Deoxyelephantopin from Elephantopus scaber Inhibits HCT116 Human Colorectal Carcinoma Cell Growth through Apoptosis and Cell Cycle Arrest

scientific article published on 21 March 2016

Deoxyelephantopin from Elephantopus scaber Inhibits HCT116 Human Colorectal Carcinoma Cell Growth through Apoptosis and Cell Cycle Arrest is …
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scholarly articleQ13442814

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P356DOI10.3390/MOLECULES21030385
P932PMC publication ID6274388
P698PubMed publication ID27007366

P50authorKhalijah AwangQ105935311
P2093author name stringHabsah Abdul Kadir
Chim Kei Chan
Gomathi Chan
P2860cites workCaspases: pharmacological manipulation of cell deathQ24536096
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Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activationQ29976892
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Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-kappaB (nf-kappaB) activation and nf-kappaB-regulated gene expressionQ79188384
Sesquiterpene Lactones from Elephantopus scaber.Q105001193
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Cleavage of Poly(ADP-ribose) polymerase measured in situ in individual cells: relationship to DNA fragmentation and cell cycle position during apoptosisQ30837752
Deoxyelephantopin, a novel multifunctional agent, suppresses mammary tumour growth and lung metastasis and doubles survival time in miceQ33690748
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Antineoplastic effects of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber, on lung adenocarcinoma (A549) cells.Q34835810
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Isodeoxyelephantopin from Elephantopus scaber (Didancao) induces cell cycle arrest and caspase-3-mediated apoptosis in breast carcinoma T47D cells and lung carcinoma A549 cellsQ35151377
Apoptosis in cancer: from pathogenesis to treatmentQ35397889
Elephantopus scaber induces apoptosis through ROS-dependent mitochondrial signaling pathway in HCT116 human colorectal carcinoma cellsQ35599345
Cell cycle arrest and induction of apoptosis by cajanin stilbene acid from Cajanus cajan in breast cancer cellsQ35618377
Sesquiterpene lactones isolated from Elephantopus scaber L. inhibits human lymphocyte proliferation and the growth of tumour cell lines and induces apoptosis in vitroQ35829819
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Anti-metastatic effect of deoxyelephantopin from Elephantopus scaber in A549 lung cancer cells in vitroQ38909057
Effects of nemorosone, isolated from the plant Clusia rosea, on the cell cycle and gene expression in MCF-7 BUS breast cancer cell lines.Q38914820
Deoxyelephantopin impairs growth of cervical carcinoma SiHa cells and induces apoptosis by targeting multiple molecular signaling pathwaysQ38953040
Molecular imaging of p53 signal pathway in lung cancer cell cycle arrest induced by cisplatinQ39335629
Deoxyelephantopin from Elephantopus scaber L. induces cell-cycle arrest and apoptosis in the human nasopharyngeal cancer CNE cellsQ39509804
Antiproliferative activities of five Chinese medicinal herbs and active compounds in Elephantopus scaberQ39796992
P53-mediated cell cycle arrest and apoptosis through a caspase-3- independent, but caspase-9-dependent pathway in oridonin-treated MCF-7 human breast cancer cellsQ40116029
Decreased p21 levels are required for efficient restart of DNA synthesis after S phase blockQ40620254
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Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines.Q42518700
Costunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activationQ43267448
Hinokitiol inhibits cell growth through induction of S-phase arrest and apoptosis in human colon cancer cells and suppresses tumor growth in a mouse xenograft experimentQ45331496
The evaluation of hepatoprotective effects of Taiwan folk medicine 'teng-khia-u'.Q47207696
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcell growthQ189159
apoptotic processQ14599311
Elephantopus scaberQ1039719
colorectal carcinomaQ25493920
P304page(s)385
P577publication date2016-03-21
P1433published inMoleculesQ151332
P1476titleDeoxyelephantopin from Elephantopus scaber Inhibits HCT116 Human Colorectal Carcinoma Cell Growth through Apoptosis and Cell Cycle Arrest
P478volume21