Helen Griffiths

British biomedical scientist

Helen Griffiths is …
instance of (P31):
humanQ5

External links are
P8446Gateway to Research person ID0AD784CB-D8FB-499D-B17F-3FF96A6762A1
P856official websitehttps://www.surrey.ac.uk/people/helen-griffiths
P496ORCID iD0000-0002-2666-2147
P3829Publons author ID1181380
P1053ResearcherIDE-3453-2013
P1153Scopus author ID57193264946

P166award receivedFellow of the Royal Society of BiologyQ28020499
Fellow of the Learned Society of WalesQ59772620
P27country of citizenshipUnited KingdomQ145
P69educated atUniversity of BirminghamQ223429
P108employerQueen Elizabeth Hospital BirminghamQ7270344
University of BirminghamQ223429
University of SurreyQ546976
Aston UniversityQ750066
University of LeicesterQ1333399
P734family nameGriffithsQ21508954
GriffithsQ21508954
GriffithsQ21508954
P735given name???Q13376892
???Q13376892
P463member ofLearned Society of WalesQ371160
P106occupationbiomedical scientistQ4915128
university teacherQ1622272
P21sex or genderfemaleQ6581072

Reverse relations

author (P50)
Q720672168-Hydroxydeoxyguanosine. A marker of oxidative DNA damage in systemic lupus erythematosus
Q40059425A comparison of the apoptotic and cytotoxic effects of hexanedione derivatives on human non-neuronal lines and the neuroblastoma line SH-SY5Y.
Q34216141A novel silicon membrane-based biosensing platform using distributive sensing strategy and artificial neural networks for feature analysis.
Q37580915Aberrant reactive oxygen and nitrogen species generation in rheumatoid arthritis (RA): causes and consequences for immune function, cell survival, and therapeutic intervention.
Q85235760Activation of the neutrophil respiratory burst by plasma from periodontitis patients is mediated by pro-inflammatory cytokines
Q33232282Alpha tocopherol supplementation elevates plasma apolipoprotein A1 isoforms in normal healthy subjects
Q34659813An almond-enriched diet increases plasma α-tocopherol and improves vascular function but does not affect oxidative stress markers or lipid levels.
Q34326755An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression.
Q40182343Apoptotic and necrotic effects of hexanedione derivatives on the human neuroblastoma line SK-N-SH.
Q42175264Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells.
Q51673816Are lipid ratios less susceptible to change with systemic inflammation than individual lipid components in patients with rheumatoid arthritis?
Q44615026Ascorbate and α-tocopherol differentially modulate reactive oxygen species generation by neutrophils in response to FcγR and TLR agonists
Q42730196Ascorbic acid in the 21st century - more than a simple antioxidant.
Q62472842Binding of anti-DNA antibodies to oxidatively damaged DNA in spouses and relatives of patients with systemic lupus erythematosus
Q34701833Biomarkers.
Q40334569C-reactive protein mediates CD11b expression in monocytes through the non-receptor tyrosine kinase, Syk, and calcium mobilization but not through cytosolic peroxides
Q55059347CD4(+) T cell surface alpha enolase is lower in older adults.
Q40140133Cell passage-associated transient high oxygenation causes a transient decrease in cellular glutathione and affects T cell responses to apoptotic and mitogenic stimuli
Q41910048Ceramide induces a loss in cytosolic peroxide levels in mononuclear cells
Q57358999Ceramides reduce CD36 cell surface expression and oxidised LDL uptake by monocytes and macrophages
Q62472831Chemiluminescence determination of hydroperoxides following radiolysis and photolysis of free amino acids
Q44274290Deoxycytidine glyoxal: lesion induction and evidence of repair following vitamin C supplementation in vivo.
Q38635822Designing liposomal adjuvants for the next generation of vaccines.
Q46796687Dietary habits are major determinants of the plasma antioxidant status in healthy elderly subjects
Q91518853Dietary protein insufficiency: an important consideration in fatty liver disease?
Q57132532Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells
Q33268962Dose-dependent modulation of the T cell proteome by ascorbic acid
Q45171661Downstream effects on human low density lipoprotein of homocysteine exported from endothelial cells in an in vitro system.
Q44034973Effects of oral vitamin C on monocyte: endothelial cell adhesion in healthy subjects
Q42526611Evidence for sensitisation of DNA to oxidative damage during isolation.
Q48258247Free radical reaction products and antioxidant capacity in beating heart coronary artery surgery compared to conventional bypass
Q42494792Free radicals and redox signalling in T-cells during chronic inflammation and ageing
Q41911510Gingipains from Porphyromonas gingivalis increase the chemotactic and respiratory burst-priming properties of the 77-amino-acid interleukin-8 variant
Q46961720Gravity spun polycaprolactone fibers for applications in vascular tissue engineering: proliferation and function of human vascular endothelial cells
Q42011917Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion.
Q38350451Immunochemical detection of UV-induced DNA damage and repair
Q77919945Immunochemical detection of glyoxal DNA damage
Q42275396Immunochemical detection of sequence-specific modifications to DNA induced by UV light.
Q62472851Immunogenic and antigenic epitopes of immunoglobulin—XX. Denaturation of human IgG3 by free radicals
Q46300558In vivo vitamin C supplementation increases phosphoinositol transfer protein expression in peripheral blood mononuclear cells from healthy individuals
Q38742179Innovative biomarkers for predicting type 2 diabetes mellitus: relevance to dietary management of frailty in older adults.
Q37215816Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?
Q41374680LDL-lipids from patients with hypercholesterolaemia and Alzheimer's disease are inflammatory to microvascular endothelial cells: mitigation by statin intervention
Q37129611Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study.
Q39328053Lipid (per) oxidation in mitochondria: an emerging target in the ageing process?
Q61976278Macular Pigment Optical Density is Related to Blood Glutathione Levels in Healthy Individuals
Q39815258Metabolic memory effect of the saturated fatty acid, palmitate, in monocytes
Q39640723Mitochondrial superoxide anion radicals mediate induction of apoptosis in cardiac myoblasts exposed to chronic hypoxia.
Q47849891Molecular and cellular effects of ultraviolet light-induced genotoxicity
Q34366407Monocytes in coronary artery disease and atherosclerosis: where are we now?
Q28081351Novel ageing-biomarker discovery using data-intensive technologies
Q60585124Novel repair action of vitamin C upon in vivo oxidative DNA damage
Q39143886Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species
Q42730082Oxidation of protein in human low-density lipoprotein exposed to peroxyl radicals facilitates uptake by monocytes; protection by antioxidants in vitro.
Q43157755Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance.
Q51368849Oxidative and inflammatory status in Type 2 diabetes patients with periodontitis.
Q73691359Oxidative modification of a specific apolipoprotein B lysine residue confers altered receptor specificity on LDL
Q54716764Oxidative stress in diabetes - circulating advanced glycation end products, lipid oxidation and vascular disease.
Q69821826Oxygen radical induced alterations in polyclonal IgG
Q47729519Oxygen radical induced fluorescence in proteins; identification of the fluorescent tryptophan metabolite, N-formyl kynurenine, as a biological index of radical damage.
Q54377476Oxygen tension modulates the cytokine response of oral epithelium to periodontal bacteria.
Q39341045Palmitate promotes monocyte atherogenicity via de novo ceramide synthesis.
Q34337682Plasma antioxidant status, immunoglobulin g oxidation and lipid peroxidation in demented patients: relevance to Alzheimer disease and vascular dementia
Q34504921Plasma levels of HDL and carotenoids are lower in dementia patients with vascular comorbidities.
Q67993274Probing molecular changes induced in DNA by reactive oxygen species with monoclonal antibodies
Q34178783Proteomic analysis of a noninvasive human model of acute inflammation and its resolution: the twenty-one day gingivitis model
Q48192514Serum α-Tocopherol Has a Nonlinear Inverse Association with Periodontitis among US Adults.
Q38116654Stabilising cysteinyl thiol oxidation and nitrosation for proteomic analysis.
Q43255462Statin use in rheumatoid arthritis in relation to actual cardiovascular risk: evidence for substantial undertreatment of lipid-associated cardiovascular risk?
Q50755347Studies on the neurotoxicity of 6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline (salsolinol) in SH-SY5Y cells.
Q34795739Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro
Q62472749Terminal galactose residues on transferrin are increased in midlife adults compared to young adults.
Q71215345The C1q binding activity of IgG is modified in vitro by reactive oxygen species: implications for rheumatoid arthritis
Q60585121The Effects of Vitamin C Supplementation on Protein Oxidation in Healthy Volunteers
Q41978298The anti-inflammatory actions of methotrexate are critically dependent upon the production of reactive oxygen species
Q47929276The antioxidant enzyme peroxiredoxin-2 is depleted in lymphocytes seven days after ultra-endurance exercise.
Q52650690The dual role of ROS in autoimmune and inflammatory diseases: Evidence from preclinical models.
Q69334332The effects of oxygen free radicals on the carbohydrate moiety of IgG
Q40475716The presence of ascorbate induces expression of brain derived neurotrophic factor in SH-SY5Y neuroblastoma cells after peroxide insult, which is associated with increased survival.
Q37766875The role of monocytes in atherosclerotic coronary artery disease.
Q62472846The selective protection afforded by ebselen against lipid peroxidation in an ROS-dependent model of inflammation
Q37350028The use of proteomic techniques to explore the holistic effects of nutrients in vivo
Q35614227Thiol redox homeostasis in neurodegenerative disease
Q34934874Urinary 8-oxo-2'-deoxyguanosine: redox regulation of DNA repair in vivo?
Q44555297Validation of a novel ELISA for measurement of MDA-LDL in human plasma.
Q55067476Vitamin C exhibits pro-oxidant properties.
Q44539001Vitamin C supplementation in normal subjects reduces constitutive ICAM-1 expression.

Q48825881Continual learning. Interview by Helen Griffiths.main subjectP921

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