Blockade of angiotensin II attenuates VEGF-mediated blood-retinal barrier breakdown in diabetic retinopathy

scientific article

Blockade of angiotensin II attenuates VEGF-mediated blood-retinal barrier breakdown in diabetic retinopathy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/JCBFM.2008.154
P698PubMed publication ID19107135
P5875ResearchGate publication ID23688803

P2093author name stringJin Hyoung Kim
Kyu-Won Kim
Jeong Hun Kim
Young Suk Yu
Chang Sik Cho
P2860cites workProangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway.Q30665533
How the diabetic eye loses vision.Q30836019
Dual effect of angiotensin-converting enzyme inhibition on angiogenesis in type 1 diabetic mice.Q31125777
Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivationQ31805054
Molecular mechanisms of vascular permeability in diabetic retinopathyQ33887339
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrierQ34206194
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disordersQ34292807
Early cellular and molecular changes induced by diabetes in the retinaQ34338727
Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primateQ34409210
Perindopril: possible use in cancer therapyQ34620597
Retinal angiogenesis is mediated by an interaction between the angiotensin type 2 receptor, VEGF, and angiopoietinQ35791973
The role of clusterin in retinal development and free radical damageQ36172074
Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin-angiotensin systemQ37318301
Captopril inhibits angiogenesis and slows the growth of experimental tumors in ratsQ37358195
Hepatocyte growth factor suppresses vascular endothelial growth factor-induced expression of endothelial ICAM-1 and VCAM-1 by inhibiting the nuclear factor-kappaB pathway.Q40473859
Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.Q44028824
Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathyQ44247079
Pathophysiological consequences of VEGF-induced vascular permeabilityQ46349878
Suppression of ocular inflammation in endotoxin-induced uveitis by blocking the angiotensin II type 1 receptor.Q46618800
Quantitative receptor autoradiographic analysis for angiotensin II receptors in bovine retinal microvessels: quantitation with radioluminographyQ48278726
AKAP12 regulates human blood-retinal barrier formation by downregulation of hypoxia-inducible factor-1alpha.Q53572840
Tissue inhibition of angiotensin-converting enzyme activity stimulates angiogenesis in vivo.Q54092413
Increased serum angiotensin converting enzyme activity in type I insulin-dependent diabetes mellitus: its relation to metabolic control and diabetic complicationsQ72797749
Retinal neovascularization is prevented by blockade of the renin-angiotensin systemQ73295556
Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes. The EUCLID Study Group. EURODIAB Controlled Trial of Lisinopril in Insulin-Dependent Diabetes MellitusQ74058742
Angiotensin II potentiates vascular endothelial growth factor-induced angiogenic activity in retinal microcapillary endothelial cellsQ74405505
Diabetic retinopathyQ75217418
The role of clusterin in in vitro ischemia of human retinal endothelial cellsQ81243004
P433issue3
P304page(s)621-628
P577publication date2008-12-24
P1433published inJournal of Cerebral Blood Flow & MetabolismQ14663525
P1476titleBlockade of angiotensin II attenuates VEGF-mediated blood-retinal barrier breakdown in diabetic retinopathy
P478volume29

Reverse relations

cites work (P2860)
Q97425097Activation of mas restores hyperoxia-induced loss of lung epithelial barrier function through inhibition of apoptosis
Q36990241Adeno-Associated Virus Overexpression of Angiotensin-Converting Enzyme-2 Reverses Diabetic Retinopathy in Type 1 Diabetes in Mice.
Q44948732Administration of sesamol improved blood-brain barrier function in streptozotocin-induced diabetic rats.
Q37564793Advances in the medical treatment of diabetic retinopathy
Q46483060Aliskiren decreases oxidative stress and angiogenic markers in retinal pigment epithelium cells
Q27025635Alternative pathways in the development of diabetic retinopathy: the renin-angiotensin and kallikrein-kinin systems
Q53124062Angiotensin II receptor blocker improves the lowered exercise capacity and impaired mitochondrial function of the skeletal muscle in type 2 diabetic mice.
Q37304677Animal models of diabetic retinopathy: summary and comparison
Q98613393Apigenin and Ethaverine Hydrochloride Enhance Retinal Vascular Barrier In Vitro and In Vivo
Q37801912Current approaches to the management of diabetic retinopathy and diabetic macular oedema
Q45964657Decursin inhibits VEGF-mediated inner blood-retinal barrier breakdown by suppression of VEGFR-2 activation.
Q49724247Diabetic Retinopathy in the Spontaneously Diabetic Torii Rat: Pathogenetic Mechanisms and Preventive Efficacy of Inhibiting the Urokinase-Type Plasminogen Activator Receptor System.
Q43039163Diabetic maculopathy and retinopathy. Functional and sociomedical significance
Q37892915Diabetic microvascular complications: possible targets for improved macrovascular outcomes
Q33914589Effect of angiotensin II type 1 receptor blocker and angiotensin converting enzyme inhibitor on the intraocular growth factors and their receptors in streptozotocin-induced diabetic rats.
Q47093719Effects of quercetin on the expression of MCP-1, MMP-9 and VEGF in rats with diabetic retinopathy
Q38464030Hydration, fluid regulation and the eye: in health and disease
Q37644348Hypoxia-induced angiotensin II by the lactate-chymase-dependent mechanism mediates radioresistance of hypoxic tumor cells
Q38990297Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors
Q37884176Inflammation in diabetic retinopathy
Q33703836Inhibition of protein kinase C delta attenuates blood-retinal barrier breakdown in diabetic retinopathy
Q37580070Intracardiac renin-angiotensin system and myocardial repair/remodeling following infarction
Q50524854Investigation of barrier characteristics in the hyaloid-retinal vessel of zebrafish.
Q58748151Local angiotensin II contributes to tumor resistance to checkpoint immunotherapy
Q57750182Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction
Q37678807Mediators of ocular angiogenesis
Q34766422Microvascular responses to cardiovascular risk factors.
Q38050159Neuropeptides and diabetic retinopathy
Q37204025Non-traditional systemic treatments for diabetic retinopathy: an evidence-based review
Q64058295Perturbed Biochemical Pathways and Associated Oxidative Stress Lead to Vascular Dysfunctions in Diabetic Retinopathy
Q38940171Recent perspectives on the delivery of biologics to back of the eye.
Q50116104Relationship between G proteins coupled receptors and tight junctions
Q42098043Renin-Angiotensin system hyperactivation can induce inflammation and retinal neural dysfunction
Q43442634Resveratrol blocks diabetes-induced early vascular lesions and vascular endothelial growth factor induction in mouse retinas
Q99561828Retinal Physiology and Circulation: Effect of Diabetes
Q39238324Role of Tissue Renin-angiotensin System and the Chymase/angiotensin-(1-12) axis in the Pathogenesis of Diabetic Retinopathy
Q60301147Serum microRNA-221 as a biomarker for diabetic retinopathy in patients associated with type 2 diabetes
Q48623673Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.
Q35005977TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis
Q34096257The development of blood-retinal barrier during the interaction of astrocytes with vascular wall cells
Q50947386The effect of a systemic angiotensin receptor blocker on vascular endothelial growth factor in the vitreous of patients with proliferative diabetic retinopathy.
Q35226462The kallikrein-kinin system in diabetic retinopathy
Q34364177Validation of structural and functional lesions of diabetic retinopathy in mice
Q34066200Vascular dysfunction associated with type 2 diabetes and Alzheimer's disease: a potential etiological linkage
Q27028225Vitreous mediators in retinal hypoxic diseases

Search more.