Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor by promoting angiogenesis

scientific article published on July 2010

Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor by promoting angiogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EJI.200940157
P8608Fatcat IDrelease_nkxmdym3ffftjcmawrlft4jndy
P698PubMed publication ID20397212
P5875ResearchGate publication ID43161698

P50authorYoichiro IwakuraQ56564114
P2093author name stringKenji Chamoto
Takashi Nishimura
Hiroyoshi Nishikawa
Takayuki Ohkuri
Hidemitsu Kitamura
Daiko Wakita
Kentaro Sumida
P2860cites workThe biological functions of T helper 17 cell effector cytokines in inflammationQ24614431
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responsesQ24630221
T helper 17 cells promote cytotoxic T cell activation in tumor immunityQ24646584
Tumor-specific Th17-polarized cells eradicate large established melanomaQ24648032
Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesisQ60241749
CCR6 and NK1.1 distinguish between IL-17A and IFN-γ-producing γδ effector T cellsQ60709864
Expression of IL-17 mRNA in ovarian cancerQ74008184
Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cellsQ82930126
Cancer-related inflammationQ27860907
Regulation of cutaneous malignancy by gammadelta T cellsQ28188439
IL-23 promotes tumour incidence and growthQ28239522
Interferons, immunity and cancer immunoeditingQ28270336
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
Antagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesisQ28681056
Paradoxical roles of the immune system during cancer developmentQ29614305
Immunosuppressive networks in the tumour environment and their therapeutic relevanceQ29619244
Angiogenesis as a therapeutic targetQ29619525
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicityQ29620119
Immune Enhancement of Skin Carcinogenesis by CD4+ T CellsQ33186709
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defenseQ34087551
CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsetsQ34205998
An essential role of antigen-presenting cell/T-helper type 1 cell-cell interactions in draining lymph node during complete eradication of class II-negative tumor tissue by T-helper type 1 cell therapyQ34490538
Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancerQ34843832
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environmentsQ34983123
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathwayQ34989745
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophagesQ34995099
Characterizing tumor-promoting T cells in chemically induced cutaneous carcinogenesisQ35800371
The critical role of type-1 innate and acquired immunity in tumor immunotherapyQ35911850
Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia.Q36229379
Gamma delta T cells provide an early source of interferon gamma in tumor immunityQ36371404
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancerQ36371644
Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivoQ36375248
Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironmentQ36850206
Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17Q36981811
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironmentQ37169987
Type 17 CD8+ T cells display enhanced antitumor immunity.Q37268980
IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cellsQ38271046
Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathwayQ40101993
Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironmentQ40130406
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesisQ40360012
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signalsQ43291519
Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responsesQ44158655
IFN-gamma-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model.Q45976146
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.Q46815296
Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs.Q53580983
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.Q53597450
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
P304page(s)1927-1937
P577publication date2010-07-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleTumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor by promoting angiogenesis
P478volume40

Reverse relations

cites work (P2860)
Q41699485Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells
Q36059097Association of γδ T Cell Compartment Size to Disease Activity and Response to Therapy in SLE.
Q92853203CAR-Based Strategies beyond T Lymphocytes: Integrative Opportunities for Cancer Adoptive Immunotherapy
Q56896815CTLA-4 (CD152) enhances the Tc17 differentiation program
Q97653023Cancer immunotherapy with γδ T cells: many paths ahead of us
Q88215974Characteristics of γδ T cells in Schistosoma japonicum-infected mouse mesenteric lymph nodes
Q36038030Characterization and Clinical Implication of Th1/Th2/Th17 Cytokines Produced from Three-Dimensionally Cultured Tumor Tissues Resected from Breast Cancer Patients
Q27025504Close link between development and function of gamma-delta T cells
Q36444174Complex role of γδ T-cell-derived cytokines and growth factors in cancer
Q42480340Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial γδ T cells is functional in vivo.
Q55012882Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy.
Q26863724Direct and Indirect Effects of Cytomegalovirus-Induced γδ T Cells after Kidney Transplantation
Q27010199Diversity of IL-17-producing T lymphocytes
Q84007852Driving IL-17⁺ γδ T-cell migration in allergic reactions: a new "inflammatory" role for the "homeostatic" chemokine CCL25
Q37581683Effect of IL-17 in the development of colon cancer in mice
Q26781175Empowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy
Q64057109Ex Vivo Expanded Human Vγ9Vδ2 T-Cells Can Suppress Epithelial Ovarian Cancer Cell Growth
Q59800422Extracellular Vesicle-Mediated Immune Regulation of Tissue Remodeling and Angiogenesis After Myocardial Infarction
Q39032098Formyl peptide receptor suppresses melanoma development and promotes NK cell migration
Q102059535Functional and metabolic dichotomy of murine γδ T cell subsets in cancer immunity
Q47742552Gamma-delta (γδ) T cells: friend or foe in cancer development?
Q27026048Genetic requirements for the development and differentiation of interleukin-17-producing γδ T cells
Q50872714High density of IL-17-producing cells is associated with improved prognosis for advanced epithelial ovarian cancer.
Q41866168Hmgb1-IL-23-IL-17-IL-6-Stat3 axis promotes tumor growth in murine models of melanoma
Q47599510Human papillomavirus oncoproteins induce a reorganization of epithelial-associated γδ T cells promoting tumor formation
Q37714642Human γδT-cell subsets and their involvement in tumor immunity.
Q37937750IFN-γ, IL-17 and TGF-β involvement in shaping the tumor microenvironment: The significance of modulating such cytokines in treating malignant solid tumors.
Q38256438IL-17 Expression by macrophages is associated with proliferative inflammatory atrophy lesions in prostate cancer patients
Q59808760IL-17 in Peritoneal Dialysis-Associated Inflammation and Angiogenesis: Conclusions and Perspectives
Q39616587IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guérin treatment against bladder cancer
Q38040747IL-23: one cytokine in control of autoimmunity
Q39016421IL-7 receptor blockade inhibits IL-17-producing γδ cells and suppresses melanoma development
Q40808689IL17 producing γδT cells induce angiogenesis and are associated with poor survival in gallbladder cancer patients
Q48128395Immune cells regulate VEGF signalling via release of VEGF and antagonistic soluble VEGF receptor-1.
Q38599837Immunity and immune modulation in Trypanosoma cruzi infection
Q42357971Immunosuppressive γδ T cells foster pancreatic carcinogenesis
Q55311835Improving the Efficiency of Vγ9Vδ2 T-Cell Immunotherapy in Cancer.
Q34570874Inhibition of IL-17A in tumor microenvironment augments cytotoxicity of tumor-infiltrating lymphocytes in tumor-bearing mice
Q37031654Interleukin-17 and type 17 helper T cells in cancer management and research
Q38390943Interleukin-17 is a favorable prognostic marker for colorectal cancer
Q62936781Interleukin-Mediated Pendrin Transcriptional Regulation in Airway and Esophageal Epithelia
Q36269037Langerhans Cells Facilitate UVB-Induced Epidermal Carcinogenesis
Q39337563Lung-resident γδ T cells and their roles in lung diseases
Q38173753Molecular Mechanisms of Differentiation of Murine Pro-Inflammatory γδ T Cell Subsets
Q34119854Murine CD27(-) Vγ6(+) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages
Q98280908Myeloid-derived suppressor cell depletion therapy targets IL-17A-expressing mammary carcinomas
Q40994227Nitric oxide synthase 2 is involved in the pro-tumorigenic potential of γδ17 T cells in melanoma
Q33810570Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia
Q34222410Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation
Q38998175Platelet factor 4 inhibits IL-17/Stat3 pathway via upregulation of SOCS3 expression in melanoma
Q57300020Positive & Negative Roles of Innate Effector Cells in Controlling Cancer Progression
Q84409413Promoting angiogenesis within the tumor microenvironment: the secret life of murine lymphoid IL-17-producing gammadelta T cells
Q41475326RORγt-expressing cells attenuate cardiac remodeling after myocardial infarction
Q36917913Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Q38787725Regulatory and effector functions of gamma-delta (γδ) T cells and their therapeutic potential in adoptive cellular therapy for cancer
Q88008277Regulatory functions of γδ T cells
Q27010451Six-of-the-best: unique contributions of γδ T cells to immunology
Q35944713Th17 and non-Th17 interleukin-17-expressing cells in chronic lymphocytic leukemia: delineation, distribution, and clinical relevance
Q34913808Th17 cells in cancer: help or hindrance?
Q37706556Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC.
Q38362640The Jekyll and Hyde story of IL17-Producing γδT Cells
Q57816901The Role of the Extracellular Matrix and Its Molecular and Cellular Regulators in Cancer Cell Plasticity
Q53164307The development of IL-17/IFN-γ-double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter.
Q92628379The features of circulating and tumor-infiltrating γδ T cells in melanoma patients display critical perturbations with prognostic impact on clinical outcome
Q84975992The parallel lives of angiogenesis and immunosuppression: cancer and other tales
Q38238738The role of interleukin 17 in tumour proliferation, angiogenesis, and metastasis.
Q38039112The split nature of tumor-infiltrating leukocytes: Implications for cancer surveillance and immunotherapy
Q38101567The tumor microenvironment: a pitch for multiple players.
Q93162748Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
Q38287973Tumor-Infiltrating γδ T Lymphocytes: Pathogenic Role, Clinical Significance, and Differential Programing in the Tumor Microenvironment.
Q55044228Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress.
Q28674494U87MG glioma cells overexpressing IL-17 acclerate early-stage growth in vivo and cause a higher level of CD31 mRNA expression in tumor tissues
Q38271584γδ T Cell-Mediated Immune Responses in Disease and Therapy
Q54326921γδ T Cells: Unexpected Regulators of Cancer Development and Progression.
Q38633738γδ T cell-based anticancer immunotherapy: progress and possibilities
Q38602555γδ T cells in cancer
Q90783584γδ T cells in cancer: a small population of lymphocytes with big implications
Q92826000γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer
Q38718920γδT Cells and Related Diseases
Q36473289γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer.
Q50088026γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program

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