ExsB is required for correct assembly of the Pseudomonas aeruginosa type III secretion apparatus in the bacterial membrane and full virulence in vivo

scientific article published on 17 February 2015

ExsB is required for correct assembly of the Pseudomonas aeruginosa type III secretion apparatus in the bacterial membrane and full virulence in vivo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00048-15
P932PMC publication ID4399059
P698PubMed publication ID25690097
P5875ResearchGate publication ID272512907

P50authorSylvie ElsenQ59685039
Ina AttreeQ37840378
Philippe HuberQ41864406
P2093author name stringEric Faudry
Ariel Blocker
Stéphanie Bouillot
Caroline Perdu
P2860cites workReplication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in transQ24597491
Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughoutQ24644829
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PilF Is an Outer Membrane Lipoprotein Required for Multimerization and Localization of the Pseudomonas aeruginosa Type IV Pilus SecretinQ27652030
Structural characterization of the type-III pilot-secretin complex from Shigella flexneriQ27652595
Three-dimensional model of Salmonella's needle complex at subnanometer resolutionQ27666889
Structural characterization and membrane localization of ExsB from the type III secretion system (T3SS) of Pseudomonas aeruginosaQ27671710
Pilotin-secretin recognition in the type II secretion system of Klebsiella oxytocaQ27675649
Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspSQ27675923
Crystal structure of the pilotin from the enterohemorrhagic Escherichia coli type II secretion systemQ27676692
Structure and composition of the Shigella flexneri "needle complex", a part of its type III secretonQ28199735
HxcQ liposecretin is self-piloted to the outer membrane by its N-terminal lipid anchorQ28492860
ExsE, a secreted regulator of type III secretion genes in Pseudomonas aeruginosaQ28492983
PscF is a major component of the Pseudomonas aeruginosa type III secretion needleQ28493056
Functional mapping of PilF and PilQ in the Pseudomonas aeruginosa type IV pilus systemQ28493292
A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutantsQ29547327
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepaciaQ29615286
Outer membrane targeting of Pseudomonas aeruginosa proteins shows variable dependence on the components of Bam and Lol machineriesQ30155415
Lipoprotein sorting in bacteria.Q30155534
Deciphering the assembly of the Yersinia type III secretion injectisomeQ30494891
Injection of Pseudomonas aeruginosa Exo toxins into host cells can be modulated by host factors at the level of translocon assembly and/or activityQ31047709
The Salmonella typhimurium InvH protein is an outer membrane lipoprotein required for the proper localization of InvG.Q47782438
Functional characterization of the Erwinia chrysanthemi OutS protein, an element of a type II secretion systemQ48002970
An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosaQ48073553
Salmonella InvG forms a ring-like multimer that requires the InvH lipoprotein for outer membrane localizationQ50128955
Cockroaches as vectors of pathogenic bacteria.Q52454341
Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and functionQ64449370
Integration-proficient plasmids for Pseudomonas aeruginosa: site-specific integration and use for engineering of reporter and expression strainsQ73301855
A pilot sheds light on secretin assemblyQ79673565
Site-directed mutagenesis of the Pseudomonas aeruginosa type III secretion system protein PscJ reveals an essential role for surface-localized residues in needle complex functionQ81533314
The Pseudomonas aeruginosa opportunistic pathogen and human infectionsQ83748693
Differential habitat use and niche partitioning by Pseudomonas species in human homesQ33876648
Structure and biochemical analysis of a secretin pilot proteinQ33937224
Cochaperone interactions in export of the type III needle component PscF of Pseudomonas aeruginosaQ33963009
MxiM and MxiJ, base elements of the Mxi-Spa type III secretion system of Shigella, interact with and stabilize the MxiD secretin in the cell envelopeQ33997150
The human pathogen Pseudomonas aeruginosa utilizes conserved virulence pathways to infect the social amoeba Dictyostelium discoideumQ34016834
Structural and functional insights into the pilotin-secretin complex of the type II secretion systemQ34162292
Structure/function analysis of Neisseria meningitidis PilW, a conserved protein that plays multiple roles in type IV pilus biologyQ35139363
Secretins: dynamic channels for protein transport across membranesQ35163039
Structure and electrophysiological properties of the YscC secretin from the type III secretion system of Yersinia enterocoliticaQ35279783
VirG, a Yersinia enterocolitica lipoprotein involved in Ca2+ dependency, is related to exsB of Pseudomonas aeruginosaQ35590983
Functional analysis of exsC and exsB in regulation of exoenzyme S production by Pseudomonas aeruginosaQ35620604
ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival.Q35740028
Type III secretion systems and diseaseQ36969851
Structure and biophysics of type III secretion in bacteriaQ37014297
Pseudomonas aeruginosa - a phenomenon of bacterial resistanceQ37520253
The AlgZR two-component system recalibrates the RsmAYZ posttranscriptional regulatory system to inhibit expression of the Pseudomonas aeruginosa type III secretion system.Q37545976
Membrane targeting and pore formation by the type III secretion system transloconQ37823656
Decoding the roles of pilotins and accessory proteins in secretin escort servicesQ37958082
The C-terminal domain of the secretin PulD contains the binding site for its cognate chaperone, PulS, and confers PulS dependence on pIVf1 functionQ38346295
Role of the pilot protein YscW in the biogenesis of the YscC secretin in Yersinia enterocoliticaQ39247048
Cell death of human polymorphonuclear neutrophils induced by a Pseudomonas aeruginosa cystic fibrosis isolate requires a functional type III secretion systemQ39512990
BcsKC is an essential protein for the type VI secretion system activity in Burkholderia cenocepacia that forms an outer membrane complex with BcsLBQ39664786
Reduced apoptosis of mouse macrophages induced by yscW mutant of Yersinia pestis results from the reduced secretion of YopJ and relates to caspase-3 signal pathwayQ39800030
Biological and genetic characterization of TnphoA mutants of Salmonella typhimurium TML in the context of gastroenteritisQ39821358
Characterization of intestinal invasion by Salmonella typhimurium and Salmonella dublin and effect of a mutation in the invH gene.Q39822503
Agricultural plants and soil as a reservoir for Pseudomonas aeruginosaQ39861821
Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infectionsQ40706274
Pore-forming activity of type III system-secreted proteins leads to oncosis of Pseudomonas aeruginosa-infected macrophagesQ40813368
The V antigen of Pseudomonas aeruginosa is required for assembly of the functional PopB/PopD translocation pore in host cell membranesQ41195095
Secrets of a secretinQ41391250
Structure of the dodecameric Yersinia enterocolitica secretin YscC and its trypsin-resistant core.Q41392018
The assembly of the export apparatus (YscR,S,T,U,V) of the Yersinia type III secretion apparatus occurs independently of other structural components and involves the formation of an YscV oligomer.Q41425944
Protective anti-V antibodies inhibit Pseudomonas and Yersinia translocon assembly within host membranesQ41458033
The outer membrane component, YscC, of the Yop secretion machinery of Yersinia enterocolitica forms a ring-shaped multimeric complexQ41487131
Anti-activator ExsD forms a 1:1 complex with ExsA to inhibit transcription of type III secretion operons.Q43096524
Deletion of invH gene in Salmonella enterica serovar Typhimurium limits the secretion of Sip effector proteinsQ43490328
Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa.Q44912919
Sequential inactivation of Rho GTPases and Lim kinase by Pseudomonas aeruginosa toxins ExoS and ExoT leads to endothelial monolayer breakdownQ47708196
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
P304page(s)1789-1798
P577publication date2015-02-17
P1433published inInfection and ImmunityQ6029193
P1476titleExsB is required for correct assembly of the Pseudomonas aeruginosa type III secretion apparatus in the bacterial membrane and full virulence in vivo
P478volume83

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cites work (P2860)
Q89535076Bacterial secretins: Mechanisms of assembly and membrane targeting
Q64109764Correct Sorting of Lipoproteins into the Inner and Outer Membranes of Pseudomonas aeruginosa by the Escherichia coli LolCDE Transport System
Q50197698Defining Lipoprotein Localisation by Fluorescence Microscopy
Q35913819Identification of YsaP, the Pilotin of the Yersinia enterocolitica Ysa Type III Secretion System
Q90170341On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome
Q40777839Phenotype and toxicity of the recently discovered exlA-positive Pseudomonas aeruginosa strains collected worldwide.
Q64102270Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of

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