Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome

scientific article

Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2337/DIAB.38.9.1165
P698PubMed publication ID2670645

P2093author name stringDunaif A
Futterweit W
Dobrjansky A
Segal KR
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
polycystic ovary syndromeQ500816
insulin resistanceQ1053470
polycystic ovaryQ5547896
preproinsulinQ7240673
P304page(s)1165-1174
P577publication date1989-09-01
P1433published inDiabetesQ895262
P1476titleProfound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
P478volume38

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cites work (P2860)
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Q37608349Obesity management in women with polycystic ovary syndrome.
Q43918197Obesity, rather than menstrual cycle pattern or follicle cohort size, determines hyperinsulinaemia, dyslipidaemia and hypertension in ageing women with polycystic ovary syndrome
Q34536081Obstructive sleep apnea and metabolic dysfunction in polycystic ovary syndrome
Q39391344Obstructive sleep apnoea and polycystic ovary syndrome: A comprehensive review of clinical interactions and underlying pathophysiology
Q34301379On the association between valproate and polycystic ovary syndrome
Q34693587Oocyte maturation: the coming of age of a germ cell
Q43274978Optimal waist circumference for prediction of metabolic syndrome in young Korean women with polycystic ovary syndrome.
Q40212931Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial
Q57458409Ovarian and Extra-Ovarian Mediators in the Development of Polycystic Ovary Syndrome
Q46916845Ovarian dysfunction in peripubertal hyperinsulinemia
Q33742664Ovarian morphology is associated with insulin resistance in women with polycystic ovary syndrome: a cross sectional study
Q34696198Ovarian steroids: the good, the bad, and the signals that raise them
Q46191480Ovarian stimulation in obese and non-obese polycystic ovary syndrome using a low-dose step-up regimen with two different starting doses of recombinant follicle-stimulating hormone
Q83974732Oxidative status and its relation with insulin resistance in young non-obese women with polycystic ovary syndrome
Q36508886PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity
Q38861206PHYSIOLOGY AND ENDOCRINOLOGY SYMPOSIUM: Insulin action and lipotoxicity in the development of polycystic ovary syndrome: A review
Q30359255Pancreatic β-cell dysfunction in polycystic ovary syndrome: role of hyperglycemia-induced nuclear factor-κB activation and systemic inflammation.
Q37044215Pancreatic β-cell dysfunction in polycystic ovary syndrome: the role of metformin
Q30371644Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome.
Q46051147Participation of ERalpha and ERbeta in glucose homeostasis in skeletal muscle and white adipose tissue
Q26738511Pathophysiology, risk factors, and screening methods for prediabetes in women with polycystic ovary syndrome
Q36943172Patterns of LHbetacf among women in health and disease
Q35572930Peripheral insulin resistance in obese girls with hyperandrogenism is related to oxidative phosphorylation and elevated serum free fatty acids
Q34442683Pharmacological treatment of obesity in patients with polycystic ovary syndrome
Q34024181Phosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states
Q37250408Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys
Q46470138Plasma cytokines in obese women with polycystic ovary syndrome, before and after metformin treatment
Q36666354Polycystic Ovary Syndrome and Obstructive Sleep Apnea
Q35075035Polycystic Ovary Syndrome in the Pediatric Population
Q27021307Polycystic Ovary Syndrome: Important Underrecognised Cardiometabolic Risk Factor in Reproductive-Age Women
Q33775146Polycystic Ovary Syndrome: Insights into the Therapeutic Approach with Inositols
Q92437260Polycystic Ovary Syndrome: Pathophysiology, Presentation, and Treatment With Emphasis on Adolescent Girls
Q43728725Polycystic ovarian syndrome (PCOS) and insulin resistance
Q34345051Polycystic ovarian syndrome in women with epilepsy: a review
Q50859636Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian women.
Q79148960Polycystic ovary syndrome
Q80844876Polycystic ovary syndrome
Q83062366Polycystic ovary syndrome
Q88098767Polycystic ovary syndrome
Q37990356Polycystic ovary syndrome and chronic inflammation: pharmacotherapeutic implications
Q77694096Polycystic ovary syndrome and insulin resistance: thrifty genes struggling with over-feeding and sedentary life style?
Q38380065Polycystic ovary syndrome and insulin: our understanding in the past, present and future
Q33655236Polycystic ovary syndrome and risk of endometrial, ovarian, and breast cancer: a systematic review
Q39455340Polycystic ovary syndrome and the risk of obstructive sleep apnea: a meta-analysis and review of the literature
Q36622133Polycystic ovary syndrome in adolescents: current and future treatment options
Q36182504Polycystic ovary syndrome is a risk factor for type 2 diabetes: results from a long-term prospective study
Q36920069Polycystic ovary syndrome is not associated with genetic variants that mark risk of type 2 diabetes
Q40621362Polycystic ovary syndrome--long-term metabolic consequences
Q39334166Polycystic ovary syndrome: Understanding the role of the brain.
Q38218598Polycystic ovary syndrome: a common hormonal condition with major metabolic sequelae that physicians should know about
Q21245262Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan
Q34100589Polycystic ovary syndrome: an endocrine and metabolic disease
Q41628765Polycystic ovary syndrome: cardiovascular risk factors according to specific phenotypes
Q36554676Polycystic ovary syndrome: clinical presentation in normal-weight compared with overweight adolescents
Q40831696Polycystic ovary syndrome: current and future treatment paradigms
Q37832125Polycystic ovary syndrome: etiology, pathogenesis and diagnosis
Q40942933Polycystic ovary syndrome: pathophysiology and outcome with in vitro fertilization.
Q43621921Polycystic ovary syndrome: relationship between insulin sensitivity, sex hormone levels and ovarian stromal blood flow
Q77690927Polycystic ovary syndrome: symptomatology, pathophysiology, and epidemiology
Q34758467Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome
Q35896531Potential use of durian fruit (Durio zibenthinus Linn) as an adjunct to treat infertility in polycystic ovarian syndrome
Q36732197Predictors of insulin resistance and metabolic complications in polycystic ovarian syndrome in an eastern Indian population
Q36862243Pregnancy in polycystic ovary syndrome
Q36050627Preliminary evidence of glycogen synthase kinase 3 beta as a genetic determinant of polycystic ovary syndrome
Q77694072Premature pubarche, ovarian hyperandrogenism, hyperinsulinism and the polycystic ovary syndrome: from a complex constellation to a simple sequence of prenatal onset
Q37001625Prenatal androgen excess negatively impacts body fat distribution in a nonhuman primate model of polycystic ovary syndrome
Q40836292Prevalence and possible mechanisms of reactive hypoglycemia in polycystic ovary syndrome.
Q38465193Prevalence of elevated glycated hemoglobin in women with polycystic ovary syndrome
Q37019757Prevalence of hepatic steatosis in women with polycystic ovary syndrome
Q51747364Prevalence of psychiatric disorders in patients with polycystic ovary syndrome
Q46826968Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in first-degree relatives of subjects with polycystic ovary syndrome.
Q54596205Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome.
Q93173211Proteomics analysis of potential serum biomarkers for insulin resistance in patients with polycystic ovary syndrome
Q48086732Psychiatric comorbidity in women with polycystic ovary syndrome
Q35489785Puberty and polycystic ovarian syndrome: the insulin/insulin-like growth factor I hypothesis.
Q35906966Recent advances in the treatment of polycystic ovary syndrome
Q45282731Recombinant human insulin-like growth factor I (rhIGF I) reduces hyperglycaemia in patients with extreme insulin resistance
Q38864973Relationship among plasma adipokines, insulin and androgens level as well as biochemical glycemic and lipidemic markers with incidence of PCOS in women with normal BMI.
Q78966636Relationship between polycystic ovaries, body mass index and insulin resistance
Q45168757Relationship between the triglyceride/high-density lipoprotein-cholesterol ratio, insulin resistance index and cardiometabolic risk factors in women with polycystic ovary syndrome
Q44473918Relative impact of insulin resistance and obesity on cardiovascular risk factors in polycystic ovary syndrome
Q26828765Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome
Q46979381Risk of T2DM and impaired fasting glucose among PCOS subjects: results of an 8-year follow-up
Q35798745Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women
Q33591300Risk of psychiatric disorders following polycystic ovary syndrome: a nationwide population-based cohort study
Q26774060Role of Anti-Müllerian Hormone in pathophysiology, diagnosis and treatment of Polycystic Ovary Syndrome: a review
Q54440177Role of GnRH drive in the pathophysiology of polycystic ovary syndrome.
Q37355743Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity
Q88991120Role of osteocalcin, tumor necrosis factor-alpha and adiponectin in polycystic ovary syndrome patients with insulin resistance
Q37360333Saturated fatty acid exposure induces androgen overproduction in bovine adrenal cells
Q28390200Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome
Q28360761Screening for diabetes in pregnancy
Q37097161Searching for polycystic ovary syndrome in postmenopausal women: evidence of a dose-effect association with prevalent cardiovascular disease
Q51590281Sensitivity of plasma insulin levels in obese and non-obese women with functional hyperandrogenism.
Q37445314Serum C-reactive protein levels in normal-weight polycystic ovary syndrome
Q43491849Serum Fetuin-A levels, insulin resistance and oxidative stress in women with polycystic ovary syndrome
Q51312640Serum HLA-G levels in women with polycystic ovary syndrome.
Q46525200Serum and follicular fluid levels of soluble Fas, soluble Fas ligand and apoptosis of luteinized granulosa cells in PCOS patients undergoing IVF.
Q50654959Serum anti-Müllerian hormone and insulin resistance in the main phenotypes of non-obese polycystic ovarian syndrome women in China.
Q33814094Serum concentrations of afamin are elevated in patients with polycystic ovary syndrome
Q46544840Serum free fatty acid levels in PCOS patients treated with glucophage, magnesium oxide and spironolactone
Q84328513Serum lipocalin-2 as an insulin resistance marker in patients with polycystic ovary syndrome
Q51361441Serum visfatin levels in women with polycystic ovary syndrome.
Q37618529Sex differences in the effects of androgens acting in the central nervous system on metabolism
Q40418781Sex differences, endogenous sex-hormone hormones, sex-hormone binding globulin, and exogenous disruptors in diabetes and related metabolic outcomes
Q36931218Sex hormone-binding globulin genetic variation: associations with type 2 diabetes mellitus and polycystic ovary syndrome.
Q30423117Should all women with PCOS be treated for insulin resistance?
Q33516103Simple modeling allows prediction of steady-state glucose disposal rate from early data in hyperinsulinemic glucose clamps.
Q28917062Sleep Duration, Exercise, Shift Work and Polycystic Ovarian Syndrome-Related Outcomes in a Healthy Population: A Cross-Sectional Study
Q36217225Spironolactone for hirsutism in polycystic ovary syndrome
Q46426588Spironolactone in the treatment of polycystic ovary syndrome: effects on clinical features, insulin sensitivity and lipid profile.
Q35233754State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS).
Q38221447Steroidogenesis-adrenal cell signal transduction
Q35688517Suitability of recommended limits for fasting glucose tests in women with polycystic ovary syndrome
Q83170982Surgical treatment of obesity
Q51372667Symmetric dimethylarginine (SDMA) is raised in women with polycystic ovary syndrome: a pilot study.
Q35754543Systems Genetics Reveals the Functional Context of PCOS Loci and Identifies Genetic and Molecular Mechanisms of Disease Heterogeneity
Q38809734Testosterone therapy for transgender men.
Q35786489The Effect of Exercise in PCOS Women Who Exercise Regularly
Q35676497The Genetic Basis of the Polycystic Ovary Syndrome: A Literature Review Including Discussion of PPAR-gamma.
Q38597944The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Q41640666The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited
Q36719299The adipose cell lineage is not intrinsically insulin resistant in polycystic ovary syndrome
Q34190360The comparison of insulin resistance frequency in patients with recurrent early pregnancy loss to normal individuals
Q39401759The contribution of diet, physical activity and sedentary behaviour to body mass index in women with and without polycystic ovary syndrome.
Q41690430The effect of metformin use on pregnancy rates among polycystic ovary syndrome patients undergoing in vitro fertilization: A retrospective-cohort study
Q64111152The effectiveness of high intensity intermittent training on metabolic, reproductive and mental health in women with polycystic ovary syndrome: study protocol for the iHIT- randomised controlled trial
Q42476947The effects of metformin on insulin resistance and ovarian steroidogenesis in women with polycystic ovary syndrome
Q35181929The effects of metformin or orlistat on obese women with polycystic ovary syndrome: a prospective randomized open-label study
Q36328060The effects of old, new and emerging medicines on metabolic aberrations in PCOS.
Q46948248The effects of rosiglitazone and metformin on insulin resistance and serum androgen levels in obese and lean patients with polycystic ovary syndrome
Q46669792The effects of rosiglitazone and metformin on oxidative stress and homocysteine levels in lean patients with polycystic ovary syndrome
Q37238230The efficacy of metformin and clomiphene citrate combination compared with clomiphene citrate alone for ovulation induction in infertile patients with PCOS
Q50204098The impact of androgen actions in neurons on metabolic health and disease
Q45277759The impact of insulin resistance on the outcome of laparoscopic ovarian electrocautery in infertile women with the polycystic ovary syndrome
Q36971967The impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women in two randomized, placebo-controlled clinical trials
Q51752247The impact of oral contraceptives and metformin on anti-Müllerian hormone serum levels in women with polycystic ovary syndrome and biochemical hyperandrogenemia
Q34026359The in utero programming effect of increased maternal androgens and a direct fetal intervention on liver and metabolic function in adult sheep
Q40389350The link between insulin resistance and hypertension. Effects of antihypertensive and antihyperlipidaemic drugs on insulin sensitivity
Q24798425The management of infertility associated with polycystic ovary syndrome
Q28248914The menstrual cycle regularization following D-chiro-inositol treatment in PCOS women: a retrospective study
Q41952999The metabolic syndrome in children and adolescents
Q30440354The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome
Q77694083The pathogenesis of polycystic ovary syndrome: lessons from ovarian stimulation studies
Q64907714The phenotypes of polycystic ovary syndrome defined by the 1990 diagnostic criteria are associated with higher serum vaspin levels than the phenotypes introduced by the 2003 criteria.
Q34163132The polycystic ovary syndrome: treatment with insulin sensitizing agents
Q34997987The prevalence and risk factors for glucose intolerance in young Korean women with polycystic ovary syndrome
Q51486636The prevalence of polycystic ovaries in Chinese women with a history of gestational diabetes mellitus.
Q38231822The rationale of the myo-inositol and D-chiro-inositol combined treatment for polycystic ovary syndrome
Q44016360The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue.
Q46191484The relationship between clinico-biochemical characteristics and psychiatric distress in young women with polycystic ovary syndrome
Q36259103The relationship between epicardial fat tissue thickness and visceral adipose tissue in lean patients with polycystic ovary syndrome
Q40196769The relationship between metabolic status and levels of adiponectin and ghrelin in lean women with polycystic ovary syndrome
Q90177690The role of a pulse-based diet on infertility measures and metabolic syndrome risk: protocol of a randomized clinical trial in women with polycystic ovary syndrome
Q42488875The role of insulin in ovarian size in patients with the polycystic ovary syndrome
Q34998688The use of metformin in the management of polycystic ovary syndrome and associated anovulatory infertility: the current evidence
Q36799800Therapeutic options in the polycystic ovary syndrome
Q46104097Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome
Q43725577Tissue insulin sensitivity and body weight in polycystic ovary syndrome
Q36098781To Assess the Association between Glucose Metabolism and Ectopic Lipid Content in Different Clinical Classifications of PCOS.
Q33399651Transcriptional profiling with a pathway-oriented analysis identifies dysregulated molecular phenotypes in the endometrium of patients with polycystic ovary syndrome
Q42474617Treatment effect of sibutramine compared to fluoxetine on leptin levels in polycystic ovary disease
Q35649437Treatment of PCOS with metformin and other insulin-sensitizing agents
Q34622523Treatment of obstructive sleep apnea improves cardiometabolic function in young obese women with polycystic ovary syndrome
Q37764078Type 2 diabetes and cardiovascular disease in polycystic ovary syndrome: what are the risks and can they be reduced?
Q42983706Umbilical vein testosterone in female infants born to mothers with polycystic ovary syndrome is elevated to male levels
Q77690932Understanding the underlying metabolic abnormalities of polycystic ovary syndrome and their implications
Q51492093Use of metformin for ovulation induction in women who have polycystic ovary syndrome with or without evidence of insulin resistance.
Q37769526Use of metformin in the treatment of polycystic ovary syndrome
Q53761370Visceral adiposity index levels in overweight and/or obese, and non-obese patients with polycystic ovary syndrome and its relationship with metabolic and inflammatory parameters.
Q60047409Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): A cross-sectional study
Q38072104Vitamin D in human reproduction: a narrative review
Q50880365Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp.
Q35225508World Congress on Insulin Resistance, Diabetes, and Cardiovascular Disease: part 4.
Q46142884World Congress on the Insulin Resistance Syndrome, 2009: Insulin resistance mechanisms, the brain, and insulin resistance in youth and in the polycystic ovary syndrome
Q89736882Wrist circumference: A new marker for insulin resistance in African women with polycystic ovary syndrome
Q51481042[Insulin resistance and metabolic profile in lean and overweight/obese polycystic ovary syndrome patients].
Q79566798[Polycystic ovary syndrome. Prototype of a cardio-metabolic syndrome]

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