Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody

scientific article published on May 1995

Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/BJC.1995.187
P932PMC publication ID2033805
P698PubMed publication ID7734322
P5875ResearchGate publication ID15465511

P2093author name stringNakamura H
Tokuda Y
Yoshimura M
Shimamura K
Ohnishi Y
Tamaoki N
Ueyama Y
Iwasawa M
P2860cites workMonoclonal antibodies against the extracellular domain of the erbB-2 receptor function as partial ligand agonistsQ67883623
Mouse monoclonal antibodies for experimental immunotherapy promotes killing of tumor cellsQ67970501
Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologueQ68131177
Evaluation of immunoreactivity for erbB-2 protein as a marker of poor short term prognosis in gastric cancerQ68290745
Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodiesQ72228246
Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene productQ28256232
Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodiesQ28282033
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogeneQ28286890
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancerQ29547699
Growth factor receptor tyrosine kinasesQ34164164
Regulation of phosphorylation of the c-erbB-2/HER2 gene product by a monoclonal antibody and serum growth factor(s) in human mammary carcinoma cellsQ36684680
p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factorQ36767887
Mechanistic aspects of the opposing effects of monoclonal antibodies to the ERBB2 receptor on tumor growthQ37600965
Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogeneQ40659427
A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell linesQ41668009
Selection of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/NEU gene amplification.Q41690323
p185neu expression in human lung adenocarcinomas predicts shortened survivalQ41725055
Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodiesQ42819445
Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivoQ44708292
Amplification, overexpression, and rearrangement of the erbB-2 protooncogene in primary human stomach carcinomas.Q45166137
Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissuesQ46076087
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptorQ48369441
Amplification of a novel v-erbB-related gene in a human mammary carcinomaQ48375434
Responsiveness of human gastric tumors implanted in nude mice to clinically equivalent doses of various antitumor agents.Q54943265
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)969-973
P577publication date1995-05-01
P1433published inBritish Journal of CancerQ326309
P1476titleProlonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody
P478volume71

Reverse relations

cites work (P2860)
Q40840650A Humanized Anti-c-erbB-2 Monoclonal Antibody for the Treatment of Breast Cancer
Q40184647Amrubicin, a novel 9-aminoanthracycline, enhances the antitumor activity of chemotherapeutic agents against human cancer cells in vitro and in vivo
Q40227146Anti-tumor immunity induced by an anti-idiotype antibody mimicking human Her-2/neu
Q42834569Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor
Q34244922Clinical development of trastuzumab in breast cancer
Q38729111ErbB Family Signalling: A Paradigm for Oncogene Addiction and Personalized Oncology
Q36438366Establishing a link between oncogenes and tumor angiogenesis
Q40930413H-ras-transformed NRK-52E renal epithelial cells have altered growth, morphology, and cytoskeletal structure that correlates with renal cell carcinoma in vivo
Q41438696HER-2/neu protein: a target for antigen-specific immunotherapy of human cancer.
Q34211018Herceptin: from the bench to the clinic
Q39664471High expression of ErbB2 contributes to cholangiocarcinoma cell invasion and proliferation through AKT/p70S6K
Q39993985In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product
Q40759616Reversion of the malignant phenotype of gastric cancer cell SGC7901 by c-erbB-2-specific hammerhead ribozyme.
Q40857892The growth and metastasis of human, HER-2/neu-overexpressing tumor cell lines in male SCID mice
Q34103663Tyrosine kinases and gastric cancer
Q35110970p185, an immunodominant epitope, is an autoantigen mimotope.

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