scholarly article | Q13442814 |
P50 | author | Patrizia Ballerini | Q114437495 |
Iolanda D'Alimonte | Q114437533 | ||
Michel P Rathbone | Q114437541 | ||
Shucui Jiang | Q114437546 | ||
Eva S Werstiuk | Q114437797 | ||
P2093 | author name string | Christian Bau | |
Kathleen M Pettifer | |||
P2860 | cites work | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation | Q24642901 |
Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein | Q26269955 | ||
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
Alpha-synuclein in Lewy bodies | Q27860680 | ||
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms | Q28137802 | ||
Mechanisms of caspase activation | Q28187994 | ||
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease | Q28210040 | ||
Pertussis toxin and target eukaryotic cells: binding, entry, and activation | Q28269020 | ||
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases | Q28269333 | ||
Cell death in the nervous system | Q28269343 | ||
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death | Q28278883 | ||
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate | Q28301966 | ||
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease | Q28594269 | ||
Parkinson's disease: mechanisms and models | Q29547424 | ||
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis | Q29547567 | ||
Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
Characterization and time course of MPP+ -induced apoptosis in human SH-SY5Y neuroblastoma cells | Q30303651 | ||
Rat brain guanosine binding site. Biological studies and pseudo-receptor construction. | Q31029356 | ||
Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells | Q32063604 | ||
Etiology and pathogenesis of Parkinson's disease | Q33593402 | ||
Nucleoside transporters: molecular biology and implications for therapeutic development | Q33632764 | ||
Apoptotic DNA fragmentation | Q33876750 | ||
Trophic effects of purines in neurons and glial cells. | Q33939094 | ||
Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria | Q33959022 | ||
Cell death induced by MPTP, a substrate for monoamine oxidase B. | Q34088858 | ||
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis | Q34132208 | ||
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway | Q34278037 | ||
G-protein-coupled receptors and signaling networks: emerging paradigms. | Q34296103 | ||
Caspase-independent cell death | Q34433759 | ||
Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes | Q34802158 | ||
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. | Q35083548 | ||
Targeting programmed cell death in neurodegenerative diseases | Q35120138 | ||
Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease | Q35171012 | ||
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease | Q35171029 | ||
Phosphoinositide 3-kinase signalling--which way to target? | Q35181798 | ||
The role of alpha-synuclein in Parkinson's disease: insights from animal models | Q35209957 | ||
Interrupting apoptosis in neurodegenerative disease: potential for effective therapy? | Q35674384 | ||
Death without caspases, caspases without death | Q35739290 | ||
Mitogen-activated protein kinases in apoptosis regulation | Q35743118 | ||
Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials. | Q35761616 | ||
Advances in protein kinase B signalling: AKTion on multiple fronts | Q35766370 | ||
Role of extracellular signal regulated kinases 1 and 2 in neuronal survival | Q35778135 | ||
Adult neuron survival strategies--slamming on the brakes | Q35868063 | ||
Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology | Q35874476 | ||
DNA degradation in development and programmed cell death | Q36072468 | ||
The MPTP model of Parkinson's disease | Q36080019 | ||
Molecular basis of programmed cell death involved in neurodegeneration | Q36282417 | ||
Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein | Q36295605 | ||
Akt regulates cell survival and apoptosis at a postmitochondrial level | Q36342570 | ||
Heterotrimeric G-proteins: a short history | Q36364445 | ||
Caspase function in programmed cell death | Q36643566 | ||
Mechanisms of disease: DNA repair defects and neurological disease | Q36753339 | ||
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining | Q36857701 | ||
Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity. | Q40463919 | ||
Guanosine protects SH-SY5Y cells against beta-amyloid-induced apoptosis | Q40568471 | ||
Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide | Q40595894 | ||
Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons | Q40599232 | ||
MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells | Q40725645 | ||
Complexity and diversity of mammalian adenylyl cyclases | Q41048221 | ||
1-methyl-4-phenyl-pyridinium ion (MPP+) causes DNA fragmentation and increases the Bcl-2 expression in human neuroblastoma, SH-SY5Y cells, through different mechanisms | Q41258866 | ||
Specific [(3)H]-guanosine binding sites in rat brain membranes | Q42021948 | ||
The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. | Q42460494 | ||
Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells | Q42490786 | ||
Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP. | Q42617687 | ||
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. | Q42800979 | ||
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease? | Q43548211 | ||
Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole | Q43574350 | ||
Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium | Q43786473 | ||
Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease | Q44013447 | ||
Do inducers of apoptosis trigger caspase-independent cell death? | Q45267818 | ||
Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway | Q47400542 | ||
Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells. | Q55068180 | ||
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease | Q64767727 | ||
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma | Q71970954 | ||
Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor | Q72121269 | ||
Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades | Q77322545 | ||
P433 | issue | 4 | |
P921 | main subject | cytotoxicity | Q246181 |
neuroblastoma | Q938205 | ||
P304 | page(s) | 399-409 | |
P577 | publication date | 2007-09-01 | |
P1433 | published in | Purinergic Signalling | Q15716545 |
P1476 | title | MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine | |
P478 | volume | 3 |
Q42372900 | Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder. |
Q37447674 | Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis |
Q47659411 | Curcumin affords neuroprotection and inhibits α-synuclein aggregation in lipopolysaccharide-induced Parkinson's disease model |
Q33569173 | Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model |
Q40466209 | Genetic modification of H2AX renders mesenchymal stromal cell-derived dopamine neurons more resistant to DNA damage and subsequent apoptosis. |
Q46814683 | Guanosine Protects Against Cortical Focal Ischemia. Involvement of Inflammatory Response. |
Q37256409 | Guanosine and its role in neuropathologies |
Q48295676 | Guanosine protects against reperfusion injury in rat brains after ischemic stroke |
Q28072158 | Guanosine: a Neuromodulator with Therapeutic Potential in Brain Disorders |
Q35073154 | Inhibition of store-operated calcium entry attenuates MPP(+)-induced oxidative stress via preservation of mitochondrial function in PC12 cells: involvement of Homer1a |
Q39437666 | Iridoids from the roots of Valeriana jatamansi and their biological activities |
Q35759141 | Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice. |
Q59127756 | Neuromodulatory Effects of Guanine-Based Purines in Health and Disease |
Q54581993 | Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition. |
Q95643364 | Novel Targets for Fast Antidepressant Responses: Possible Role of Endogenous Neuromodulators |
Q38736125 | Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage |
Q35109170 | The potential therapeutic effect of guanosine after cortical focal ischemia in rats. |
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