Hyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus

scientific article published on January 1995

Hyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0002-9343(99)80057-6
P698PubMed publication ID7825639

P2093author name stringA Dunaif
P2860cites workSignal transduction by receptors with tyrosine kinase activityQ27860624
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction proteinQ28116980
The function of GRB2 in linking the insulin receptor to Ras signaling pathwaysQ28259867
Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexesQ30194979
Mapping Diabetes-Susceptibility Genes: Lessons Learned From Search for DNA Marker for Maturity-Onset Diabetes of the YoungQ36216103
Interplay between insulin signalling and protein kinase C.Q37300882
Insulin resistance with acanthosis nigricans: the roles of obesity and androgen excessQ38351252
The insulin receptor and its substrate: molecular determinants of early events in insulin action.Q40485215
Hyperinsulinemia is associated with menstrual irregularity and altered serum androgens in Pima Indian women.Q40669866
Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: candidates for a signal transmitter defect causing insulin resistance of the skeletal muscleQ40852707
The new elements of insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domainsQ40853423
Opposing actions of dehydroepiandrosterone and testosterone on insulin sensitivity. In vivo and in vitro studies of hyperandrogenic femalesQ41152334
Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndromeQ42497234
Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperinsulinemiaQ42517167
Evidence for insulin resistance in nonobese patients with polycystic ovarian diseaseQ44534969
Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in U.S. population aged 20-74 yr.Q44788399
The relationship of insulin insensitivity to menstrual pattern in women with hyperandrogenism and polycystic ovaries.Q51599304
Acanthosis Nigricans, insulin action, and hyperandrogenism: clinical, histological, and biochemical findings.Q51609532
Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.Q51613168
Acanthosis nigricans in obese women with hyperandrogenism. Characterization of an insulin-resistant state distinct from the type A and B syndromes.Q51639294
Absence of insulin receptor gene mutations in three insulin-resistant women with the polycystic ovary syndrome.Q53814172
Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndromeQ67555170
Insulin action in non-insulin-dependent diabetes mellitus: the relationship between hepatic and extrahepatic insulin resistance and obesityQ68197320
Diabetes in identical twins. A study of 200 pairsQ70659026
Evidence for the Importance of Peripheral Tissue Events in the Development of Hirsutism in Polycystic Ovary Syndrome*Q72788023
Evidence for a single gene effect causing polycystic ovaries and male pattern baldnessQ72839906
P433issue1A
P407language of work or nameEnglishQ1860
P921main subjectpreproinsulinQ7240673
P304page(s)33S-39S
P577publication date1995-01-01
P1433published inAmerican Journal of MedicineQ2842959
P1476titleHyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus
P478volume98

Reverse relations

cites work (P2860)
Q35992640A paradigm for finding genes for a complex human trait: polycystic ovary syndrome and follistatin
Q37214728Adolescents with Classical Polycystic Ovary Syndrome Have Alterations in the Surrogate Markers of Cardiovascular Disease but Not in the Endothelial Function. The Possible Benefits of Metformin.
Q41550093Amenorrhoea
Q34648316Androgen biosynthesis from cholesterol to DHEA.
Q37383118Androgens stimulate early stages of follicular growth in the primate ovary
Q43156471Angiotensin converting enzyme gene insertion/deletion polymorphism in patients with polycystic ovary syndrome
Q42446085Assessment of cardiovascular autonomic function in patients with polycystic ovary syndrome
Q37133808Association of obesity and overweight with the prevalence of insulin resistance, pre-diabetes and clinical-biochemical characteristics among infertile Mexican women with polycystic ovary syndrome: a cross-sectional study
Q42459575Association of sympathovagal imbalance with cardiovascular risks in patients with polycystic ovary syndrome
Q57414617Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians
Q51581819Can metformin reduce insulin resistance in polycystic ovary syndrome?
Q36013142Cardiometabolic aspects of polycystic ovarian syndrome.
Q39593191Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study
Q34212172Cardiovascular risk in women with polycystic ovary syndrome.
Q44118719Clinical manifestations and insulin resistance (IR) in polycystic ovary syndrome (PCOS) among South Asians and Caucasians: is there a difference?
Q36263860Correlation between serum lipid profile and carotid intima-media thickness in Polycystic Ovarian Syndrome
Q44689102Do polycystic-appearing ovaries affect the risk of cardiovascular disease among women with polycystic ovary syndrome?
Q44104324Early steps in androgen biosynthesis: from cholesterol to DHEA.
Q45217868Effect of rosiglitazone on endocrine, metabolism and ovulatory performance in patients with polycystic ovary syndrome and insulin resistance
Q51565210Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome.
Q46869085Effects of Chinese green tea on weight, and hormonal and biochemical profiles in obese patients with polycystic ovary syndrome--a randomized placebo-controlled trial.
Q28078717Effects of hyperandrogenism on metabolic abnormalities in patients with polycystic ovary syndrome: a meta-analysis
Q94463910Effects of low-dose metformin in Japanese women with clomiphene-resistant polycystic ovary syndrome
Q92325270Evolutionary origins of polycystic ovary syndrome: An environmental mismatch disorder
Q34013754Gender differences in insulin resistance, body composition, and energy balance
Q33559796Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
Q79238454Heart rate variability in young women with polycystic ovary syndrome
Q28144779Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma
Q51837879IgG, IgA and IgM antibodies against FSH: serological markers of pathogenic autoimmunity or of normal immunoregulation?
Q36739203Indices of low-grade inflammation in polycystic ovary syndrome
Q34480793Insulin resistance and fertility in polycystic ovary syndrome
Q81065477Insulin resistance, premature adrenarche, and a risk of the Polycystic Ovary Syndrome (PCOS)
Q46529410Insulin responses to the oral glucose tolerance test in women of different ethnicity with polycystic ovary syndrome
Q35564923Insulin-Lowering Agents in the Management of Polycystic Ovary Syndrome
Q36812747Is there an independent effect of polycystic ovary syndrome (PCOS) and menopause on the prevalence of subclinical atherosclerosis in middle aged women?
Q46135692Lack of insulin resistance in fibroblasts from subjects with polycystic ovary syndrome
Q43586000Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters
Q35228206Long menstrual cycle is associated with type 2 diabetes mellitus in korean women
Q34011105Long-term effect of metformin on metabolic parameters in the polycystic ovary syndrome.
Q38937689Metabolic syndrome in Greek women with polycystic ovary syndrome: prevalence, characteristics and associations with body mass index. A prospective controlled study
Q51737343Metformin improves ovarian follicle dynamics by reducing theca cell proliferation and CYP-17 expression in an androgenized rat model.
Q77656494Molecular medicine of steroid hormone biosynthesis
Q41227904Nutrition, hormones, and breast cancer: is insulin the missing link?
Q42458796Parametrial adipose tissue and metabolic dysfunctions induced by fructose-rich diet in normal and neonatal-androgenized adult female rats
Q41455260Pathophysiology, genetics, and treatment of hyperandrogenism
Q26752564Poly Cystic Ovarian Syndrome: An Updated Overview
Q34345051Polycystic ovarian syndrome in women with epilepsy: a review
Q74044133Polycystic ovary syndrome
Q77919875Polycystic ovary syndrome
Q35692892Polycystic ovary syndrome: a review for primary providers
Q36872445Recent progress in the use of genetics to understand links between type 2 diabetes and related metabolic traits
Q40867121Relationship between hyperandrogenism, obesity, inflammation and polycystic ovary syndrome.
Q43723378Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome.
Q46180967Reproductive history and risk of type 2 diabetes mellitus in postmenopausal women: findings from the Women's Health Initiative
Q27693908Review on autoimmune reactions in female infertility: antibodies to follicle stimulating hormone
Q50877420Role of phyto-oestrogens in ovulation induction in women with polycystic ovarian syndrome.
Q28284145Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome
Q46347674Serum leptin as an additional possible pathogenic factor in polycystic ovary syndrome
Q26999869Sex dimorphism and depot differences in adipose tissue function
Q36533814Symptoms and treatments of polycystic ovary syndrome
Q35608887The pathophysiology of polycystic ovary syndrome
Q34163132The polycystic ovary syndrome: treatment with insulin sensitizing agents
Q51553418The prevalence of polycystic ovaries in women with a history of gestational diabetes.
Q77690932Understanding the underlying metabolic abnormalities of polycystic ovary syndrome and their implications
Q53862512[Micropolycystic ovaries and insulin-resistance syndrome].

Search more.