Cellular and molecular mechanisms of endothelial cell dysfunction

scientific article published on November 1997

Cellular and molecular mechanisms of endothelial cell dysfunction is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI119751
P932PMC publication ID508409
P698PubMed publication ID9410891

P2093author name stringHarrison DG
P2860cites workCytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cellsQ28290518
p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cellsQ28572118
Up‐regulation of endothelial nitric oxide synthase expression by cyclic guanosine 3′,5′‐monophosphateQ30464214
Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthaseQ31172360
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginineQ33882001
Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-toleranceQ34194262
Regulation of G-protein alpha i2 subunit expression by oxidized low-density lipoproteinQ34206300
Interactions between L-arginine and L-glutamine change endothelial NO production. An effect independent of NO synthase substrate availability.Q34223377
Kinetics of cytochrome c2+ oxidation by peroxynitrite: implications for superoxide measurements in nitric oxide-producing biological systemsQ34313420
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor toneQ34378188
p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive ratsQ34411966
Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertensionQ34415739
Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patientsQ34440940
Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5'-monophosphate formation in atherosclerotic human coronary artery and rabbit aortaQ34555162
L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humansQ35606367
Cyclic strain upregulates nitric oxide synthase in cultured bovine aortic endothelial cellsQ35763125
Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aortaQ35818430
Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbitQ35822869
Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drugQ37359995
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.Q37362273
The vascular effects of L-Arginine in humans. The role of endogenous insulinQ37363072
Nitric oxide synthases: which, where, how, and why?Q37374087
Superoxide and peroxynitrite in atherosclerosisQ37558573
The endothelial cell nitric oxide synthase: is it really constitutively expressed?Q40399670
L-arginine does not restore endothelial dysfunction in atherosclerotic rabbit aorta in vitro.Q41165271
Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbitsQ41169284
Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthasesQ41215964
Role of the enzyme calmodulin-binding domain in membrane association and phospholipid inhibition of endothelial nitric oxide synthaseQ41334662
Endothelial control of vasomotion and nitric oxide production: a potential target for risk factor managementQ41386323
Generation of superoxide by purified brain nitric oxide synthaseQ41590269
Low concentration of oxidized low-density lipoprotein and lysophosphatidylcholine upregulate constitutive nitric oxide synthase mRNA expression in bovine aortic endothelial cellsQ41665885
Lack of evidence for linkage of the endothelial cell nitric oxide synthase gene to essential hypertensionQ42476818
An NADPH oxidase superoxide-generating system in the rabbit aortaQ42480478
NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endotheliumQ42495148
Activation of L-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells.Q42519401
Regulation of L-arginine transport and nitric oxide release in superfused porcine aortic endothelial cellsQ42521287
Loss of endothelial pertussis toxin-sensitive G protein function in atherosclerotic porcine coronary arteriesQ44026838
Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aortaQ44068968
Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO productionQ46641954
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failureQ46861533
Properties of a superoxide anion-generating microsomal NADH oxidoreductase, a potential pulmonary artery PO2 sensor.Q50767301
NADPH oxidase of human neutrophils. Subcellular localization and characterization of an arachidonate-activatable superoxide-generating system.Q52489900
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.Q54225996
L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits.Q54310603
Cytokines regulate endotoxin stimulation of endothelial cell arginine transport.Q54617709
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cellsQ63365807
Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginineQ68326802
Role of cytochrome b-559 in arachidonic acid activation of resting human neutrophilsQ69840367
Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expressionQ71607436
Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholineQ71702928
Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stressQ71720438
Selective induction of a cationic amino acid transporter by tumor necrosis factor-alpha in vascular endotheliumQ71747946
Antioxidative Activity of 5,6,7,8-Tetrahydrobiopterin and its Inhibitory Effect on Paraquat-Induced Cell Toxicity in Cultured Rat HepatocytesQ71795059
Antioxidant vitamin C improves endothelial dysfunction in chronic smokersQ71884045
Amelioration by L-arginine of a dysfunctional arginine/nitric oxide pathway in diabetic endotheliumQ72285314
Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscleQ72383072
Endothelial Gi protein in human coronary arteriesQ72862370
Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterinQ73010911
Association analysis of CA repeat polymorphism of the endothelial nitric oxide synthase gene with essential hypertension in JapaneseQ73186362
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive diseaseQ73303024
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
P304page(s)2153-2157
P577publication date1997-11-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleCellular and molecular mechanisms of endothelial cell dysfunction
P478volume100

Reverse relations

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