Costunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activation

scientific article published in October 2009

Costunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1248/BPB.32.1803
P698PubMed publication ID19801848

P2093author name stringJung-Hye Choi
Kyung-Tae Lee
P2860cites workSuppressed NF-kB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-a induced apoptosis in human cancer cellsQ23921490
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.Q33960826
Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C releaseQ43546386
P433issue10
P921main subjectleukemiaQ29496
P304page(s)1803-1808
P577publication date2009-10-01
P1433published inBiological and Pharmaceutical BulletinQ15754240
P1476titleCostunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activation
P478volume32

Reverse relations

cites work (P2860)
Q38778271Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human Esophageal Cancer Eca-109 Cells
Q37602110Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
Q38778597Costunolide induces G1/S phase arrest and activates mitochondrial-mediated apoptotic pathways in SK-MES 1 human lung squamous carcinoma cells
Q39468735Costunolide induces apoptosis in platinum-resistant human ovarian cancer cells by generating reactive oxygen species
Q48340248Costunolide induces micronuclei formation, chromosomal aberrations, cytostasis, and mitochondrial-mediated apoptosis in Chinese hamster ovary cells
Q92816035Costunolide-A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential
Q52647690Dammarane-type triterpene ginsenoside-Rg18 inhibits human non-small cell lung cancer A549 cell proliferation via G1 phase arrest.
Q39894917Deoxyelephantopin from Elephantopus scaber Inhibits HCT116 Human Colorectal Carcinoma Cell Growth through Apoptosis and Cell Cycle Arrest
Q37235359Development of Anticancer Agents from Plant-Derived Sesquiterpene Lactones
Q54284939Ginsenoside Rh2 induces cell cycle arrest and differentiation in human leukemia cells by upregulating TGF-β expression.
Q39432180Induction of Fas-mediated extrinsic apoptosis, p21WAF1-related G2/M cell cycle arrest and ROS generation by costunolide in estrogen receptor-negative breast cancer cells, MDA-MB-231.
Q64937338Natural Products and Acute Myeloid Leukemia: A Review Highlighting Mechanisms of Action.
Q26996069Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone
Q36243168Sesquiterpene lactone! a promising antioxidant, anticancer and moderate antinociceptive agent from Artemisia macrocephala jacquem
Q38123215Sesquiterpene lactones: adverse health effects and toxicity mechanisms
Q38345954The role of oxidative stress in anticancer activity of sesquiterpene lactones

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