Drug susceptibilities of yeast cells are affected by membrane lipid composition

scientific article published on December 2002

Drug susceptibilities of yeast cells are affected by membrane lipid composition is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.46.12.3695-3705.2002
P932PMC publication ID132749
P698PubMed publication ID12435664
P5875ResearchGate publication ID11031542

P50authorRajendra PrasadQ89926093
P2093author name stringAvmeet Kohli
Kasturi Mukhopadhyay
P2860cites workBiochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast saccharomyces cerevisiae.Q27930059
PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugsQ27930853
Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeastQ27932650
ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1pQ27936618
Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungalsQ28293585
Role of multidrug resistance P-glycoproteins in cholesterol esterificationQ28301262
Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter.Q32133639
Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexateQ33630438
Isolation of a putative Candida albicans transcriptional regulator involved in pleiotropic drug resistance by functional complementation of a pdr1 pdr3 mutation in Saccharomyces cerevisiaeQ33634941
Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.Q33721804
Analysis of the tangled relationships between P-glycoprotein-mediated multidrug resistance and the lipid phase of the cell membraneQ33815754
Cloning by gene amplification of two loci conferring multiple drug resistance in SaccharomycesQ33908727
Quantitation of ergosterol content: novel method for determination of fluconazole susceptibility of Candida albicansQ33963057
Multiple resistant phenotypes of Candida albicans coexist during episodes of oropharyngeal candidiasis in human immunodeficiency virus-infected patientsQ33977103
Purification, reconstitution, and inhibition of cytochrome P-450 sterol delta22-desaturase from the pathogenic fungus Candida glabrata.Q33977200
Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transportersQ33983544
Specific chromosome alterations in fluconazole-resistant mutants of Candida albicansQ33992463
Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a reviewQ34059049
Comparison of visual and spectrophotometric methods of broth microdilution MIC end point determination and evaluation of a sterol quantitation method for in vitro susceptibility testing of fluconazole and itraconazole against trailing and nontrailinQ34110565
Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequencesQ34569070
Drug resistance in yeasts--an emerging scenarioQ34695128
Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemiaQ35131728
Molecular biological characterization of an azole-resistant Candida glabrata isolateQ35138586
Plasma membrane translocation of fluorescent-labeled phosphatidylethanolamine is controlled by transcription regulators, PDR1 and PDR3Q36268129
Sequencing, disruption, and characterization of the Candida albicans sterol methyltransferase (ERG6) gene: drug susceptibility studies in erg6 mutantsQ39558473
In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetryQ39651398
Sterols in Candida albicans mutants resistant to polyene or azole antifungals, and of a double mutant C. albicans 6.4.Q39685100
Resistance of Candida albicans to azole antifungal agentsQ40727027
Specificity of drug transport mediated by CaMDR1: a major facilitator of Candida albicansQ40778850
The P-glycoprotein multidrug transporter: interactions with membrane lipids, and their modulation of activityQ41655671
Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domainsQ42800313
Modulation of fluconazole sensitivity by the interaction of mitochondria and erg3p in Saccharomyces cerevisiaeQ43487597
CaALK8, an alkane assimilating cytochrome P450, confers multidrug resistance when expressed in a hypersensitive strain of Candida albicansQ43728432
ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocatorsQ43900293
Sterol-dependent regulation of sphingolipid metabolism in Saccharomyces cerevisiaeQ43990141
ERG6 and PDR5 regulate small lipophilic drug accumulation in yeast cells via distinct mechanismsQ44030158
Modulation of P-glycoprotein-mediated drug transport by alterations in lipid fluidity of rat liver canalicular membrane vesiclesQ44377409
Standardization of antifungal susceptibility testing and clinical relevance.Q45116576
Cloning, sequencing, expression and allelic sequence diversity of ERG3 (C-5 sterol desaturase gene) in Candida albicansQ47940968
The yeast multidrug resistance pump, Pdr5p, confers reduced drug resistance in erg mutants of Saccharomyces cerevisiae.Q52534822
Phospholipid and sterol analysis of plasma membranes of azole-resistant Candida albicans strains.Q54057901
Membrane fluidity affects functions of Cdr1p, a multidrug ABC transporter of Candida albicans.Q54097600
Asymmetric distribution of phosphatidylethanolamine in C. albicans: possible mediation by CDR1, a multidrug transporter belonging to ATP binding cassette (ABC) superfamily.Q54104444
The lipid composition of azole-sensitive and azole-resistant strains of Candida albicans.Q54423176
Coordinate Control of Sphingolipid Biosynthesis and Multidrug Resistance inSaccharomyces cerevisiaeQ57371970
Role of multidrug resistance P-glycoproteins in cholesterol biosynthesisQ70937676
Resistance to fluconazole and amphotericin in Candida albicans from AIDS patientsQ71832854
Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol delta5,6-desaturationQ72989562
Efflux-mediated resistance to fluconazole could be modulated by sterol homeostasis in Saccharomyces cerevisiaeQ74138000
Identification of polymorphic mutant alleles of CaMDR1, a major facilitator of Candida albicans which confers multidrug resistance, and its in vitro transcriptional activationQ77323771
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)3695-3705
P577publication date2002-12-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleDrug susceptibilities of yeast cells are affected by membrane lipid composition
P478volume46

Reverse relations

cites work (P2860)
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