Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase

scientific article

Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKG672
P932PMC publication ID169932
P698PubMed publication ID12907738
P5875ResearchGate publication ID10621941

P50authorDaniel GarinQ89768660
Natale ScaramozzinoQ90663867
Robert DrillienQ115100899
P2093author name stringBodil Kavli
Jacques Laval
Murat Saparbaev
Jean Marc Crance
Guenhael Sanz
P2860cites workExcision of uracil residues in DNA: mechanism of action of Escherichia coli and Micrococcus luteus uracil-DNA glycosylasesQ40567747
The vaccinia virus-encoded uracil DNA glycosylase has an essential role in viral DNA replicationQ42611852
Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D regionQ42631983
The complete DNA sequence of vaccinia virusQ42634066
Expression of a uracil DNA glycosylase (UNG) inhibitor in mammalian cells: varicella-zoster virus can replicate in vitro in the absence of detectable UNG activityQ45752555
Gene UL2 of herpes simplex virus type 1 encodes a uracil-DNA glycosylaseQ45844610
Containing bioterrorist smallpox.Q52028448
Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.Q54097863
Complications of smallpox vaccination, 1968.Q54142563
Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA GlycosylaseQ57942555
Heat-induced deamination of cytosine residues in deoxyribonucleic acidQ69352442
Stimulation of the nuclear uracil DNA glycosylase in proliferating human fibroblastsQ70822038
The threat of smallpox and bioterrorismQ73413051
Smallpox as a Biological WeaponQ22918878
hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backupQ24303661
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG geneQ24317201
Post-replicative base excision repair in replication fociQ24534209
Bioterrorism: implications for the clinical microbiologistQ24550686
Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 proteinQ24561768
Identification of a poxvirus gene encoding a uracil DNA glycosylaseQ24562952
Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNAQ27729896
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNAQ27733802
Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysisQ28298751
Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylaseQ28345101
Mutations in active-site residues of the uracil-DNA glycosylase encoded by vaccinia virus are incompatible with virus viabilityQ28775711
Poxviruses: an emerging portrait of biological strategyQ33502462
Role of vaccinia virus A20R protein in DNA replication: construction and characterization of temperature-sensitive mutantsQ33837263
The A20R protein is a stoichiometric component of the processive form of vaccinia virus DNA polymeraseQ33870353
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.Q33889451
Emergency response to a smallpox attack: the case for mass vaccination.Q34076400
A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutionsQ34290231
Isolation and characterization of the human uracil DNA glycosylase geneQ34318363
Keynote: past, present, and future aspects of base excision repairQ34367323
Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cellsQ34462457
Genome-wide analysis of vaccinia virus protein-protein interactionsQ35700178
Genetically engineered poxviruses for recombinant gene expression, vaccination, and safetyQ37249251
Physical association of the human base-excision repair enzyme uracil DNA glycosylase with the 70,000-dalton catalytic subunit of DNA polymerase alphaQ37402553
Efficient site-directed mutagenesis using uracil-containing DNA.Q37479506
Cytoplasmic transcription system encoded by vaccinia virusQ37626282
Cleavage and binding of a DNA fragment containing a single 8-oxoguanine by wild type and mutant FPG proteinsQ38318188
Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity.Q39611232
Construction of a vaccinia virus deficient in the essential DNA repair enzyme uracil DNA glycosylase by a complementing cell lineQ39880126
A poxvirus-encoded uracil DNA glycosylase is essential for virus viabilityQ40044717
P4510describes a project that usesImageQuantQ112270642
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectVaccinia virusQ1986297
P304page(s)4950-4957
P577publication date2003-08-01
P1433published inNucleic Acids ResearchQ135122
P1476titleCharacterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase
P478volume31

Reverse relations

cites work (P2860)
Q60046531Aberrant repair initiated by the adenine-DNA glycosylase does not play a role in UV-induced mutagenesis in
Q34427857B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil
Q35648649Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase.
Q33310273Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
Q40867415Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA.
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Q21256415Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly
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Q24672089Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms
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Q27664642Vaccinia Virus D4 Mutants Defective in Processive DNA Synthesis Retain Binding to A20 and DNA