| scholarly article | Q13442814 |
| P50 | author | Stanley J. Korsmeyer | Q138795 |
| P2093 | author name string | Philippe Juin | |
| Gerard Evan | |||
| Lamorna Brown Swigart | |||
| Abigail Hunt | |||
| Beatrice Griffiths | |||
| Trevor Littlewood | |||
| P2860 | cites work | Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria | Q22008484 |
| Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC | Q22009974 | ||
| PUMA induces the rapid apoptosis of colorectal cancer cells | Q24291462 | ||
| PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 | ||
| Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis | Q24324204 | ||
| Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis | Q24533270 | ||
| PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family | Q24608240 | ||
| Movement of Bax from the cytosol to mitochondria during apoptosis | Q24677881 | ||
| Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis | Q27734734 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex | Q28141249 | ||
| Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis | Q28144256 | ||
| Proliferation, cell cycle and apoptosis in cancer | Q28189476 | ||
| BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis | Q28189945 | ||
| Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis | Q28283313 | ||
| Tumor suppressor p53 is a direct transcriptional activator of the human bax gene | Q28306186 | ||
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
| Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations | Q28506809 | ||
| Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis | Q28511080 | ||
| The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues | Q28512628 | ||
| Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis | Q28593886 | ||
| Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane | Q28647586 | ||
| Induction of apoptosis in fibroblasts by c-myc protein | Q29614346 | ||
| Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization | Q29614701 | ||
| Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF | Q29619663 | ||
| Myc potentiates apoptosis by stimulating Bax activity at the mitochondria | Q33968823 | ||
| Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. | Q34011633 | ||
| Apoptotic cell death induced by c-myc is inhibited by bcl-2. | Q34255589 | ||
| Cooperative interaction between c-myc and bcl-2 proto-oncogenes | Q34255596 | ||
| BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak | Q35079498 | ||
| E1A signaling to p53 involves the p19(ARF) tumor suppressor | Q35206764 | ||
| Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria | Q35373938 | ||
| bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis | Q36040551 | ||
| Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization. | Q36328358 | ||
| Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2 | Q36678903 | ||
| A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins | Q38295120 | ||
| The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein | Q38361692 | ||
| Bax is a transcriptional target and mediator of c-myc-induced apoptosis. | Q39424255 | ||
| c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release | Q40443976 | ||
| Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. | Q40731052 | ||
| c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. | Q40792572 | ||
| Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak | Q41134694 | ||
| Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. | Q41414258 | ||
| Mediation of c-Myc-induced apoptosis by p53. | Q41441186 | ||
| p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release. | Q41723055 | ||
| The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant | Q41723645 | ||
| Bcl-2-family proteins: the role of the BH3 domain in apoptosis | Q47686942 | ||
| Apoptosis. Till death us do part | Q48800657 | ||
| Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. | Q53425055 | ||
| Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice | Q57338707 | ||
| Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl-2 | Q57580273 | ||
| TNF-alpha signals apoptosis through a bid-dependent conformational change in Bax that is inhibited by E1B 19K | Q64380526 | ||
| The activity of the murine Bax promoter is regulated by Sp1/3 and E-box binding proteins but not by p53 | Q73050773 | ||
| Regulation of apoptosis by BH3 domains in a cell-free system | Q73908307 | ||
| A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy | Q74117541 | ||
| A matter of life and cell death | Q77164675 | ||
| Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases | Q77388207 | ||
| P433 | issue | 17 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 6158-6169 | |
| P577 | publication date | 2002-09-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | c-Myc functionally cooperates with Bax to induce apoptosis | |
| P478 | volume | 22 |
| Q42835091 | A Bax/Bak-independent mitochondrial death pathway triggered by Drosophila Grim GH3 domain in mammalian cells |
| Q34581441 | Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cells |
| Q35915905 | Apoptosis and colorectal cancer |
| Q43164842 | Apoptotic effects of Physalis minima L. chloroform extract in human breast carcinoma T-47D cells mediated by c-myc-, p53-, and caspase-3-dependent pathways |
| Q37310199 | Apoptotic signaling by c-MYC. |
| Q35092230 | Apoptotic signaling cascades. |
| Q35236066 | BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues |
| Q36695757 | Bax regulates c-Myc-induced mammary tumour apoptosis but not proliferation in MMTV-c-myc transgenic mice |
| Q37373448 | Bcl2 family proteins in carcinogenesis and the treatment of cancer. |
| Q28253441 | Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity |
| Q80622205 | Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells |
| Q40477763 | Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage. |
| Q24316499 | Clusterin inhibits apoptosis by interacting with activated Bax |
| Q40020547 | Combined proteasome and Bcl-2 inhibition stimulates apoptosis and inhibits growth in EBV-transformed lymphocytes: a potential therapeutic approach to EBV-associated lymphoproliferative diseases |
| Q35906074 | Connecting proliferation and apoptosis in development and disease |
| Q47147815 | Curcumin Induces Apoptosis in EJ Bladder Cancer Cells via Modulating C-Myc and PI3K/Akt Signaling Pathway |
| Q34357003 | Cyr61 suppresses growth of human endometrial cancer cells |
| Q34330920 | Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria |
| Q33471086 | Cytotoxic Activities of Physalis minima L. Chloroform Extract on Human Lung Adenocarcinoma NCI-H23 Cell Lines by Induction of Apoptosis |
| Q39778382 | Different changes in protein and phosphoprotein levels result from serum starvation of high-grade glioma and adenocarcinoma cell lines |
| Q35128451 | Differential cooperation of oncogenes with p53 and Bax to induce apoptosis in rhabdomyosarcoma |
| Q37515926 | Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity. |
| Q45182291 | Distinct domains control the addressing and the insertion of Bax into mitochondria. |
| Q34897529 | Distinct thresholds govern Myc's biological output in vivo |
| Q47117102 | EBV and Apoptosis: The Viral Master Regulator of Cell Fate? |
| Q36525145 | Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth |
| Q33413336 | Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells |
| Q38525548 | Expression of HER-2 in MCF-7 breast cancer cells modulates anti-apoptotic proteins Survivin and Bcl-2 via the extracellular signal-related kinase (ERK) and phosphoinositide-3 kinase (PI3K) signalling pathways |
| Q36253591 | Functional analysis of the host defense peptide Human Beta Defensin-1: new insight into its potential role in cancer |
| Q41398406 | Gene Expression upon Proliferation and Differentiation of Hematopoietic Cells with Ph Chromosome ex vivo. |
| Q35905054 | Gfi/Pag-3/senseless zinc finger proteins: a unifying theme? |
| Q51797664 | Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects. |
| Q38283101 | JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression |
| Q38963730 | MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib |
| Q37732974 | MYC in oncogenesis and as a target for cancer therapies |
| Q33440553 | MYC prevents apoptosis and enhances endoreduplication induced by paclitaxel |
| Q40663259 | Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins. |
| Q38796781 | Molecular mechanism of apoptosis induction by Gaillardin, a sesquiterpene lactone, in breast cancer cell lines : Gaillardin-induced apoptosis in breast cancer cell lines. |
| Q33527429 | Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage |
| Q38568550 | Myc: the beauty and the beast |
| Q35150716 | Nonredundant role of Bax and Bak in Bid-mediated apoptosis |
| Q50754258 | Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt-Mdm2-p53 pathway. |
| Q40509976 | P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. |
| Q24792982 | PTTG/securin activates expression of p53 and modulates its function |
| Q38960311 | Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks. |
| Q40115861 | Platelet production from induced pluripotent stem cells |
| Q40394559 | Possible mechanism for hepatitis B virus X gene to induce apoptosis of hepatocytes |
| Q37420038 | Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival. |
| Q28284332 | Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4 |
| Q37333643 | Reflecting on 25 years with MYC. |
| Q54449175 | Sensitisation of c-MYC-induced B-lymphoma cells to apoptosis by ATF2. |
| Q46189582 | Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo |
| Q35537902 | The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth. |
| Q33360284 | The effect of targeted magnetic nanopaticles on hepatoma and the expression of bcl-2/bax protein |
| Q49806891 | The human T-cell leukemia virus type-1 p30II protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis |
| Q30494400 | The mechanism whereby heat shock induces apoptosis depends on the innate sensitivity of cells to stress |
| Q36288668 | Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition. |
| Q28205057 | c-MYC: more than just a matter of life and death |
| Q24653312 | c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL |
| Q38531621 | c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis |
| Q42157242 | c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade |
| Q35752871 | c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis |
| Q90797260 | c-Myc promotes tubular cell apoptosis in ischemia-reperfusion-induced renal injury by negatively regulating c-FLIP and enhancing FasL/Fas-mediated apoptosis pathway |
| Q51642930 | c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. |
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