Cetuximab administered once every second week to patients with metastatic colorectal cancer: a two-part pharmacokinetic/pharmacodynamic phase I dose-escalation study.

scientific article published on 25 November 2009

Cetuximab administered once every second week to patients with metastatic colorectal cancer: a two-part pharmacokinetic/pharmacodynamic phase I dose-escalation study. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/ANNONC/MDP549
P698PubMed publication ID19940007

P50authorJosep Tabernero CaturlaQ37387600
Fortunato CiardielloQ43184447
Francisco J RamosQ77833971
P2093author name stringF Rivera
J Baselga
A Cervantes
T Macarulla
E Martinelli
S Roselló
S Liebscher
O Kisker
E Rodriguez-Braun
M E Vega-Villegas
P2860cites workNonparametric Estimation from Incomplete ObservationsQ25938997
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.Q27824811
Cetuximab for the treatment of colorectal cancer.Q27851419
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancerQ28240089
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancerQ28305293
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Biweekly cetuximab and irinotecan in advanced colorectal cancer patients progressing after at least one previous line of chemotherapy: results of a phase II single institution trial.Q36858054
Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II studyQ37182234
Structural basis for inhibition of the epidermal growth factor receptor by cetuximabQ45345151
FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.Q45949257
Pharmacokinetic profile of cetuximab (Erbitux) alone and in combination with irinotecan in patients with advanced EGFR-positive adenocarcinomaQ46624336
EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancerQ46662707
Biweekly cetuximab and irinotecan as third-line therapy in patients with advanced colorectal cancer after failure to irinotecan, oxaliplatin and 5-fluorouracilQ46748546
Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinomaQ46816802
P433issue7
P921main subjectcolorectal cancerQ188874
pharmacodynamicsQ725307
pharmacokineticsQ323936
cetuximabQ420296
colorectal carcinomaQ25493920
metastatic colon cancerQ108566365
P304page(s)1537-1545
P577publication date2009-11-25
P1433published inAnnals of OncologyQ326122
P1476titleCetuximab administered once every second week to patients with metastatic colorectal cancer: a two-part pharmacokinetic/pharmacodynamic phase I dose-escalation study
P478volume21

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cites work (P2860)
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