Rapid generation of a well-matched vaccine seed from a modern influenza A virus primary isolate without recourse to eggs.

scientific article

Rapid generation of a well-matched vaccine seed from a modern influenza A virus primary isolate without recourse to eggs. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2010.02.012
P698PubMed publication ID20188682
P5875ResearchGate publication ID41621269

P50authorWendy BarclayQ20005716
Olivier MoncorgéQ55743797
P2093author name stringJ Ellis
J Goudsmit
C McLeod
C Bull
C I Thompson
W Koudstaal
L C S Hartgroves
M J E Havenga
P2860cites workGeneration of influenza A viruses entirely from cloned cDNAsQ29616768
Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans.Q30327772
The human cell line PER.C6 provides a new manufacturing system for the production of influenza vaccines.Q30328006
Expression and purification of an influenza hemagglutinin--one step closer to a recombinant protein-based influenza vaccine.Q30351951
The development and characterization of H5 influenza virus vaccines derived from a 2003 human isolate.Q30352362
Cross-reactive neuraminidase antibodies afford partial protection against H5N1 in mice and are present in unexposed humans.Q30359842
Enhanced growth of seed viruses for H5N1 influenza vaccinesQ30363037
Suitability of PER.C6 cells to generate epidemic and pandemic influenza vaccine strains by reverse genetics.Q30376923
Generation of candidate human influenza vaccine strains in cell culture - rehearsing the European response to an H7N1 pandemic threatQ30376964
Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitorsQ30452892
Heterosubtype neutralizing responses to influenza A (H5N1) viruses are mediated by antibodies to virus haemagglutininQ30913948
Balanced hemagglutinin and neuraminidase activities are critical for efficient replication of influenza A virusQ33806746
Functional balance between haemagglutinin and neuraminidase in influenza virus infectionsQ34126466
NS1 proteins of avian influenza A viruses can act as antagonists of the human alpha/beta interferon response.Q35784659
Selection of a single amino acid substitution in the hemagglutinin molecule by chicken eggs can render influenza A virus (H3) candidate vaccine ineffectiveQ35844791
MDCK-SIAT1 cells show improved isolation rates for recent human influenza viruses compared to conventional MDCK cellsQ36747588
Current challenges in implementing cell-derived influenza vaccines: implications for production and regulation, July 2007, NIBSC, Potters Bar, UK.Q37444287
Receptor binding specificity of recent human H3N2 influenza virusesQ38301903
Receptor-binding properties of modern human influenza viruses primarily isolated in Vero and MDCK cells and chicken embryonated eggsQ38350824
Stabilizing the glycosylation pattern of influenza B hemagglutinin following adaptation to growth in eggsQ40035682
A new approach to an influenza live vaccine: modification of the cleavage site of hemagglutininQ40415552
The growth of attenuated influenza vaccine donor strains in continuous cell lines.Q40476941
Changes in in vitro susceptibility of influenza A H3N2 viruses to a neuraminidase inhibitor drug during evolution in the human hostQ40577158
Hemagglutinin residues of recent human A(H3N2) influenza viruses that contribute to the inability to agglutinate chicken erythrocytesQ40774660
Development of a mammalian cell (Vero) derived candidate influenza virus vaccineQ41021315
Recombinant influenza A virus vaccines for the pathogenic human A/Hong Kong/97 (H5N1) virusesQ41643902
Improvement of influenza A/Fujian/411/02 (H3N2) virus growth in embryonated chicken eggs by balancing the hemagglutinin and neuraminidase activities, using reverse geneticsQ42755170
Single amino acid substitutions in the hemagglutinin of influenza A/Singapore/21/04 (H3N2) increase virus growth in embryonated chicken eggsQ45414991
Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics.Q45729695
Evidence for host-cell selection of influenza virus antigenic variantsQ45804806
Safety and immunogenicity of a new influenza vaccine grown in mammalian cell cultureQ47773239
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)2973-2979
P577publication date2010-02-25
P1433published inVaccineQ7907941
P1476titleRapid generation of a well-matched vaccine seed from a modern influenza A virus primary isolate without recourse to eggs
P478volume28

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cites work (P2860)
Q45325112A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 influenza A Virus in Cells
Q45778868A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
Q28084739Cell culture-based influenza vaccines: A necessary and indispensable investment for the future
Q35706440Error-prone pcr-based mutagenesis strategy for rapidly generating high-yield influenza vaccine candidates.
Q39585445Plaque purification as a method to mitigate the risk of adventitious-agent contamination in influenza vaccine virus seeds
Q92450354Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility
Q90000054Systematic evaluation of suspension MDCK cells, adherent MDCK cells, and LLC-MK2 cells for preparing influenza vaccine seed virus

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