Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

scientific article

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKG393
P932PMC publication ID156727
P698PubMed publication ID12771196
P5875ResearchGate publication ID277457311

P2093author name stringGijsbertus J Pronk
Anke Klippel
Jörg Kaufmann
Klaus Giese
Hüseyin Aygün
Frank Czauderna
Melanie Fechtner
Sibylle Dames
P2860cites workStable suppression of gene expression by RNAi in mammalian cellsQ24533429
Stabilizing effects of the RNA 2'-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2'-O-methylated adenosinesQ27748024
RNA interference is mediated by 21- and 22-nucleotide RNAsQ27860764
Role for a bidentate ribonuclease in the initiation step of RNA interferenceQ27860832
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansQ27860867
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsQ27860926
RNA interferenceQ28131798
Single-stranded antisense siRNAs guide target RNA cleavage in RNAiQ28201784
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAiQ28218870
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysateQ28365532
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cellsQ29547714
ATP requirements and small interfering RNA structure in the RNA interference pathwayQ29618384
Argonaute2, a link between genetic and biochemical analyses of RNAiQ29618385
Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.Q33951914
Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.Q34459792
Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapyQ35679433
The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activityQ36745695
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue FactorQ39597818
Tolerance for mutations and chemical modifications in a siRNA.Q39698017
GeneBlocs are powerful tools to study and delineate signal transduction processes that regulate cell growth and transformationQ40712978
PKR--a protein kinase regulated by double-stranded RNA.Q41647401
Establishment and maintenance of a heterochromatin domainQ44128134
RNAi in human cells: basic structural and functional features of small interfering RNA.Q44199577
Short 5'-phosphorylated double-stranded RNAs induce RNA interference in Drosophila.Q52592619
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.Q52600395
Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistanceQ71823724
Metabolism of antisense oligonucleotides in rat liver homogenatesQ73289482
Expanding small RNA interferenceQ78021693
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)2705-2716
P577publication date2003-06-01
P1433published inNucleic Acids ResearchQ135122
P1476titleStructural variations and stabilising modifications of synthetic siRNAs in mammalian cells
P478volume31

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