Identification of GRO1 as a critical determinant for mutant p53 gain of function

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Identification of GRO1 as a critical determinant for mutant p53 gain of function is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M900994200
P932PMC publication ID2673286
P698PubMed publication ID19258312

P2093author name stringXinbin Chen
Wensheng Yan
P2860cites workThe role of CDP in the negative regulation of CXCL1 gene expressionQ24647127
Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type IIQ24681272
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CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancerQ36228506
Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signalingQ36462813
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Differential regulation of CXC ligand 1 transcription in melanoma cell lines by poly(ADP-ribose) polymerase-1.Q37149860
An NF-kappa B-like transcription factor mediates IL-1/TNF-alpha induction of gro in human fibroblastsQ38334326
Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domainQ39575066
Tumor-derived p53 mutants induce NF-kappaB2 gene expressionQ39614332
Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype.Q39979160
Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB.Q40052470
Targeted repression of bone morphogenetic protein 7, a novel target of the p53 family, triggers proliferative defect in p53-deficient breast cancer cellsQ40073640
Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion.Q40203796
Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathwaysQ40291598
Growth-regulated oncogene is pivotal in thrombin-induced angiogenesisQ40291696
A growth-related oncogene/CXC chemokine receptor 2 autocrine loop contributes to cellular proliferation in esophageal cancerQ40304146
HMGI(Y) and Sp1 in addition to NF-kappa B regulate transcription of the MGSA/GRO alpha geneQ40396385
Growth regulated oncogene-alpha expression by murine squamous cell carcinoma promotes tumor growth, metastasis, leukocyte infiltration and angiogenesis by a host CXC receptor-2 dependent mechanismQ40865256
E2F-1 potentiates cell death by blocking antiapoptotic signaling pathwaysQ40908814
Constitutive and cytokine-induced expression of the melanoma growth stimulatory activity/GRO alpha gene requires both NF-kappa B and novel constitutive factorsQ41258049
KSHV-GPCR and CXCR2 transforming capacity and angiogenic responses are mediated through a JAK2-STAT3-dependent pathwayQ42818551
p21B, a variant of p21(Waf1/Cip1), is induced by the p53 familyQ43890977
Role of melanoma growth stimulatory activity (MGSA/gro) on keratinocyte function in wound healingQ46309627
Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expressionQ46709821
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.Q52561781
The chemokine GRO-alpha (CXCL1) confers increased tumorigenicity to glioma cells.Q54652592
Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines.Q54658705
The gain of function of the p53 mutant Asp281Gly is dependent on its ability to form tetramersQ74523161
Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cellsQ79961179
Analysis of protein-DNA binding by streptavidin-agarose pulldownQ80058687
Prostate tumor CXC-chemokine profile correlates with cell adhesion to endothelium and extracellular matrixQ81428298
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)12178-12187
P577publication date2009-03-03
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of GRO1 as a critical determinant for mutant p53 gain of function
P478volume284

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cites work (P2860)
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