IFNγ expression by an attenuated strain of Salmonella enterica serovar Typhimurium improves vaccine efficacy in susceptible TLR4-defective C3H/HeJ mice

scientific article published on 10 June 2012

IFNγ expression by an attenuated strain of Salmonella enterica serovar Typhimurium improves vaccine efficacy in susceptible TLR4-defective C3H/HeJ mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1043957183
P356DOI10.1007/S00430-012-0248-Z
P698PubMed publication ID22684724
P5875ResearchGate publication ID225287293

P2093author name stringBasel K Al-Ramadi
Maria J Fernandez-Cabezudo
C B Tara Moore
Samia M Al-Ojali
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A new generation of stable, nonantibiotic, low-copy-number plasmids improves immune responses to foreign antigens in Salmonella enterica serovar Typhi live vectorsQ33557714
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Regulated antigen expression in live recombinant Salmonella enterica serovar Typhimurium strongly affects colonization capabilities and specific CD4(+)-T-cell responsesQ34009711
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Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicityQ34515348
Oral priming with Salmonella Typhi vaccine strain CVD 909 followed by parenteral boost with the S. Typhi Vi capsular polysaccharide vaccine induces CD27+IgD-S. Typhi-specific IgA and IgG B memory cells in humansQ34562262
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Systemic infection of mice by wild-type but not Spv- Salmonella typhimurium is enhanced by neutralization of gamma interferon and tumor necrosis factor alphaQ35560441
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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)Q36367812
Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo.Q36380558
Dissociation of innate susceptibility to Salmonella infection and endotoxin responsiveness in C3HeB/FeJ mice and other strains in the C3H lineage.Q36441108
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Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimuriumQ39509475
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccinesQ39513114
Nramp1 transfection transfers Ity/Lsh/Bcg-related pleiotropic effects on macrophage activation: influence on antigen processing and presentation.Q39827277
Modulation of macrophage proinflammatory functions by cytokine-expressing Salmonella vectorsQ39932649
Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of L-arabinose as inducer of bacterial gene expression in vivoQ40171422
Capacity of recombinant gamma interferon to activate macrophages for Salmonella-killing activityQ40426239
Cellular immunity induced by avirulent Salmonella in LPS-defective C3H/HeJ miceQ40825674
Ability of SPI2 mutant of S. typhi to effectively induce antibody responses to the mucosal antigen enterotoxigenic E. coli heat labile toxin B subunit after oral delivery to humansQ41886615
Activation of innate immune responses by IL-2-expressing Salmonella typhimurium is independent of Toll-like receptor 4.Q47352587
Delivery of epitopes by the Salmonella type III secretion system for vaccine developmentQ47793303
Poor survival but high immunogenicity of IL-2-expressing Salmonella typhimurium in inherently resistant miceQ47860145
Toll-like receptors are temporally involved in host defenseQ47914772
Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar typhimurium infection, but not for the initiation of bacterial clearanceQ50052089
Potent anti-tumor activity of systemically-administered IL2-expressing Salmonella correlates with decreased angiogenesis and enhanced tumor apoptosisQ50058791
CD154 is essential for protective immunity in experimental salmonella infection: evidence for a dual role in innate and adaptive immune responsesQ50084899
Induction of innate immunity by IL-2-expressing Salmonella confers protection against lethal infectionQ50104952
Interferon-gamma plays a critical role in intestinal immunity against Salmonella typhimurium infectionQ50122081
Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium.Q50131250
Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular locationQ50139291
Expression of human IL-1 beta in Salmonella typhimurium. A model system for the delivery of recombinant therapeutic proteins in vivoQ50180383
The initial suppression of bacterial growth in a salmonella infection is mediated by a localized rather than a systemic responseQ50201535
Immunity to infection with Salmonella typhimurium: mouse-strain differences in vaccine- and serum-mediated protectionQ50207681
Defect in macrophage effector function confers Salmonella typhimurium susceptibility on C3H/HeJ miceQ50214359
Genetic Control of Leucocyte Responses to EndotoxinQ50245835
P433issue1
P921main subjecttoll-like receptorQ408004
attenuated vaccineQ1810913
Salmonella entericaQ2264864
P304page(s)49-61
P577publication date2012-06-10
P1433published inMedical Microbiology and ImmunologyQ15760239
P1476titleIFNγ expression by an attenuated strain of Salmonella enterica serovar Typhimurium improves vaccine efficacy in susceptible TLR4-defective C3H/HeJ mice
P478volume202

Reverse relations

Q55512573Induction of Hypergammaglobulinemia and Autoantibodies by Salmonella Infection in MyD88-Deficient Mice.cites workP2860

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