High expression of ErbB2 contributes to cholangiocarcinoma cell invasion and proliferation through AKT/p70S6K

scientific article published on August 28, 2010

High expression of ErbB2 contributes to cholangiocarcinoma cell invasion and proliferation through AKT/p70S6K is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3748/WJG.V16.I32.4047
P8608Fatcat IDrelease_czur23ewk5e35gwcbedvtarzju
P953full work available at URLhttps://doi.org/10.3748/wjg.v16.i32.4047
https://europepmc.org/articles/PMC2928458
https://europepmc.org/articles/PMC2928458?pdf=render
P932PMC publication ID2928458
P698PubMed publication ID20731018
P5875ResearchGate publication ID50392862

P2093author name stringTuangporn Suthiphongchai
Warapen Treekitkarnmongkol
P2860cites workc-erbB-2 protein is expressed in hepatolithiasis and cholangiocarcinomaQ77581743
Expression of c-erbB-2 proto-oncogene in extrahepatic cholangiocarcinoma and its clinical significanceQ80775649
Worldwide trends in mortality from biliary tract malignanciesQ21093310
PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migrationQ23924064
Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent associationQ24297029
Detection of hepatocyte growth factor/scatter factor receptor (c-Met) in axillary drainage after operations for breast cancer using reverse transcriptase-polymerase chain reactionQ24803522
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Receptor tyrosine kinase signalling as a target for cancer intervention strategiesQ28188287
A new therapeutic antibody masks ErbB2 to its partnersQ28257173
The concept of synthetic lethality in the context of anticancer therapyQ28268061
Epidemiology, risk factors, and pathogenesis of cholangiocarcinomaQ28293076
The ErbB signaling network: receptor heterodimerization in development and cancerQ29617919
Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissueQ30978459
Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasionQ33529782
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancerQ33890758
The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisQ34493341
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogeneQ34560337
Oncogene expression in cholangiocarcinoma and in normal hepatic developmentQ34668400
Establishment and characterization of an opisthorchiasis-associated cholangiocarcinoma cell line (KKU-100).Q35045355
FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinomaQ35588892
Different mechanisms are implicated in ERBB2 gene overexpression in breast and in other cancersQ36671789
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.Q37015151
Diagnosis and management of cholangiocarcinoma.Q37140020
Her2-positive breast cancer: herceptin and beyond.Q37330891
Role of ErbB family receptor tyrosine kinases in intrahepatic cholangiocarcinomaQ37351498
ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditionsQ38455863
In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 productQ39993985
Selective inhibition of ion transport mechanisms regulating intracellular pH reduces proliferation and induces apoptosis in cholangiocarcinoma cells.Q40230690
Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathwayQ40256045
Activation of p70S6K induces expression of matrix metalloproteinase 9 associated with hepatocyte growth factor-mediated invasion in human ovarian cancer cellsQ40318308
Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinomaQ40390223
Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells.Q40456753
Antisense oligonucleotides specific for the HER2/neu oncogene inhibit the growth of human breast carcinoma cells that overexpress HER2/neuQ41017774
Establishment and characterization of a cholangiocarcinoma cell line from a Thai patient with intrahepatic bile duct cancerQ41655575
Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibodyQ41895244
Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification.Q43607758
The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma.Q46160697
c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma.Q52122642
Gene amplification and protein overexpression of HER-2/neu in human extrahepatic cholangiocarcinoma as detected by chromogenic in situ hybridization and immunohistochemistry: its prognostic implication in node-positive patients.Q53577314
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectcholangiocarcinomaQ124292
intrahepatic bile ductQ12233655
bile duct neoplasmQ56014549
P304page(s)4047-4054
P577publication date2010-08-01
2010-08-28
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleHigh expression of ErbB2 contributes to cholangiocarcinoma cell invasion and proliferation through AKT/p70S6K
P478volume16

Reverse relations

cites work (P2860)
Q36962011Cholangiocarcinoma: Biology, Clinical Management, and Pharmacological Perspectives
Q34598522ErbB2 receptor over-expression improves post-traumatic peripheral nerve regeneration in adult mice
Q35681554High level of urokinase plasminogen activator contributes to cholangiocarcinoma invasion and metastasis
Q36577722MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2
Q90072359Multifaceted Aspects of Metabolic Plasticity in Human Cholangiocarcinoma: An Overview of Current Perspectives
Q51804426Role of ErbB2 mediated AKT and MAPK pathway in gall bladder cell proliferation induced by argemone oil and butter yellow. Argemone oil and butter yellow induced gall bladder cell proliferation.
Q37628969Therapeutic implication of HER2 in advanced biliary tract cancer
Q40151513Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma.