Discordance between frequency of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-producing CD4(+) T cells and HIV-1-specific lymphoproliferation in HIV-1-infected subjects with active viral replication

scientific article published on June 2002

Discordance between frequency of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-producing CD4(+) T cells and HIV-1-specific lymphoproliferation in HIV-1-infected subjects with active viral replication is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.76.12.5925-5936.2002
P932PMC publication ID136191
P698PubMed publication ID12021325
P5875ResearchGate publication ID11351189

P2093author name stringC C Wilson
B E Palmer
E Boritz
N Blyveis
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High-level HIV-1 viremia suppresses viral antigen-specific CD4(+) T cell proliferationQ33950164
Programmed death of T cells in human immunodeficiency virus infection. No correlation with progression to diseaseQ34130886
Apoptotic cell death in the pathogenesis of infectious diseases.Q34361975
Lymphocyte proliferative responses to human immunodeficiency virus antigens in vitroQ34570241
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HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppressionQ43750477
Prolonged suppression of human immunodeficiency virus type 1 (HIV-1) viremia in persons with advanced disease results in enhancement of CD4 T cell reactivity to microbial antigens but not to HIV-1 antigens.Q43954731
Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315.Q44015315
Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin.Q44558202
Loss of CD4+ T cell proliferative ability but not loss of human immunodeficiency virus type 1 specificity equates with progression to diseaseQ45740979
Specific Th1 cytokine down-regulation associated with primary clinically derived human immunodeficiency virus type 1 Nef gene-induced expression.Q45771524
Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulationQ45877028
Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects.Q45940452
Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease.Q52026668
Early T-helper cell defects in HIV infection.Q52100356
Immune control of HIV-1 after early treatment of acute infectionQ56961920
Antigenic peptides recognized by T lymphocytes from AIDS viral envelope-immune humansQ59046097
Lack of T-cell proliferative response to HIV-1 antigens after 1 year of highly active antiretroviral treatment in early HIV-1 diseaseQ61767238
Programmed death of T cells in HIV-1 infectionQ67518695
Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognitionQ69383880
Selective CD4+ T cell deletion after specific activation in HIV-infected individuals; protection by anti-CD28 monoclonal antibodiesQ71233527
Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the DonorQ72059554
Downregulation of CD28 surface antigen on CD4+ and CD8+ T lymphocytes during HIV-1 infectionQ72668437
Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic responseQ73297445
Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV diseaseQ73470103
CD28 costimulation and T lymphocyte proliferative responses in HIV-1 infectionQ73781386
CD40 ligand trimer and IL-12 enhance peripheral blood mononuclear cells and CD4+ T cell proliferation and production of IFN-gamma in response to p24 antigen in HIV-infected individuals: potential contribution of anergy to HIV-specific unresponsiveneQ74027299
CD40 ligand and IFN-gamma synergistically restore IL-12 production in HIV-infected patientsQ74375686
Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infectionQ77324015
Lymphoproliferative response to HIV type 1 p24 in long-term survivors of HIV type 1 infection is predictive of persistent AIDS-free infectionQ78121234
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)5925-5936
P577publication date2002-06-01
P1433published inJournal of VirologyQ1251128
P1476titleDiscordance between frequency of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-producing CD4(+) T cells and HIV-1-specific lymphoproliferation in HIV-1-infected subjects with active viral replication
P478volume76

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