Activation of the interferon response by human cytomegalovirus occurs via cytoplasmic double-stranded DNA but not glycoprotein B. (scientific article published on 23 June 2010)

Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs

Q24311713

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

Q24315639

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

Q24317317

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Q24317784

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Q24318426

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Q24336255

Innate immune recognition of viral infection

Q24498364

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

Q24523761

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

Q24533140

Antiviral actions of interferons

Q24550676

Innate cellular response to virus particle entry requires IRF3 but not virus replication

Q24607212

The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes

Q24607496

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

Q24634416

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Q25938999

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Q27860685

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

Q27861007

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

Q27861127

5'-Triphosphate RNA is the ligand for RIG-I

Q28131726

VISA is an adapter protein required for virus-triggered IFN-beta signaling

Q28131814

Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3

Q28141455

Cytomegalovirus infections in transplant patients.

Q41154225

STAT-1- and IRF-3-dependent pathways are not essential for repression of ICP0-null mutant herpes simplex virus type 1 in human fibroblasts

Q42064424

A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon

Q42096820

Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

Q42810400

Interferon regulatory factor 3 is necessary for induction of antiviral genes during human cytomegalovirus infection

Q43181876

Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling

Q44318736

Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription

Q44445912

Roles of an IkappaB kinase-related pathway in human cytomegalovirus-infected vascular smooth muscle cells: a molecular link in pathogen-induced proatherosclerotic conditions.

Q45201933

The IFN-independent response to virus particle entry provides a first line of antiviral defense that is independent of TLRs and retinoic acid-inducible gene I.

Q45409957

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

Q54631516

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

Q28190704

Triggering the interferon antiviral response through an IKK-related pathway

Q28191761

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

Q28609049

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

Q29615913

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

Q29616156

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

Q29620054

ZBP1 subcellular localization and association with stress granules is controlled by its Z-DNA binding domains

Q30478275

Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1.

Q33558664

Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts

Q33787378

Herpes simplex virus triggers and then disarms a host antiviral response

Q33835458

Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs

Q33870381

Engagement of the cellular receptor for glycoprotein B of human cytomegalovirus activates the interferon-responsive pathway

Q33957986

IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA

Q34029053

Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

Q34365709

Do pathogens accelerate atherosclerosis?

Q34389205

A human cytomegalovirus antagonist of type I IFN-dependent signal transducer and activator of transcription signaling

Q34944144

The host type I interferon response to viral and bacterial infections

Q36178864

A mutant cell line defective in response to double-stranded RNA and in regulating basal expression of interferon-stimulated genes

Q36260813

Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B.

Q36295396

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

Q36535512

Antiviral signaling through pattern recognition receptors

Q36693188

Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays

Q36736217

Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity.

Q36742231

Human cytomegalovirus glycoprotein B is required for virus entry and cell-to-cell spread but not for virion attachment, assembly, or egress

Q37145274

Congenital and perinatal cytomegalovirus infections

Q37897929

Kaposi's sarcoma-associated herpesvirus virions inhibit interferon responses induced by envelope glycoprotein gpK8.1.

Q39305101

Cytomegalovirus activates interferon immediate-early response gene expression and an interferon regulatory factor 3-containing interferon-stimulated response element-binding complex

Q39575110

Activation of interferon response factor-3 in human cells infected with herpes simplex virus type 1 or human cytomegalovirus

Q39603963

Infection with herpes simplex type 1-based amplicon vectors results in an IRF3/7-dependent, TLR-independent activation of the innate antiviral response in primary human fibroblasts

Q39839678

Characterization of the interferon regulatory factor 3-mediated antiviral response in a cell line deficient for IFN production

Q39911431

Glycoprotein-dependent and TLR2-independent innate immune recognition of herpes simplex virus-1 by dendritic cells.

Q39980568

Differential initiation of innate immune responses induced by human cytomegalovirus entry into fibroblast cells

Q40000308

Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression

Q40130383

EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN.

Q40237206

Identification of a novel pathway essential for the immediate-early, interferon-independent antiviral response to enveloped virions

Q40340459

Interaction between the human cytomegalovirus UL82 gene product (pp71) and hDaxx regulates immediate-early gene expression and viral replication

Q40416407

Human cytomegalovirus elicits a coordinated cellular antiviral response via envelope glycoprotein B.

Q40468638

Vesicular stomatitis virus and pseudorabies virus induce a vig1/cig5 homologue in mouse dendritic cells via different pathways.

Q40847997

Postattachment events associated with viral entry are necessary for induction of interferon-stimulated genes by human cytomegalovirus

Q40887036

Induction of interferon-alpha by glycoprotein D of herpes simplex virus: a possible role of chemokine receptors

Q40990994

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

Cytomegalovirus

Q6946

P304

page(s)

8913-8925

P577

publication date

2010-06-23

P1433

published in

Journal of Virology

Q1251128

P1476

title

Activation of the interferon response by human cytomegalovirus occurs via cytoplasmic double-stranded DNA but not glycoprotein B.

P478

volume

Reverse relations

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P356	DOI	10.1128/JVI.00169-10
P8608	Fatcat ID	release_pfmdrgu6gbe23hl4bhpv34xqq4
P932	PMC publication ID	2919031
P698	PubMed publication ID	20573816