibiotic, low-copy-number plasmids improves immune responses to foreign antigens in Salmonella enterica serovar Typhi live vectors
P478volume78

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cites work (P2860)
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