Initiation of lytic DNA replication in Epstein-Barr virus: search for a common family mechanism.

scientific article

Initiation of lytic DNA replication in Epstein-Barr virus: search for a common family mechanism. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2217/FVL.09.69
P932PMC publication ID3314400
P698PubMed publication ID22468146
P5875ResearchGate publication ID223980818

P50authorAndrew J. RennekampQ41867401
P2093author name stringPaul M Lieberman
P2860cites workPhysical interaction between the herpes simplex virus 1 origin-binding protein and single-stranded DNA-binding protein ICP8.Q36533126
Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infectionQ40407545
Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment.Q40478598
Reactivation of latent Epstein-Barr virus by methotrexate: a potential contributor to methotrexate-associated lymphomasQ40491223
The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genomeQ40516561
The enhancer factor R of Epstein-Barr virus (EBV) is a sequence-specific DNA binding protein.Q40526858
A novel function for the Epstein-Barr virus transcription factor EB1/Zta: induction of transcription of the hIL-10 gene.Q40661688
Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fosQ40816920
Kaposi's sarcoma-associated herpesvirus K-bZIP protein is phosphorylated by cyclin-dependent kinasesQ40905981
Herpes simplex virus DNA replicationQ40912250
Characterization of the Epstein-Barr virus BALF2 promoterQ40916123
Gene expression from the ORF50/K8 region of Kaposi's sarcoma-associated herpesvirusQ40920505
A major DNA binding protein encoded by BALF2 open reading frame of Epstein-Barr virus (EBV) forms a complex with other EBV DNA-binding proteins: DNAase, EA-D, and DNA polymeraseQ41071211
Herpes simplex virus type 1 replication and recombinationQ41125595
Epstein-Barr virus single-stranded DNA-binding protein: purification, characterization, and action on DNA synthesis by the viral DNA polymerase.Q41174826
Activation of oriLyt, the lytic origin of DNA replication of Epstein-Barr virus, by BZLF1.Q41191436
The Epstein-Barr virus encoded cytokine viral interleukin-10 enhances transformation of human B lymphocytes.Q41273193
Localization of an origin of DNA replication within the TRS/IRS repeated region of the herpes simplex virus type 1 genomeQ41307956
A concatenated form of Epstein-Barr viral DNA in lymphoblastoid cell lines induced by transfection with BZLF1.Q41549923
Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene.Q41627244
Analysis of intrastrain recombination in herpes simplex virus type 1 strain 17 and herpes simplex virus type 2 strain HG52 using restriction endonuclease sites as unselected markers and temperature-sensitive lesions as selected markersQ41642716
Cooperation of EBV DNA Polymerase and EA-D(BMRFl)in vitro and colocalization in nuclei of infected cellsQ41668501
Detection of anti-Epstein-Barr-virus transactivator (ZEBRA) antibodies in sera from patients with nasopharyngeal carcinomaQ41675223
Investigation of the multimerization region of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) protein K-bZIP: the proposed leucine zipper region encodes a multimerization domain with an unusual structureQ41810341
Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA proteinQ41864450
Reconstitution of uracil DNA glycosylase-initiated base excision repair in herpes simplex virus-1Q41946552
Residues within the conserved helicase motifs of UL9, the origin-binding protein of herpes simplex virus-1, are essential for helicase activity but not for dimerization or origin binding activityQ42055414
Assembly of the epstein-barr virus BBLF4, BSLF1 and BBLF2/3 proteins and their interactive propertiesQ42057658
Association of origin binding protein and single strand DNA-binding protein, ICP8, during herpes simplex virus type 1 DNA replication in vivo.Q42067607
The Epstein-Barr virus BMRF1 gene is essential for lytic virus replicationQ42124292
A Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50 deletion mutant is defective for reactivation of latent virus and DNA replicationQ42150768
Stepwise evolution of the herpes simplex virus origin binding protein and origin of replicationQ42231478
The major herpes simplex virus type-1 DNA-binding protein is a zinc metalloproteinQ42613072
Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44).Q42661164
Replicative forms of human cytomegalovirus DNA with joined termini are found in permissively infected human cells but not in non-permissive Balb/c-3T3 mouse cellsQ42823898
Xeroderma pigmentosum C is involved in Epstein Barr virus DNA replicationQ24300877
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathwayQ24316207
RNA-dependent recruitment of the origin recognition complexQ24336965
Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytesQ24338522
The Epstein-Barr virus replication protein BBLF2/3 provides an origin-tethering function through interaction with the zinc finger DNA binding protein ZBRK1 and the KAP-1 corepressorQ24558692
Herpes simplex virus type 1 ICP8: helix-destabilizing propertiesQ24644324
The IRF family, revisitedQ24678497
The herpes simplex virus type 1 alkaline nuclease and single-stranded DNA binding protein mediate strand exchange in vitroQ24683248
Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA.Q24813107
A bridge crosses the active-site canyon of the Epstein-Barr virus nuclease with DNase and RNase activitiesQ27656045
Reactivation of Epstein-Barr virus from latencyQ27728174
Epstein-Barr virus lytic infection induces retinoic acid-responsive genes through induction of a retinol-metabolizing enzyme, DHRS9Q28284628
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growthQ28389589
Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch proteinQ28472387
Epstein-Barr virus: 40 years onQ29617969
Analysis of human cytomegalovirus oriLyt sequence requirements in the context of the viral genomeQ30320280
The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replicationQ31032266
In vivo dynamics of EBNA1-oriP interaction during latent and lytic replication of Epstein-Barr virusQ31122638
Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage respoQ33201426
Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.Q33202888
A human cellular protein activity (OF-1), which binds herpes simplex virus type 1 origin, contains the Ku70/Ku80 heterodimerQ33204256
Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infectionQ33245944
A molecular link between malaria and Epstein-Barr virus reactivationQ33287194
Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replicationQ33321474
Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promotersQ33422971
Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein-Barr virus replication compartmentsQ33433812
The Epstein-Barr virus early protein EB1 activates transcription from different responsive elements including AP-1 binding sitesQ33565012
Epstein-Barr virus bicistronic mRNAs generated by facultative splicing code for two transcriptional trans-activatorsQ33567052
Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding proteinQ33634580
Properties of two 5'-coterminal RNAs transcribed part way and across the S component origin of DNA synthesis of the herpes simplex virus 1 genomeQ33669860
Human-herpesvirus-8-encoded K8 protein colocalizes with the promyelocytic leukemia protein (PML) bodies and recruits p53 to the PML bodiesQ43695707
Identification of a varicella-zoster virus origin of DNA replication and its activation by herpes simplex virus type 1 gene productsQ44250136
The herpes simplex virus type-1 single-strand DNA-binding protein (ICP8) promotes strand invasionQ44367835
Uracil in OriS of herpes simplex 1 alters its specific recognition by origin binding protein (OBP): does virus induced uracil-DNA glycosylase play a key role in viral reactivation and replication?Q44798850
Functional properties of the herpes simplex virus type I origin-binding protein are controlled by precise interactions with the activated form of the origin of DNA replicationQ44888122
Intermolecular recombination of the herpes simplex virus type 1 genome analysed using two strains differing in restriction enzyme cleavage sitesQ45034763
Structural features of the single-stranded DNA-binding protein of Epstein-Barr virusQ45398775
Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA proteinQ45419685
Detection of Epstein-Barr virus BGLF4 protein kinase in virus replication compartments and virus particles.Q45422376
TATA-binding protein and TBP-associated factors during herpes simplex virus type 1 infection: localization at viral DNA replication sitesQ45422778
Exposure to holoendemic malaria results in elevated Epstein-Barr virus loads in childrenQ45496126
Site-directed mutagenesis in a conserved motif of Epstein-Barr virus DNase that is homologous to the catalytic centre of type II restriction endonucleasesQ45729005
The Epstein-Barr virus (EBV) DNA polymerase accessory protein, BMRF1, activates the essential downstream component of the EBV oriLytQ45763509
G0/G1 growth arrest mediated by a region encompassing the basic leucine zipper (bZIP) domain of the Epstein-Barr virus transactivator Zta.Q45766038
Visualization of the unwinding of long DNA chains by the herpes simplex virus type 1 UL9 protein and ICP8.Q45770687
Herpes simplex virus 1 single-strand DNA-binding protein (ICP8) will promote homologous pairing and strand transferQ45775171
Demonstration of circularization of herpes simplex virus DNA following infection using pulsed field gel electrophoresisQ45778024
Herpes simplex virus replicative concatemers contain L components in inverted orientationQ45780769
Characterization of Epstein-Barr virus DNase and its interaction with the major DNA binding proteinQ45785783
Characterization of the TRs/IRS origin of DNA replication of herpes simplex virus Type 1Q45797434
Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virusQ45840879
The origin binding protein of herpes simplex virus 1 binds cooperatively to the viral origin of replication oris.Q45850832
Characterization of 3′-to-5′ exonuclease activity associated with Epstein-Barr virus DNA polymeraseQ45854815
The herpes simplex virus 1 origin binding protein: a DNA helicaseQ45855769
Human cytomegalovirus UL84 is a phosphoprotein that exhibits UTPase activity and is a putative member of the DExD/H box family of proteinsQ46390935
Properties of a primer RNA-DNA hybrid at the mouse mitochondrial DNA leading-strand origin of replicationQ46714810
Epstein-Barr virus-associated B-cell lymphoma in a patient with DNA ligase IV (LIG4) syndromeQ64388079
Inversion events in the HSV-1 genome are directly mediated by the viral DNA replication machinery and lack sequence specificityQ69832837
Study of the structure of replicative intermediates of HSV-1 DNA by pulsed-field gel electrophoresisQ72410005
CCAAT/enhancer-binding protein-alpha is induced during the early stages of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic cycle reactivation and together with the KSHV replication and transcription activator (RTA) cooperatively stimulates theQ73802773
Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP)Q76368260
Evidence that the herpes simplex virus type 1 uracil DNA glycosylase is required for efficient viral replication and latency in the murine nervous systemQ36624601
RNA polymerase II is aberrantly phosphorylated and localized to viral replication compartments following herpes simplex virus infectionQ36627034
cis-acting elements in the lytic origin of DNA replication of Epstein-Barr virusQ36650262
Renaturation of complementary DNA strands by herpes simplex virus type 1 ICP8.Q36654815
Herpes simplex virus type 1 recombination: role of DNA replication and viral a sequencesQ36656071
Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: cis-acting requirements for replication and ori-Lyt-associated RNA transcriptionQ36684599
Herpes simplex virus origin-binding protein (UL9) loops and distorts the viral replication originQ36695537
Purification and characterization of UL9, the herpes simplex virus type 1 origin-binding proteinQ36698650
Using or abusing: viruses and the cellular DNA damage responseQ36726902
Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fosQ36783282
Rolling circle DNA replication by extracts of herpes simplex virus type 1-infected human cellsQ36790103
Concatameric replication of Epstein-Barr virus: structure of the termini in virus-producer and newly transformed cell linesQ36793227
Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain terminationQ36796269
Recombinogenic properties of herpes simplex virus type 1 DNA sequences resident in simian virus 40 minichromosomesQ36799354
The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions.Q36802153
In vitro transcriptional activation, dimerization, and DNA-binding specificity of the Epstein-Barr virus Zta proteinQ36806719
The Epstein-Barr virus Zta transactivator: a member of the bZIP family with unique DNA-binding specificity and a dimerization domain that lacks the characteristic heptad leucine zipper motif.Q36810420
Responsiveness of the Epstein-Barr virus NotI repeat promoter to the Z transactivator is mediated in a cell-type-specific manner by two independent signal regionsQ36829336
The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle.Q36829427
Sequence and structural requirements of a herpes simplex viral DNA replication originQ36846133
Herpes simplex virus 1 recombinants with noninverting genomes frozen in different isomeric arrangements are capable of independent replicationQ36865235
A 67-base-pair segment from the Ori-S region of herpes simplex virus type 1 encodes origin functionQ36872106
Characterization of major recognition sequences for a herpes simplex virus type 1 origin-binding protein.Q36881646
Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesisQ36888407
Fusion of the termini of the murine cytomegalovirus genome after infectionQ36894352
A noninverting genome of a viable herpes simplex virus 1: presence of head-to-tail linkages in packaged genomes and requirements for circularization after infectionQ36898224
An immunoassay for the study of DNA-binding activities of herpes simplex virus protein ICP8.Q36902021
Association of Epstein-Barr virus early antigen diffuse component and virus-specified DNA polymerase activity.Q36918907
The herpes simplex virus origins of DNA synthesis in the S component are each contained in a transcribed open reading frame.Q36919492
Human cytomegalovirus origin of DNA replication (oriLyt) resides within a highly complex repetitive regionQ37051574
Kaposi's sarcoma-associated herpesvirus K-bZIP protein is necessary for lytic viral gene expression, DNA replication, and virion production in primary effusion lymphoma cell linesQ37191933
Protein array identification of substrates of the Epstein-Barr virus protein kinase BGLF4Q37192108
Identification and functional characterization of the left origin of lytic replication of murine gammaherpesvirus 68.Q37275510
Epstein-Barr virus polymerase processivity factor enhances BALF2 promoter transcription as a coactivator for the BZLF1 immediate-early protein.Q37372076
Replication of herpes simplex virus DNA.Q33738431
The Epstein-Barr virus lytic transactivator Zta interacts with the helicase-primase replication proteins.Q33785198
Genetic dissection of cell growth arrest functions mediated by the Epstein-Barr virus lytic gene product, ZtaQ33822549
Origin-independent assembly of Kaposi's sarcoma-associated herpesvirus DNA replication compartments in transient cotransfection assays and association with the ORF-K8 protein and cellular PML.Q33836726
Herpesvirus lytic replication and the cell cycle: arresting new developmentsQ33840180
BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186.Q33843046
The Kaposi's sarcoma-associated herpesvirus K8 protein interacts with CREB-binding protein (CBP) and represses CBP-mediated transcription.Q33846061
Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoterQ33880983
Cellular transcription factors recruit viral replication proteins to activate the Epstein-Barr virus origin of lytic DNA replication, oriLytQ33891311
Recombination and linkage between structural and regulatory genes of herpes simplex virus type 1: study of the functional organization of the genomeQ33920722
DNA repair proteins affect the lifecycle of herpes simplex virus 1.Q33936284
Site-directed mutagenesis of large DNA palindromes: construction and in vitro characterization of herpes simplex virus type 1 mutants containing point mutations that eliminate the oriL or oriS initiation functionQ34045705
A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus.Q34061465
Lytic replication-associated protein (RAP) encoded by Kaposi sarcoma-associated herpesvirus causes p21CIP-1-mediated G1 cell cycle arrest through CCAAT/enhancer-binding protein-alphaQ34075550
Epstein-Barr virus lytic infection is required for efficient production of the angiogenesis factor vascular endothelial growth factor in lymphoblastoid cell linesQ34123922
Epstein-Barr virus lytic infection contributes to lymphoproliferative disease in a SCID mouse modelQ34123985
K-bZIP of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) binds KSHV/HHV-8 Rta and represses Rta-mediated transactivationQ34180268
Origin-specific unwinding of herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: visualization of a specific preunwinding complexQ34328023
Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains two functional lytic origins of DNA replicationQ34343562
The crystal structure of the herpes simplex virus 1 ssDNA-binding protein suggests the structural basis for flexible, cooperative single-stranded DNA bindingQ34362280
CCAAT/enhancer binding protein alpha interacts with ZTA and mediates ZTA-induced p21(CIP-1) accumulation and G(1) cell cycle arrest during the Epstein-Barr virus lytic cycle.Q34465924
Helicase motif Ia is involved in single-strand DNA-binding and helicase activities of the herpes simplex virus type 1 origin-binding protein, UL9.Q34471081
DNA binding activity of the herpes simplex virus type 1 origin binding protein, UL9, can be modulated by sequences in the N terminus: correlation between transdominance and DNA binding.Q34647368
An initial ATP-independent step in the unwinding of a herpes simplex virus type I origin of replication by a complex of the viral origin-binding protein and single-strand DNA-binding proteinQ34692021
Kaposi's Sarcoma-Associated Herpesvirus Lytic Origin ( ori-Lyt )-Dependent DNA Replication: Identification of the ori-Lyt and Association of K8 bZip Protein with the OriginQ34976942
Direct BRLF1 binding is required for cooperative BZLF1/BRLF1 activation of the Epstein-Barr virus early promoter, BMRF1.Q34981036
Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta.Q35023745
Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replicationQ35101480
Herpes Virus ReplicationQ35115308
bZIP proteins of human gammaherpesviruses.Q35179637
Cell cycle arrest by Kaposi's sarcoma-associated herpesvirus replication-associated protein is mediated at both the transcriptional and posttranslational levels by binding to CCAAT/enhancer-binding protein alpha and p21(CIP-1)Q35182098
Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: dual role of replication and transcription activatorQ35185944
Structure of replicating herpes simplex virus DNAQ35242698
Herpes simplex virus DNA replication: a spacer sequence directs the ATP-dependent formation of a nucleoprotein complex at oriS.Q35255332
A DNA binding protein specific for an origin of replication of herpes simplex virus type 1.Q37396712
A method for identifying the viral genes required for herpesvirus DNA replicationQ37409686
Drug targets in herpes simplex and Epstein Barr Virus infectionsQ37411587
CCAAT/enhancer binding protein alpha binds to the Epstein-Barr virus (EBV) ZTA protein through oligomeric interactions and contributes to cooperative transcriptional activation of the ZTA promoter through direct binding to the ZII and ZIIIB motifs dQ37422745
Anatomy of Herpes Simplex Virus DNA. VIII. Properties of the Replicating DNAQ37506702
Characterization of a viable, noninverting herpes simplex virus 1 genome derived by insertion and deletion of sequences at the junction of components L and S.Q37610655
Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNAQ37691656
The structure and isomerization of herpes simplex virus genomesQ37975930
Replication of Epstein-Barr virus oriLyt: lack of a dedicated virally encoded origin-binding protein and dependence on Zta in cotransfection assays.Q38296033
Cellular proteins bind to the downstream component of the lytic origin of DNA replication of Epstein-Barr virusQ38298210
Unwinding of a herpes simplex virus type 1 origin of replication (Ori(S)) by a complex of the viral origin binding protein and the single-stranded DNA binding proteinQ38312028
A novel conformation of the herpes simplex virus origin of DNA replication recognized by the origin binding proteinQ38315290
The lytic origin of herpesvirus papio is highly homologous to Epstein-Barr virus ori-Lyt: evolutionary conservation of transcriptional activation and replication signalsQ38317840
trans-acting requirements for replication of Epstein-Barr virus ori-LytQ38327288
Epstein-Barr virus BZLF1 transactivator is a negative regulator of JunQ38327303
Primer terminus recognition and highly processive replication by Epstein-Barr virus DNA polymeraseQ38331823
Overexpression, purification and helix-destabilizing properties of Epstein-Barr virus ssDNA-binding proteinQ38337266
Herpes simplex virus DNA synthesis at a preformed replication fork in vitroQ38338972
Two binding sites for the herpes simplex virus type 1 UL9 protein are required for efficient activity of the oriS replication originQ38340668
Structure and function of the Epstein-Barr virus BZLF1 proteinQ38341018
Down-regulation of MHC class II expression through inhibition of CIITA transcription by lytic transactivator Zta during Epstein-Barr virus reactivationQ38356764
ATP-dependent unwinding of a minimal origin of DNA replication by the origin-binding protein and the single-strand DNA-binding protein ICP8 from herpes simplex virus type I.Q38363620
Evaluation of the lytic origins of replication of Kaposi's sarcoma-associated virus/human herpesvirus 8 in the context of the viral genomeQ38760706
Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase.Q39548922
Identification of persistent RNA-DNA hybrid structures within the origin of replication of human cytomegalovirus.Q39580006
Human cytomegalovirus oriLyt sequence requirementsQ39580752
The Epstein-Barr virus pol catalytic subunit physically interacts with the BBLF4-BSLF1-BBLF2/3 complexQ39589748
Machinery to support genome segment inversion exists in a herpesvirus which does not naturally contain invertible elementsQ39591243
Requirement for uracil-DNA glycosylase during the transition to late-phase cytomegalovirus DNA replicationQ39606506
Interaction with the Epstein-Barr virus helicase targets Zta to DNA replication compartmentsQ39607106
A particular DNA structure is required for the function of a cis-acting component of the Epstein-Barr virus OriLyt origin of replicationQ39719610
Identification of cis sequences required for lytic DNA replication and packaging of murine gammaherpesvirus 68.Q39754873
Human cytomegalovirus UL84 oligomerization and heterodimerization domains act as transdominant inhibitors of oriLyt-dependent DNA replication: evidence that IE2-UL84 and UL84-UL84 interactions are required for lytic DNA replicationQ39755438
Role for G-quadruplex RNA binding by Epstein-Barr virus nuclear antigen 1 in DNA replication and metaphase chromosome attachmentQ39816429
Functional interaction between Epstein-Barr virus replication protein Zta and host DNA damage response protein 53BP1.Q39816470
Interaction of HCMV UL84 with C/EBPalpha transcription factor binding sites within oriLyt is essential for lytic DNA replicationQ39821070
Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 K-bZIP modulates latency-associated nuclear protein-mediated suppression of lytic origin-dependent DNA synthesisQ39833695
Topoisomerase I and RecQL1 function in Epstein-Barr virus lytic reactivationQ39843185
The M10 locus of murine gammaherpesvirus 68 contributes to both the lytic and the latent phases of infectionQ39843210
Branched structures in the intracellular DNA of herpes simplex virus type 1.Q39874400
Plasmid-like replicative intermediates of the Epstein-Barr virus lytic origin of DNA replicationQ39874515
The Epstein-Barr virus alkaline exonuclease BGLF5 serves pleiotropic functions in virus replicationQ39876597
Cellular transcription factors Sp1 and Sp3 suppress varicella-zoster virus origin-dependent DNA replication.Q39936103
Concatemeric forms of intracellular herpesvirus DNAQ39982068
Replicating DNA of herpes simplex virus type 1.Q40033201
Human cytomegalovirus DNA replicates after early circularization by concatemer formation, and inversion occurs within the concatemerQ40039019
Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis.Q40044769
Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication.Q40048289
Multicomponent origin of cytomegalovirus lytic-phase DNA replicationQ40059070
Boundaries and structure of human cytomegalovirus oriLyt, a complex origin for lytic-phase DNA replicationQ40065708
Overexpression of the kaposi's sarcoma-associated herpesvirus transactivator K-Rta can complement a K-bZIP deletion BACmid and yields an enhanced growth phenotypeQ40072559
Replication of herpesvirus DNA II. Sedimentation characteristics of newly synthesized DNAQ40076271
Transcriptional repression of K-Rta by Kaposi's sarcoma-associated herpesvirus K-bZIP is not required for oriLyt-dependent DNA replicationQ40077471
Purification and properties of Epstein-Barr virus DNase expressed in Escherichia coliQ40107262
trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragmentQ40125966
Herpes simplex virus infection generates large tandemly reiterated simian virus 40 DNA molecules in a transformed hamster cell line.Q40132227
Complexities associated with expression of Epstein-Barr virus (EBV) lytic origins of DNA replicationQ40137307
Human cytomegalovirus disrupts both ataxia telangiectasia mutated protein (ATM)- and ATM-Rad3-related kinase-mediated DNA damage responses during lytic infectionQ40199767
Human cytomegalovirus DNA replication requires transcriptional activation via an IE2- and UL84-responsive bidirectional promoter element within oriLytQ40212902
Potential role for p53 in the permissive life cycle of human cytomegalovirusQ40243174
Deregulation of DNA damage signal transduction by herpesvirus latency-associated M2.Q40274368
Epstein-Barr virus protein kinase BGLF4 is a virion tegument protein that dissociates from virions in a phosphorylation-dependent process and phosphorylates the viral immediate-early protein BZLF1.Q40280193
Postreplicative mismatch repair factors are recruited to Epstein-Barr virus replication compartmentsQ40309902
Regulation of the expression of the Epstein-Barr virus early gene BFRF1.Q40331535
A redox-sensitive cysteine in Zta is required for Epstein-Barr virus lytic cycle DNA replicationQ40361661
Circularization of the herpes simplex virus type 1 genome upon lytic infectionQ40373850
DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein.Q35564463
The role of DNA recombination in herpes simplex virus DNA replication.Q35580375
Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP.Q35635192
Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replicationQ35635277
Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisomeQ35665398
Existence of transdominant and potentiating mutants of UL9, the herpes simplex virus type 1 origin-binding protein, suggests that levels of UL9 protein may be regulated during infectionQ35802817
Herpes simplex virus type 1 DNA replication is specifically required for high-frequency homologous recombination between repeated sequences.Q35839093
Structure and role of the terminal repeats of Epstein-Barr virus in processing and packaging of virion DNAQ35839124
The herpes simplex virus type 1 origin-binding protein carries out origin specific DNA unwinding and forms stem-loop structuresQ35847546
Interactions of viruses with the cellular DNA repair machineryQ35848546
The Epstein-Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin-dependent kinase inhibitorsQ35851139
Live covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interactionQ35857328
Epstein-Barr virus-encoded protein kinase (BGLF4) is involved in production of infectious virusQ35857562
Functional and physical interactions between the Epstein-Barr virus (EBV) proteins BZLF1 and BMRF1: Effects on EBV transcription and lytic replicationQ35865903
The variable 3' ends of a human cytomegalovirus oriLyt transcript (SRT) overlap an essential, conserved replicator element.Q35866094
Rolling circle DNA replication in vitro by a complex of herpes simplex virus type 1-encoded enzymesQ35868048
Evidence that the UL84 gene product of human cytomegalovirus is essential for promoting oriLyt-dependent DNA replication and formation of replication compartments in cotransfection assaysQ35871538
Use of transdominant mutants of the origin-binding protein (UL9) of herpes simplex virus type 1 to define functional domains.Q35872311
Association of herpes simplex virus regulatory protein ICP22 with transcriptional complexes containing EAP, ICP4, RNA polymerase II, and viral DNA requires posttranslational modification by the U(L)13 proteinkinase.Q35876535
Human cytomegalovirus UL84 interacts with an RNA stem-loop sequence found within the RNA/DNA hybrid region of oriLytQ35914395
Reconstitution of recombination-dependent DNA synthesis in herpes simplex virus 1Q35917688
Unwinding of the box I element of a herpes simplex virus type 1 origin by a complex of the viral origin binding protein, single-strand DNA binding protein, and single-stranded DNA.Q36071486
On the mechanism of strand assimilation by the herpes simplex virus type-1 single-strand DNA-binding protein (ICP8)Q36079364
The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivatorsQ36079854
Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replicationQ36082611
Transcription factors and DNA replication origin selectionQ36291781
Complementary intrastrand base pairing during initiation of Herpes simplex virus type 1 DNA replicationQ36298257
Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replicationQ36312310
The pleiotropic effects of Kaposi's sarcoma herpesvirusQ36346099
Viral interleukin 10 is critical for the induction of B cell growth transformation by Epstein-Barr virusQ36362069
Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: involvement of host cellular factorsQ36484112
Anatomy of Herpes Simplex Virus DNA XII. Accumulation of Head-to-Tail Concatemers in Nuclei of Infected Cells and Their Role in the Generation of the Four Isomeric Arrangements of Viral DNAQ36492840
Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cellsQ36498181
P433issue1
P921main subjectEpstein–Barr virusQ6900
P304page(s)65-83
P577publication date2010-01-01
P1433published inFuture VirologyQ15751230
P1476titleInitiation of lytic DNA replication in Epstein-Barr virus: search for a common family mechanism
P478volume5

Reverse relations

cites work (P2860)
Q36062461An Epstein-Barr Virus-Encoded Protein Complex Requires an Origin of Lytic Replication In Cis to Mediate Late Gene Transcription
Q34688796Chlamydia trachomatis infection induces replication of latent HHV-6
Q31063997Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo
Q42737581Evidence for DNA hairpin recognition by Zta at the Epstein-Barr virus origin of lytic replication
Q39614606Initiation of Epstein-Barr virus lytic replication requires transcription and the formation of a stable RNA-DNA hybrid molecule at OriLyt
Q42180912Molecular principles of human virus protein-protein interactions
Q38301018Recombination in viruses: mechanisms, methods of study, and evolutionary consequences.
Q36497017Telomeres and viruses: common themes of genome maintenance.

Search more.