Antimicrobial peptide-induced apoptotic death of leishmania results from calcium-de pend ent, caspase-independent mitochondrial toxicity

scientific article published on 8 April 2009

Antimicrobial peptide-induced apoptotic death of leishmania results from calcium-de pend ent, caspase-independent mitochondrial toxicity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M809079200
P932PMC publication ID2708846
P698PubMed publication ID19357081

P50authorWojciech KamyszQ16615931
Bradford S McGwireQ125293061
P2093author name stringW Robert McMaster
Manjusha M Kulkarni
P2860cites workThe mechanism of inhibition of mitochondrial oxidative phosphorylation by the non-steroidal anti-inflammatory agent diflunisalQ46867398
The major surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing.Q52574669
Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor.Q52594360
Action of the nonsteroidal anti-inflammatory agent, flufenamic acid, on calcium movements in isolated mitochondriaQ68307986
The recruitment of Fas-associated death domain/caspase-8 in Ras-induced apoptosisQ74120231
Flufenamic acid as an inducer of mitochondrial permeability transitionQ74284774
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-betaQ22011091
The genome of the kinetoplastid parasite, Leishmania majorQ22065797
In vitro antibacterial properties of pexiganan, an analog of magaininQ28343235
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosisQ28588618
Protegrins: new antibiotics of mammalian originQ34074990
Nitric oxide-mediated proteasome-dependent oligonucleosomal DNA fragmentation in Leishmania amazonensis amastigotesQ34125669
Crystallization of antimicrobial pores in membranes: magainin and protegrinQ34174099
Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculumQ35025132
Calcium regulation in protozoan parasitesQ35206897
Apoptosis driven infection.Q36827955
A modified colorimetric assay of macrophage activation for intracellular cytotoxicity against Leishmania parasitesQ39135299
N-terminal fatty acid substitution increases the leishmanicidal activity of CA(1-7)M(2-9), a cecropin-melittin hybrid peptideQ39478158
Single and combination toxic metal exposures induce apoptosis in cultured murine podocytes exclusively via the extrinsic caspase 8 pathwayQ40327947
Miltefosine induces apoptosis-like death in Leishmania donovani promastigotesQ40622211
The plasma membrane of Leishmania donovani promastigotes is the main target for CA(1-8)M(1-18), a synthetic cecropin A-melittin hybrid peptideQ42125882
Characterization of metacaspases with trypsin-like activity and their putative role in programmed cell death in the protozoan parasite LeishmaniaQ42628343
Hydrogen peroxide induces apoptosis-like death in Leishmania donovani promastigotesQ43739533
On the evolution of programmed cell death: apoptosis of the unicellular eukaryote Leishmania major involves cysteine proteinase activation and mitochondrion permeabilizationQ43861755
Cell death in Leishmania induced by stress and differentiation: programmed cell death or necrosis?Q44137080
Antimonial-induced Increase in Intracellular Ca2+ through Non-selective Cation Channels in the Host and the Parasite Is Responsible for Apoptosis of Intracellular Leishmania donovani AmastigotesQ44411414
Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovaniQ44521855
Killing of African trypanosomes by antimicrobial peptidesQ44806647
Camptothecin-induced imbalance in intracellular cation homeostasis regulates programmed cell death in unicellular hemoflagellate Leishmania donovaniQ45050518
The caspase-independent algorithm of programmed cell death in Leishmania induced by baicalein: the role of LdEndoG, LdFEN-1 and LdTatD as a DNA 'degradesome'.Q46529657
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectantimicrobial peptideQ1201508
apoptotic processQ14599311
P304page(s)15496-15504
P577publication date2009-04-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleAntimicrobial peptide-induced apoptotic death of leishmania results from calcium-de pend ent, caspase-independent mitochondrial toxicity
P478volume284

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cites work (P2860)
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