scholarly article | Q13442814 |
P2093 | author name string | Richard J Auchus | |
Dario Mizrachi | |||
Daniel P Sherbet | |||
Oleg L Guryev | |||
Mahboubeh Papari-Zareei | |||
Siayareh Rambally | |||
Sharareh Akbar | |||
P2860 | cites work | Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity | Q24321936 |
Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase fromStreptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes | Q27653597 | ||
Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 å resolution | Q27729862 | ||
Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily | Q27731273 | ||
Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2 | Q28213668 | ||
The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology | Q28303450 | ||
Glucose-6-phosphate dehydrogenase activity and NADPH/NADP+ ratio in liver and pancreas are dependent on the severity of hyperglycemia in rat | Q28583459 | ||
Characteristics of human types 1, 2 and 3 17 beta-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition | Q28646522 | ||
Oxidized redox state of glutathione in the endoplasmic reticulum | Q29619789 | ||
Short-chain dehydrogenases/reductases (SDR) | Q29620095 | ||
A mutation in the cofactor-binding domain of 11beta-hydroxysteroid dehydrogenase type 2 associated with mineralocorticoid hypertension. | Q32132284 | ||
Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum | Q33937712 | ||
Regulation of corepressor function by nuclear NADH. | Q33957424 | ||
Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer | Q34454994 | ||
Characterization of cDNAs for human estradiol 17 beta-dehydrogenase and assignment of the gene to chromosome 17: evidence of two mRNA species with distinct 5'-termini in human placenta | Q34543730 | ||
Complete amino acid sequence of human placental 17 beta-hydroxysteroid dehydrogenase deduced from cDNA. | Q34556123 | ||
Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor | Q35234301 | ||
Minireview: cellular redox state regulates hydroxysteroid dehydrogenase activity and intracellular hormone potency | Q36073383 | ||
Cofactors, redox state, and directional preferences of hydroxysteroid dehydrogenases | Q36707957 | ||
Basic concepts and recent developments in human steroid hormone biosynthesis | Q36966758 | ||
Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD(P)H responses in pancreatic islet beta cells | Q36966837 | ||
CYP17 Mutation E305G Causes Isolated 17,20-Lyase Deficiency by Selectively Altering Substrate Binding | Q38350188 | ||
Metabolic and morphological differences between rapidly proliferating cancerous and normal breast epithelial cells | Q40007880 | ||
17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer. | Q40027067 | ||
Human 17beta-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells | Q40529567 | ||
Rational proteomics II: electrostatic nature of cofactor preference in the short-chain oxidoreductase (SCOR) enzyme family | Q41891997 | ||
Human 17 beta-hydroxysteroid dehydrogenase: overproduction using a baculovirus expression system and characterization. | Q42067952 | ||
Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome | Q42497234 | ||
The levels of nicotinamide nucleotides in liver microsomes and their possible significance to the function of hexose phosphate dehydrogenase | Q42856341 | ||
Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme | Q43781525 | ||
Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells | Q43821602 | ||
Glutamate-115 renders specificity of human 11beta-hydroxysteroid dehydrogenase type 2 for the cofactor NAD+. | Q44410593 | ||
Rational proteomics I. Fingerprint identification and cofactor specificity in the short-chain oxidoreductase (SCOR) enzyme family. | Q44667171 | ||
Dissection of the physiological interconversion of 5alpha-DHT and 3alpha-diol by rat 3alpha-HSD via transient kinetics shows that the chemical step is rate-determining: effect of mutating cofactor and substrate-binding pocket residues on catalysis | Q45067218 | ||
Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction | Q46734729 | ||
Arginine 276 controls the directional preference of AKR1C9 (rat liver 3alpha-hydroxysteroid dehydrogenase) in human embryonic kidney 293 cells | Q46853033 | ||
Adaptation of energy metabolism in breast cancer brain metastases | Q48269541 | ||
Mechanism-based inactivation of 17 beta,20 alpha-hydroxysteroid dehydrogenase by an acetylenic secoestradiol | Q68748455 | ||
Isolation and sequencing of a complementary deoxyribonucleic acid clone encoding human placental 17 beta-estradiol dehydrogenase: identification of the putative cofactor binding site | Q69413747 | ||
The arginine 276 anchor for NADP(H) dictates fluorescence kinetic transients in 3 alpha-hydroxysteroid dehydrogenase, a representative aldo-keto reductase | Q77937499 | ||
Elucidation of a complete kinetic mechanism for a mammalian hydroxysteroid dehydrogenase (HSD) and identification of all enzyme forms on the reaction coordinate: the example of rat liver 3alpha-HSD (AKR1C9) | Q81234512 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | hydroxysteroid | Q2157080 |
P304 | page(s) | 4154-4162 | |
P577 | publication date | 2009-06-25 | |
P1433 | published in | Endocrinology | Q3054009 |
P1476 | title | Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells | |
P478 | volume | 150 |
Q50533271 | A validated and rapid high-performance liquid chromatography method for the quantification of conversion of radio-labelled sex steroids. |
Q64226471 | Effect of Oxidative Stress on the Estrogen-NOS-NO-K Channel Pathway in Uteroplacental Dysfunction: Its Implication in Pregnancy Complications |
Q27322084 | Insights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigation |
Q24613957 | The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders |
Q34130698 | The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells |
Q27009283 | The structural biology of oestrogen metabolism |
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