miRNA-Based Therapeutic Strategies

scientific article published on 24 December 2012

miRNA-Based Therapeutic Strategies is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1012822491
P356DOI10.1007/S40139-012-0004-5
P932PMC publication ID3601800
P698PubMed publication ID23524956
P5875ResearchGate publication ID236076791

P2093author name stringFlorin M Selaru
Masaharu Ishida
P2860cites workExportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAsQ24302072
MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansionQ24305799
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencingQ24537549
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cellsQ24596316
Efficient inhibition of miR-155 function in vivo by peptide nucleic acidsQ24603017
MicroRNAs: target recognition and regulatory functionsQ24609584
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44Q24617130
Regression of murine lung tumors by the let-7 microRNAQ24621218
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genesQ24628676
Downregulation of miR-122 in the rodent and human hepatocellular carcinomasQ24631076
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosisQ24634165
MicroRNA biogenesis: there's more than one way to skin a catQ24642062
MicroRNA let-7: an emerging next-generation cancer therapeuticQ24644251
MicroRNA expression, survival, and response to interferon in liver cancerQ24647241
Suppression of non-small cell lung tumor development by the let-7 microRNA familyQ24651985
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer modelQ24655262
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progressionQ24681466
Oncomirs - microRNAs with a role in cancerQ27860773
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Q27860849
Silencing of microRNAs in vivo with 'antagomirs'Q27860891
Processing of primary microRNAs by the Microprocessor complexQ27860986
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNAQ27861124
Single-stranded antisense siRNAs guide target RNA cleavage in RNAiQ28201784
MicroRNA-26a promotes cholangiocarcinoma growth by activating β-cateninQ28263940
The let-7 microRNA reduces tumor growth in mouse models of lung cancerQ28272817
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34Q28285980
The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activitiesQ28297958
MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitroQ28299575
MicroRNAs as therapeutic targetsQ28302308
MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasisQ28509140
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblastsQ28511032
miR-122 regulation of lipid metabolism revealed by in vivo antisense targetingQ29547487
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancerQ29547523
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infectionQ29615959
LNA-mediated microRNA silencing in non-human primatesQ29615962
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathwaysQ29618467
microRNA-34a is tumor suppressive in brain tumors and glioma stem cellsQ30428366
A simple Bayesian estimate of direct RNAi gene regulation events from differential gene expression profilesQ31012608
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIMQ33336561
MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2.Q33564111
MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity.Q33575825
Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorshipQ33719798
RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAsQ33721873
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressorsQ33755320
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo.Q33913718
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosisQ34044475
MicroRNA delivery by cationic lipoplexes for lung cancer therapyQ34060310
MicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5Q34123881
MicroRNA sponges: progress and possibilitiesQ34139023
Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancerQ34248844
Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21.Q34271727
Evolutionary conservation of microRNA regulatory circuits: an examination of microRNA gene complexity and conserved microRNA-target interactions through metazoan phylogenyQ34623669
Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapyQ34915120
Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growthQ35029501
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in miceQ35086711
MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia.Q35659883
MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cellsQ35668910
miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells.Q35889599
Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA.Q35902685
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesisQ36129123
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver.Q36129129
Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinomaQ36130078
Silencing of microRNA families by seed-targeting tiny LNAsQ36522844
Potent and nontoxic antisense oligonucleotides containing locked nucleic acidsQ36985622
Advances in microRNAs: implications for gene therapistsQ37037641
Potent inhibition of microRNA in vivo without degradationQ37041859
RNAs as extracellular signaling moleculesQ37121371
Cancerous miRNAs and their regulationQ37158988
Knocking down barriers: advances in siRNA deliveryQ37380671
Developing therapeutic microRNAs for cancerQ37543146
Self-assembled RNA interference microsponges for efficient siRNA deliveryQ37662457
MicroRNAs and the cell cycleQ37840505
Clinical potential of microRNAs in pancreatic ductal adenocarcinoma.Q37946163
Subcellular fate and off-target effects of siRNA, shRNA, and miRNA.Q37950261
Developing microRNA therapeuticsQ37981141
MicroRNAs as therapeutic targets and their potential applications in cancer therapyQ38018097
The principles of MiRNA-masking antisense oligonucleotides technologyQ38340276
Anti-miR-21 oligonucleotide enhances chemosensitivity of leukemic HL60 cells to arabinosylcytosine by inducing apoptosisQ38342043
MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells.Q39321003
MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancerQ39371738
MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/β-catenin pathwayQ39406412
The proto-oncogene Pim-1 is a target of miR-33aQ39509450
Downregulation of Spry2 by miR-21 triggers malignancy in human gliomasQ39600647
MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumabQ39609757
Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cells.Q39627053
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cellsQ39758746
MicroRNA-101 exerts tumor-suppressive functions in non-small cell lung cancer through directly targeting enhancer of zeste homolog 2.Q39789409
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomasQ40073679
siRNA function in RNAi: a chemical modification analysisQ42044356
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAsQ45147309
MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN proteinQ82270543
Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2Q84281961
P433issue1
P304page(s)63-70
P577publication date2012-12-24
P1433published inCurrent anesthesiology reportsQ26842367
P1476titlemiRNA-Based Therapeutic Strategies
P478volume1

Reverse relations

cites work (P2860)
Q34157812Aberrantly up-regulated miR-20a in pre-eclampsic placenta compromised the proliferative and invasive behaviors of trophoblast cells by targeting forkhead box protein A1.
Q27001694Cholangiocarcinoma
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Q47361566Effects of the antagomiRs 15b and 200b on the altered healing pattern of diabetic mice
Q48529755Function of miR-146a-5p in Tumor Cells As a Regulatory Switch between Cell Death and Angiogenesis: Macrophage Therapy Revisited
Q35653311Mechanisms of thrombosis in obesity
Q49917036MicroRNA Replacement: A New Era of Molecular Therapy for Tendon Disorders?
Q64963896MicroRNA-153 promotes brain-derived neurotrophic factor and hippocampal neuron proliferation to alleviate autism symptoms through inhibition of JAK-STAT pathway by LEPR.
Q37029400MicroRNA-208b Alleviates Post-Infarction Myocardial Fibrosis in a Rat Model by Inhibiting GATA4.
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Q64859159Signature of Aberrantly Expressed microRNAs in the Striatum of Rotenone-Induced Parkinsonian Rats
Q48611625TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis.
Q37691772The role of microRNAs in skin fibrosis.
Q26774954To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAs
Q38138933miR in melanoma development: miRNAs and acquired hallmarks of cancer in melanoma.
Q40660140miRegulome: a knowledge-base of miRNA regulomics and analysis.
Q35193913mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice

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