Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes

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Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes is …
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scholarly articleQ13442814

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P819ADS bibcode1992PNAS...89.1890R
P356DOI10.1073/PNAS.89.5.1890
P3181OpenCitations bibliographic resource ID1551857
P932PMC publication ID48559
P698PubMed publication ID1371884
P5875ResearchGate publication ID21783596

P50authorFrancois RoussetQ55175960
Thierry DefranceQ62669243
Jacques BanchereauQ55097670
P2093author name stringD H Hsu
K W Moore
E Garcia
R Kastelein
N Vezzio
C Péronne
P2860cites workEvidence for compartmentalization of functional subsets of CD2+ T lymphocytes in atopic patientsQ68090119
Regulation of human IgE synthesis. I. Human IgE synthesis in vitro is determined by the reciprocal antagonistic effects of interleukin 4 and interferon-gammaQ68411976
Activation of human B lymphocytes through CD40 and interleukin 4Q69099068
Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clonesQ70030269
B cell growth-promoting activity of recombinant human interleukin 4Q70349955
Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFIQ24312126
Molecular cloning and expression of a human B-cell growth factor gene in Escherichia coliQ28300438
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteinsQ29547534
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional propertiesQ29547848
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clonesQ29622840
CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cellsQ30442717
Effect of tumor necrosis factor alpha on mitogen-activated human B cellsQ36353905
Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cellsQ36354177
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cellsQ36355239
Detection of human cytokine-secreting cells in distinct anatomical compartmentsQ37338075
Polyclonal Ig production after Epstein-Barr virus infection of human lymphocytes in vitroQ40068213
Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigenQ41694124
Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40Q41700086
Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1.Q41715014
Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.Q41731198
Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2.Q42111797
Cloned and expressed human Fc receptor for IgG mediates anti-CD3-dependent lymphoproliferationQ42123524
The short unique region of the B95-8 Epstein-Barr virus genomeQ42129046
Accumulation of Th-2-like helper T cells in the conjunctiva of patients with vernal conjunctivitisQ44570503
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
interleukin 10Q423698
lymphocyteQ715347
growth factor activityQ14820601
P304page(s)1890-1893
P577publication date1992-03-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInterleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
P478volume89

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Q40746828IL-10 restricts memory T cell inflation during cytomegalovirus infection
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Q36366415Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans
Q41065092In vitro culture of B-lymphocytes derived from Epstein-Barr-virus-associated posttransplant lymphoproliferative disease: cytokine production and effect of interferon-alpha
Q43796404In vitro cytokine production of TNFalpha and IL-13 correlates with acute liver transplant rejection
Q77579828In vitro production of IgG4 by peripheral blood mononuclear cells (PBMC): the contribution of committed B cells
Q53702693In vivo production of interleukin-10 by malignant cells in AIDS lymphomas.
Q34725050Inactivation of Myc in murine two-hit B lymphomas causes dormancy with elevated levels of interleukin 10 receptor and CD20: implications for adjuvant therapies
Q71069059Increase of intracellular calcium is the essential signal for the expression of CD40 ligand
Q70646324Increased expression of interferon-gamma in hyperplastic lymph nodes from HIV-infected patients
Q73128900Increased levels of circulating acetylcholine receptor (AChR)-reactive IL-10-secreting cells are characteristic for myasthenia gravis (MG)
Q73664184Increased synovial fluid levels of soluble CD23 are associated with an erosive status in rheumatoid arthritis (RA)
Q59548368Induction by anti-CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X-linked hyper IgM syndrome
Q33804544Induction of B-cell lymphoma by UVB radiation in p53 haploinsufficient mice
Q40877007Induction of chromosomal aberrations and growth-transformation of lymphoblastoid cell lines by inhibition of reactive oxygen species-induced apoptosis with interleukin-6.
Q28199765Induction, binding specificity and function of human ICOS
Q72687686Ineffective expression of CD40 ligand on cord blood T cells may contribute to poor immunoglobulin production in the newborn
Q37883443Inflamed gut mucosa: downstream of interleukin-10.
Q38169798Inflammatory and immune pathways in the pathogenesis of periodontal disease
Q42497733Inflammatory response in induced sputum mononuclear cells from patients with acute exacerbation of asthma
Q37684031Influence of interferon-alpha combined with chemo (radio) therapy on immunological parameters in pancreatic adenocarcinoma
Q92088185Influenza NG-34 T cell conserved epitope adjuvanted with CAF01 as a possible influenza vaccine candidate
Q53459609Inhibition of Interferon Regulatory Factor 4 Attenuates Acute Liver Allograft Rejection in Mice.
Q71754653Inhibition of the CD40-CD40ligand pathway prevents murine membranous glomerulonephritis
Q40412947Inhibitory receptors CD85j, LAIR-1, and CD152 down-regulate immunoglobulin and cytokine production by human B lymphocytes.
Q39914140Initiation of lytic DNA replication in Epstein-Barr virus: search for a common family mechanism.
Q38114912Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals
Q41949101Interferon gamma inhibits interleukin 10 production by monocytes
Q40220332Interferon-γ, interleukin-10 and interferon-inducible protein 10 (CXCL10) as serum biomarkers for the early allograft dysfunction after liver transplantation
Q24319022Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes
Q42943035Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses
Q42519209Interleukin 10 induced c-fos expression in human B cells by activation of divergent protein kinases
Q34234171Interleukin 10 induces B lymphocytes from IgA-deficient patients to secrete IgA.
Q42942120Interleukin 10 induces apoptotic cell death of B-chronic lymphocytic leukemia cells
Q36367452Interleukin 10 inhibits growth and granulocyte/macrophage colony-stimulating factor production in chronic myelomonocytic leukemia cells
Q35359662Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease
Q36361558Interleukin 10 protects mice from lethal endotoxemia
Q35579058Interleukin 10 treatment for rheumatoid arthritis
Q42075980Interleukin 13 is a B cell stimulating factor
Q35787936Interleukin-10 (IL-10) augments allograft arterial disease: paradoxical effects of IL-10 in vivo
Q43946365Interleukin-10 -1082 gene polymorphism and susceptibility to cervical cancer among Japanese women
Q50563241Interleukin-10 Production in Response to Amyloid-β Differs between Slow and Fast Decliners in Patients with Alzheimer's Disease.
Q40935346Interleukin-10 activates heat-shock protein 90beta gene expression
Q33647931Interleukin-10 and Gp130 cytokines in human multiple myeloma
Q40772002Interleukin-10 and cancer
Q34482930Interleukin-10 and transforming growth factor-beta promoter polymorphisms in allergies and asthma
Q47912619Interleukin-10 as a regulatory cytokine induced by cellular stress: molecular aspects
Q36517771Interleukin-10 concentration and coronary heart disease (CHD) event risk in the estrogen replacement and atherosclerosis (ERA) study
Q46299578Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling.
Q78524512Interleukin-10 expression after intramuscular DNA electrotransfer: kinetic studies
Q47605327Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response.
Q35187588Interleukin-10 from T cells, but not macrophages and granulocytes, is required for chronic disease in Leishmania mexicana infection
Q47763655Interleukin-10 gene expression and adult T-cell leukemia
Q74330009Interleukin-10 gene promoter polymorphism in Japanese patients with adult and early-onset periodontitis
Q41607039Interleukin-10 in non-Hodgkin's lymphoma
Q71552680Interleukin-10 in the vitreous of patients with primary intraocular lymphoma
Q28280073Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes
Q34235308Interleukin-10 inhibits apoptotic cell death in infectious mononucleosis T cells
Q72803272Interleukin-10 inhibits motility in murine and human B lymphocytes
Q52185000Interleukin-10 inhibits the in vitro proliferation of human activated leukemic CD5+ B-cells.
Q72345227Interleukin-10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells
Q34543328Interleukin-10 is expressed by bovine type 1 helper, type 2 helper, and unrestricted parasite-specific T-cell clones and inhibits proliferation of all three subsets in an accessory-cell-dependent manner.
Q35680472Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy
Q33493389Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein
Q41394260Interleukin-10 production by a B-cell line derived from human post-transplant lymphoproliferative disease
Q51972906Interleukin-10 promoter polymorphism in patients with rheumatoid arthritis.
Q47973471Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus
Q36860338Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx
Q52176801Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action.
Q71120290Interleukin-10 regulation in normal subjects and patients with asthma
Q33876788Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum.
Q33340529Interleukin-10 suppression of myeloid cell activation--a continuing puzzle
Q38523956Interleukin-10 up-regulates tumour-necrosis-factor-alpha-related apoptosis-inducing ligand (TRAIL) gene expression in mammary epithelial cells at the involution stage
Q87165829Interleukin-10-1082 gene polymorphism is associated with papillary thyroid cancer
Q33723684Interleukin-10: an anti-inflammatory cytokine with therapeutic potential
Q41684151Interleukin-10: biology, role in inflammation and autoimmunity
Q36978831Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells.
Q36376711Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome
Q33745148Intragraft expression of the IL-10 gene is up-regulated in renal protocol biopsies with early interstitial fibrosis, tubular atrophy, and subclinical rejection
Q35309325Intravitreal chemotherapy for the treatment of recurrent intraocular lymphoma
Q34671059Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
Q35056305Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment.
Q50049788Kinetics of viral load and cytokines in severe fever with thrombocytopenia syndrome
Q44088405LF 15-0195 prevents from the development and inhibits the progression of rat experimental autoimmune myasthenia gravis
Q54175860Lack of association between interleukin-10, transforming growth factor-beta gene polymorphisms and juvenile-onset systemic lupus erythematosus.
Q56519367Lactobacilli from human gastrointestinal mucosa are strong stimulators of IL-12 production
Q45883107Lentivirus-mediated gene transfer of viral interleukin-10 delays but does not prevent cardiac allograft rejection.
Q35552804Lipopolysaccharide and monophosphoryl lipid A differentially regulate interleukin-12, gamma interferon, and interleukin-10 mRNA production in murine macrophages.
Q58698634Liposomal nanoparticle-based conserved peptide influenza vaccine and monosodium urate crystal adjuvant elicit protective immune response in pigs
Q90533216Logistic Regression Classification of Primary Vitreoretinal Lymphoma versus Uveitis by Interleukin 6 and Interleukin 10 Levels
Q41291605Long-term survival of heart and liver xenografts with splenectomy and FK 506
Q42759877Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT-type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation
Q36329496M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production
Q34299710Macrophage cytokines: involvement in immunity and infectious diseases
Q41965237Mapping of the interleukin-10/interleukin-10 receptor combining site
Q77905787Markers in the promoter region of interleukin-10 (IL-10) gene in myasthenia gravis: implications of diverse effects of IL-10 in the pathogenesis of the disease
Q41300802Masters of deception: a review of herpesvirus immune evasion strategies
Q33205985Mechanisms in prostatitis/chronic pelvic pain syndrome
Q40628597Mediation of Enhanced Transcription of the IL-10 Gene in T Cells, Upon Contact with Human Glioma Cells, by Fas Signaling Through a Protein Kinase A-Independent Pathway
Q35666602Melatonin and viral infections
Q43743683Melatonin treatment enhances the efficiency of mice immunization with Venezuelan equine encephalomyelitis virus TC-83.
Q34340937Microbe-dependent CD11b+ IgA+ plasma cells mediate robust early-phase intestinal IgA responses in mice
Q71686319Mimicking the humoral immune response in vitro results in antigen-specific isotype switching supported by specific autologous T helper cells: generation of human HIV-1-neutralizing IgG monoclonal antibodies from naive donors
Q91911071Mixing ratio optimization for functional complex extracts of Rhodiola crenulata, Panax quinquefolius, and Astragalus membranaceus using mixture design and verification of immune functional efficacy in animal models
Q42709515Modulation of mite antigen‐induced immune responses by lecithin‐bound iodine in peripheral blood lymphocytes from patients with bronchial asthma
Q42854644Modulation of systemic antigen-specific immune responses by oral antigen in humans.
Q28272127Modulation of the human cytokine response by interferon lambda-1 (IFN-lambda1/IL-29)
Q35296982Molecular biomarkers for the diagnosis of primary vitreoretinal lymphoma
Q40392133Molecular control of B Lymphocyte growth and differentiation
Q34331092Molecular pathology of primary intraocular lymphoma
Q73608318Monocyte-derived IL-10-secreting dendritic cells in choroid plexus epithelium
Q35747533Multiple mechanisms of immune suppression by B lymphocytes
Q45392613Multiple sclerosis: reduced proportion of circulating plasmacytoid dendritic cells expressing BDCA-2 and BDCA-4 and reduced production of IL-6 and IL-10 in response to herpes simplex virus type 1.
Q50903174Murine immunomodulation of IL-10 and IL-12 induced by new isolates from avian type 2 Lactobacillus acidophilus.
Q40918922Myasthenia gravis: selective enrichment of antiacetylcholine receptor antibody production in untransformed human B cell cultures
Q34285220NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors
Q42517263Nasal epithelial cells express IL-10 at levels that negatively correlate with clinical symptoms in patients with house dust mite allergy
Q46418509Natural autoantibodies, IgG antibodies to tetanus toxoid and CD5+ B cells in patients with Mediterranean visceral leishmaniasis. The Leishmania Study Group
Q55041831Natural feline coronavirus infection: differences in cytokine patterns in association with the outcome of infection.
Q90214231Neonatal priming and infancy boosting with a novel respiratory syncytial virus vaccine induces protective immune responses without concomitant respiratory disease upon RSV challenge
Q35548444Neuropsychiatric systemic lupus erythematosus is associated with imbalance in interleukin 10 promoter haplotypes
Q92689063Neutralization of rhesus cytomegalovirus IL-10 reduces horizontal transmission and alters long-term immunity
Q57085803Neutralizing antibodies in multiple sclerosis patients treated with 375 μg interferon-β-1b
Q37409360Nonredundant roles for B cell-derived IL-10 in immune counter-regulation
Q37846865Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection
Q42611744Nucleotide sequence of a marsupial interleukin-10 cDNA from the Australian brushtail possum (Trichosurus vulpecula).
Q37403682Pathophysiology of retinal lymphoma
Q36190407Perspectives on common variable immune deficiency
Q50450148Phenotypic differences of CD4(+) T cells in response to red blood cell immunization in transfused sickle cell disease patients.
Q55266542Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus.
Q33856322Plasma cell generation from B-lymphocytes via CD27/CD70 interaction
Q45412251Plasmacytoid dendritic cells induce a distinct cytokine pattern in virus-specific CD4+ memory T cells that is modulated by CpG oligodeoxynucleotides
Q24317429Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6
Q87876744Polymorphism of IL-10 receptor β affects the prognosis of multiple myeloma patients treated with thalidomide and/or bortezomib
Q35791655Possible mechanisms of gender bias in SLE: a new hypothesis involving a comparison of SLE with atopy
Q40985093Post-transplant lymphoproliferative disease (PTLD): lymphokine production and PTLD.
Q43620498Pre-erythrocytic immunity to Plasmodium falciparum: the case for an LSA-1 vaccine
Q35018126Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression
Q42245915Prenatal vitamin A deficiency impairs adaptive immune responses to pentavalent rotavirus vaccine (RotaTeq®) in a neonatal gnotobiotic pig model
Q45365024Prevalence of Epstein-Barr virus in tonsils and adenoids of United Arab Emirates nationals
Q34875021Pro- and anti-inflammatory cytokines in human immunodeficiency virus infection and acquired immunodeficiency syndrome
Q41456685Production of interleukin-10 by human bronchogenic carcinoma.
Q35765267Production of the immunosuppressive cytokine interleukin-10 by Epstein-Barr-virus-expressing pyothorax-associated lymphoma: possible role in the development of overt lymphoma in immunocompetent hosts
Q41462121Proliferation and immunoglobulin secretion of lymphoblastoid cell lines are differently affected by soluble cytokines
Q72080497Purified excretory-secretory component of filarial parasite enhances Fc epsilon RII/CD23 expression on human splenic B and T cells and IgE synthesis while potentiating T-helper type 2-related cytokine generation from T cells
Q43196260Puumala virus RNA in patient with multiorgan failure
Q40231953Recombinant protein YbgF induces protective immunity against Rickettsia heilongjiangensis infection in C3H/HeN mice.
Q52007339Reduced IL-2-induced IL-12 responsiveness in atopic children.
Q82028854Regulation of T cells and cytokines by the interleukin-10 (IL-10)-family cytokines IL-19, IL-20, IL-22, IL-24 and IL-26
Q42490503Regulation of immunoglobulin secretion by plasma cells infiltrating nasal polyps
Q28477869Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase
Q73958152Regulation of mouse immuno-responses by a natural suppressor cell clone from bone marrow
Q41827353Regulation of production of mucosal antibody to pneumococcal protein antigens by T-cell-derived gamma interferon and interleukin-10 in children.
Q35685566Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo
Q34430587Relationship of Epstein-Barr virus and interleukin 10 promoter polymorphisms with the risk and clinical outcome of childhood Burkitt lymphoma.
Q73401710Repeated concanavalin A challenge in mice induces an interleukin 10-producing phenotype and liver fibrosis
Q37360750Requirement for increased IL-10 in the development of B-1 lymphoproliferative disease in a murine model of CLL.
Q54560299Retinoic acid enhances the production of IL-10 while reducing the synthesis of IL-12 and TNF-alpha from LPS-stimulated monocytes/macrophages.
Q34572250Rheumatoid arthritis and tumor necrosis factor alpha
Q71608295Role of CD40 antigen and interleukin-2 in T cell-dependent human B lymphocyte growth
Q90411093Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA Nephropathy
Q38176006Role of IL-10 in the progression of kidney disease
Q40237247Role of Interleukin-10 Gene Promoter Region Polymorphism in the Development of Chronic Lymphoid Leukemia.
Q56834786Role of Interleukin-10 in the Lung Response to Silica in Mice
Q36476646Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.
Q35986928Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing
Q36364479Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus
Q40403592Role of interleukin-4 and interleukin-13 in synthesis of IgE and expression of CD23 by human B cells
Q38060836Roles of IL-10 in ocular inflammations: a review.
Q36677337STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation.
Q24300242Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain
Q46758920Secretion of parasite-specific immunoglobulin G by purified blood B lymphocytes from immune individuals after in vitro stimulation with recombinant Plasmodium falciparum merozoite surface protein-119 antigen
Q35080072Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway
Q73899142Selective enhancement of endothelial cell VCAM-1 expression by interleukin-10 in the presence of activated leucocytes
Q61955175Serum IL-4, IL-10 and IL-6 levels in inflammatory arthritis
Q33561191Serum adiponectin as a predictor of childhood non-Hodgkin's lymphoma: a nationwide case-control study.
Q78099939Serum cytokines and increased total serum IgE in alcoholics
Q57332478Serum free light chains, interferon-alpha, and interleukins in systemic lupus erythematosus
Q57194426Serum interleukin 10 titers in systemic lupus erythematosus reflect disease activity
Q73202043Serum interleukin-10 in plasma-cell dyscrasias
Q73363940Serum levels of tetranectin, intercellular adhesion molecule-1 and interleukin-10 in B-chronic lymphocytic leukemia
Q33951480Sex hormones as immunomodulators in health and disease
Q34333361Sex hormones in experimental autoimmune encephalomyelitis: implications for multiple sclerosis
Q41332745Sex hormones modulate the immune response to Plasmodium berghei ANKA in CBA/Ca mice
Q33828605Short-lived IFN-γ effector responses, but long-lived IL-10 memory responses, to malaria in an area of low malaria endemicity
Q34199490Signaling through CD40 rescues IgE but not IgG or IgA secretion in X-linked immunodeficiency with hyper-IgM.
Q51743751Skin disease is prevented but nephritis is accelerated by multiple pregnancies in autoimmune MRL/LPR mice.
Q24669982Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes
Q45138741Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40-ligand) and TNF-alpha, but strongly enhanced by interleukin-10.
Q73833450Spontaneous expression of mRNA for IL-10, GM-CSF, TGF-beta, TGF-alpha, and IL-6 in peripheral blood mononuclear cells from atopic dermatitis
Q38351898Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain
Q38272620Stimulation of B lymphocytes by cmvIL-10 but not LAcmvIL-10
Q35925869Structural analysis of IL-10 and Type I interferon family members and their complexes with receptor
Q48350871Structural characterisation of the distal 5' flanking region of the human interleukin-10 gene
Q75231227Studies in NZB IL-10 knockout mice of the requirement of IL-10 for progression of B-cell lymphoma
Q45734684Suppressive effect of locally produced interleukin-10 on respiratory syncytial virus infection
Q33181349Switch from cyclosporine A to tacrolimus in renal transplant recipients: impact on Th1, Th2, and monokine responses
Q77394096Synergistic augmentative effect of interleukin-10 and CD27/CD70 interactions on B-cell immunoglobulin synthesis
Q38743752Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis.
Q37645635Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations
Q56906331Systemic lupus erythematosus candidate genes in the Italian population: evidence for a significant association with interleukin-10
Q36673286Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease.
Q35558638T cell subsets and their signature cytokines in autoimmune and inflammatory diseases
Q35828841T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue.
Q42747570T cells of the human intestinal lamina propria are high producers of interleukin-10.
Q45730577T-helper I immunity, specific for the breast cancer antigen insulin-like growth factor-I receptor (IGF-IR), is associated with increased adiposity
Q43493525T-helper cell-mediated interferon-gamma, interleukin-10 and proliferation responses to a candidate recombinant vaccine for human parvovirus B19.
Q37235039TLR-mediated stimulation of APC: Distinct cytokine responses of B cells and dendritic cells.
Q82627959TLR4 and MyD88 control protection and pulmonary granulocytic recruitment in a murine intranasal RSV immunization and challenge model
Q36071989TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism
Q37350439TNFA and IL10 gene polymorphisms are not associated with periodontitis in Brazilians.
Q37483143TRAF3 regulates the effector function of regulatory T cells and humoral immune responses
Q45944049Targeting IL-10 Family Cytokines for the Treatment of Human Diseases.
Q99588210Targeting of interleukin-10 receptor by a potential human interleukin-10 peptide efficiently blocks interleukin-10 pathway-dependent cell proliferation
Q42467538Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE).
Q24673258The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future
Q33882153The Epstein-Barr virus and its association with human cancers
Q35046770The IL-10 polarized cytokine pattern in innate and adaptive immunity cells contribute to the development of FVIII inhibitors
Q33326982The MHV68 M2 protein drives IL-10 dependent B cell proliferation and differentiation
Q34942368The Mycobacterium tuberculosis complex-restricted gene cfp32 encodes an expressed protein that is detectable in tuberculosis patients and is positively correlated with pulmonary interleukin-10.
Q47134266The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases
Q33187279The TNF family members BAFF and APRIL: the growing complexity
Q36667866The absence of M1 leads to increased establishment of murine gammaherpesvirus 68 latency in IgD-negative B cells
Q40385754The biology of the human ligand for CD40.
Q34203672The complex role of interleukin-10 in autoimmunity
Q52049146The differentiation of human memory B cells into specific antibody-secreting cells is CD40 independent.
Q38281273The dual nature of interleukin-10 in pemphigus vulgaris
Q73294557The effect of smokeless tobacco extract on murine T cell cytokine production
Q42520842The effects of CD40- and interleukin (IL-4)-activated CD23+ cells on the production of IL-10 by mononuclear cells in Graves' disease: the role of CD8+ cells
Q34148175The genetics of systemic lupus erythematosus: putting the pieces together
Q34315400The human interleukin-10 receptor gene maps to chromosome 11q23.3.
Q46061551The immune modulation of B-cell responses by Porphyromonas ginginvalis and interleukin-10.
Q83346423The immune modulation of Bacillus cereus var. Toyoi in mice immunized with experimental inactivated Bovine Herpesvirus Type 5 vaccine
Q35548182The immune suppressive effect of dexamethasone in rheumatoid arthritis is accompanied by upregulation of interleukin 10 and by differential changes in interferon gamma and interleukin 4 production
Q35809008The immunoregulatory and allergy-associated cytokines in the aetiology of the otitis media with effusion
Q41761209The immunosuppressive factors IL-10, TGF-β, and VEGF do not affect the antigen-presenting function of CD40-activated B cells
Q51084911The interplay between T helper subset cytokines and IL-12 in directing human B lymphocyte differentiation.
Q35810601The molecular basis of IL-10 function: from receptor structure to the onset of signaling
Q41853009The normal counterpart of IgD myeloma cells in germinal center displays extensively mutated IgVH gene, Cmu-Cdelta switch, and lambda light chain expression
Q40816643The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages
Q40603032The potential role of cytokines in the pathogenesis of Epstein-Barr virus associated post-transplant lymphoproliferative disease
Q37951500The regulation and role of T follicular helper cells in immunity
Q38956578The role of IL-29 in immunity and cancer.
Q37811046The role of SAP and SLAM family molecules in the humoral immune response
Q26775041The role of cytokines in the pathogenesis and staging of Trypanosoma brucei rhodesiense sleeping sickness
Q36703956The role of genetic polymorphisms in periodontitis
Q34148661The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS).
Q34203678The role of interleukin-10 in systemic lupus erythematosus
Q38298670The vIL-10 gene of the Epstein-Barr virus (EBV) is conserved in a stable manner except for a few point mutations in various EBV isolates
Q34767204Theodore E. Woodward Award: development of novel, EBV-targeted therapies for EBV-positive tumors
Q53650475Therapeutic effects of systemic vitamin k2 and vitamin d3 on gingival inflammation and alveolar bone in rats with experimentally induced periodontitis.
Q40779579Tracking membrane and secretory immunoglobulin alpha heavy chain mRNA variation during B-cell differentiation by real-time quantitative polymerase chain reaction.
Q34430041Trichodysplasia spinulosa-associated polyomavirus (TSV) and Merkel cell polyomavirus: correlation between humoral and cellular immunity stronger with TSV
Q71941651Tumor necrosis factor-alpha, lymphotoxin, interleukin (IL)-6, IL-10, IL-12 and perforin mRNA expression in mononuclear cells in response to acetylcholine receptor is augmented in myasthenia gravis
Q35787792Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients
Q33606814Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease
Q28554673Type I Interferons Induce T Regulatory 1 Responses and Restrict Humoral Immunity during Experimental Malaria
Q80109609Ultraviolet-A (UVA-1) radiation suppresses immunoglobulin production of activated B lymphocytes in vitro
Q36362069Viral interleukin 10 is critical for the induction of B cell growth transformation by Epstein-Barr virus
Q30436621Virus-encoded homologs of cellular interleukin-10 and their control of host immune function
Q38120519Why interleukin-10 supplementation does not work in Crohn's disease patients.
Q36911289vIL-10-overexpressing human MSCs modulate naïve and activated T lymphocytes following induction of collagenase-induced osteoarthritis

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