Empagliflozin (BI 10773), a Potent and Selective SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects

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Empagliflozin (BI 10773), a Potent and Selective SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CPDD.16
P698PubMed publication ID27121669

P50authorGerhard NehmizQ56462163
P2093author name stringHans J Woerle
Leo Seman
Sreeraj Macha
Bailuo Ren
Gudrun Simons
Klaus Dugi
Sabine Pinnetti
P2860cites workCorrection of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic ratsQ24563606
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SGLT2 inhibition--a novel strategy for diabetes treatmentQ34117872
Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implicationsQ34120717
Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitorsQ34222752
Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetesQ34227891
Adherence to preventive medications: predictors and outcomes in the Diabetes Prevention ProgramQ35568881
Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetesQ37139427
Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target.Q37645623
Current issues in the treatment of type 2 diabetes. Overview of newer agents: where treatment is goingQ37703703
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Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats.Q41015653
Learning from glycosuriaQ42641850
Renal compensation for impaired hepatic glucose release during hypoglycemia in type 2 diabetes: further evidence for hepatorenal reciprocityQ44452992
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Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjectsQ46171594
Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetesQ46818617
Effect of aging on glucose homeostasis: accelerated deterioration of beta-cell function in individuals with impaired glucose toleranceQ46847394
Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999-2002: the National Health and Nutrition Examination SurveyQ46966712
Long-term treatment with empagliflozin, a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.Q51366978
Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)Q57412648
Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjectsQ83764954
Effect of Ipragliflozin (ASP1941), a novel selective sodium-dependent glucose co-transporter 2 inhibitor, on urinary glucose excretion in healthy subjectsQ84856868
Effect of non-persistent use of oral glucose-lowering drugs on HbA1c goal attainmentQ94706800
P433issue2
P304page(s)152-161
P577publication date2013-03-27
P1433published inClinical pharmacology in drug developmentQ27726600
P1476titleEmpagliflozin (BI 10773), a Potent and Selective SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects
P478volume2

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