IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

scientific article published on 29 July 2010

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2009-12-260711
P698PubMed publication ID20671123
P5875ResearchGate publication ID45423855

P50authorVéronique BaudQ28320137
Lise WillemsQ43144891
Jerome TamburiniQ48282150
Didier BouscaryQ48282168
Nicolas ChapuisQ51322110
Valérie BardetQ56167780
Norbert IfrahQ56549745
Sophie ParkQ62669751
P2093author name stringGeorges Bismuth
François Dreyfus
Catherine Lacombe
Patrick Mayeux
Alexa S Green
Fabrice Agou
Frederique Verdier
Laurent Leotoing
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P1104number of pages11
P304page(s)4240-4250
P577publication date2010-07-29
P1433published inBloodQ885070
P1476titleIκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia
P478volume116

Reverse relations

cites work (P2860)
Q48721287A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program
Q33792991A splicing variant of NME1 negatively regulates NF-κB signaling and inhibits cancer metastasis by interacting with IKKβ
Q39199734AKT collaborates with ERG and Gata1s to dysregulate megakaryopoiesis and promote AMKL.
Q39328413Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia: involvement of FOXO3a
Q36914091Acute myeloid leukaemia: optimal management and recent developments
Q37888960Applications of post-translational modifications of FoxO family proteins in biological functions
Q26781364Caenorhabditis elegans DAF-16/FOXO transcription factor and its mammalian homologs associate with age-related disease
Q89983202Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation
Q29617418Crosstalk in NF-κB signaling pathways
Q46887116Decitabine-Induced Changes in Human Myelodysplastic Syndrome Cell Line SKM-1 Are Mediated by FOXO3A Activation.
Q41377055FOXO Signaling Pathways as Therapeutic Targets in Cancer
Q38674456FOXO transcription factors in cancer development and therapy
Q26853741FOXO transcription factors throughout T cell biology
Q34221760FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma.
Q46443231FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage
Q90226885FOXO3a from the Nucleus to the Mitochondria: A Round Trip in Cellular Stress Response
Q50137602FoxO transcription factors in cancer metabolism
Q35318592Hypothalamic inflammation: a double-edged sword to nutritional diseases
Q34730816IKBKE phosphorylation and inhibition of FOXO3a: a mechanism of IKBKE oncogenic function
Q35857192Inflammatory cause of metabolic syndrome via brain stress and NF-κB.
Q39062437Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML.
Q30427503Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression
Q34442297Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation
Q37173070NF-κB-driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance.
Q33675855PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells.
Q35474548Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrix
Q35810507Pelle Modulates dFoxO-Mediated Cell Death in Drosophila
Q50057271Regulation of FOXO Factors in Mammalian Cells.
Q37995693Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer
Q37865381Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
Q39590044Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.
Q34173253Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway
Q37440267The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells
Q35001723The IκB kinase complex in NF-κB regulation and beyond
Q37837732Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.
Q101564352Therapeutic strategies targeting FOXO transcription factors
Q92090915Tyrosine nitrations impaired intracellular trafficking of FSHR to the cell surface and FSH-induced Akt-FoxO3a signaling in human granulosa cells
Q35781570miR-93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway