| P50 | author | Francisco Ciruela | Q59706012 |
| | Carla I Tasca | Q70879971 |
| | Débora Lanznaster | Q42314832 |
| P2093 | author name string | Victor Fernández-Dueñas | |
| | Karen A Oliveira | |
| P2860 | cites work | Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers | Q24304896 |
| | The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart | Q24540404 |
| | Adenosine receptors as therapeutic targets | Q24632095 |
| | Potential of Glutamate-Based Drug Discovery for Next Generation Antidepressants | Q26782274 |
| | The Effects of Psychological Stress on Depression | Q26786217 |
| | Guanosine: a Neuromodulator with Therapeutic Potential in Brain Disorders | Q28072158 |
| | Glutamate as a neurotransmitter in the brain: review of physiology and pathology | Q28139934 |
| | Quinolinic Acid Concentrations in Brain and Cerebrospinal Fluid of Patients with Intractable Complex Partial Seizures | Q28323245 |
| | Characterization of nucleotide transport into rat brain synaptic vesicles | Q28371756 |
| | Mechanisms and functional implications of adult neurogenesis | Q29547295 |
| | Mammalian neural stem cells | Q29547657 |
| | The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics | Q29614972 |
| | Serum urate as a predictor of clinical and radiographic progression in Parkinson disease | Q30440692 |
| | Rat brain guanosine binding site. Biological studies and pseudo-receptor construction. | Q31029356 |
| | Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia. | Q31113573 |
| | Glutamatergic neurotransmission in aging: a critical perspective. | Q31863146 |
| | Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression. | Q33552904 |
| | Etiology and pathogenesis of Parkinson's disease | Q33593402 |
| | Mechanisms involved in the antinociception induced by systemic administration of guanosine in mice. | Q33767200 |
| | Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome. | Q33807095 |
| | Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. | Q33892412 |
| | Trophic effects of purines in neurons and glial cells. | Q33939094 |
| | Purinergic nerves | Q34052179 |
| | Involvement of astrocytes in purine-mediated reparative processes in the brain | Q34264926 |
| | The potential therapeutic effect of guanosine after cortical focal ischemia in rats. | Q35109170 |
| | Targeting programmed cell death in neurodegenerative diseases | Q35120138 |
| | Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut. | Q35226290 |
| | G proteins | Q35557485 |
| | Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice. | Q35759141 |
| | Remyelination after chronic spinal cord injury is associated with proliferation of endogenous adult progenitor cells after systemic administration of guanosine | Q36464834 |
| | Proposal of a guanine-based purinergic system in the mammalian central nervous system. | Q36947502 |
| | Adenosine and ATP receptors in the brain | Q37852731 |
| | Role of purinergic receptors in CNS function and neuroprotection | Q37876550 |
| | The role of G proteins in transmembrane signalling. | Q37901376 |
| | G protein-coupled receptor oligomerization and brain integration: focus on adenosinergic transmission. | Q38009142 |
| | Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease | Q38016898 |
| | mGluRs head to toe in pain. | Q38368341 |
| | Guanosine inhibits LPS-induced pro-inflammatory response and oxidative stress in hippocampal astrocytes through the heme oxygenase-1 pathway | Q38830721 |
| | Gliopreventive effects of guanosine against glucose deprivation in vitro | Q39126996 |
| | Glutamine synthetase functions as a negative growth regulator in glioma | Q39137774 |
| | Protective activity of guanosine in an in vitro model of Parkinson's disease. | Q39217755 |
| | Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway. | Q39334402 |
| | Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers | Q39655164 |
| | Ammonia: key factor in the pathogenesis of hepatic encephalopathy | Q39667268 |
| | MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine | Q39959282 |
| | Guanosine promotes B16F10 melanoma cell differentiation through PKC-ERK 1/2 pathway | Q39985468 |
| | Neuroprotective effects of guanosine on stroke models in vitro and in vivo | Q40025719 |
| | Guanine derivatives modulate extracellular matrix proteins organization and improve neuron-astrocyte co-culture. | Q48155961 |
| | Effects of guanine nucleotides on adenosine and glutamate modulation of cAMP levels in optic tectum slices from chicks | Q48194906 |
| | Guanine nucleotides, including GMP, antagonize kainate responses in Xenopus oocytes injected with chick cerebellar membranes | Q48227374 |
| | Guanine-based purines modulate the effect of L-NAME on learning and memory in rats. | Q48229249 |
| | High levels of quinolinic acid in brain of epilepsy-prone E1 mice | Q48233373 |
| | Guanosine protects against reperfusion injury in rat brains after ischemic stroke | Q48295676 |
| | Purine nucleotides inhibit the binding of DL-[3H] 2-amino-4-phosphonobutyrate (DL-[3H] APB) to L-glutamate-sensitive sites on rat brain membranes | Q48366255 |
| | Multipotent progenitor cells in the adult dentate gyrus | Q48405038 |
| | In vitro oxygen-glucose deprivation to study ischemic cell death. | Q48445138 |
| | Effects of guanine nucleotides on glutamate-induced chemiluminescence in rat hippocampal slices submitted to hypoxia | Q48480083 |
| | Guanosine prevents behavioral alterations in the forced swimming test and hippocampal oxidative damage induced by acute restraint stress | Q48484990 |
| | Guanosine promotes the up-regulation of inward rectifier potassium current mediated by Kir4.1 in cultured rat cortical astrocytes | Q48485531 |
| | Guanine nucleotides inhibit cAMP accumulation induced by metabotropic glutamate receptor activation. | Q48527239 |
| | Guanosine Prevents Anhedonic-Like Behavior and Impairment in Hippocampal Glutamate Transport Following Amyloid-β1-40 Administration in Mice | Q48528502 |
| | Specific binding of [3H]GppNHp to extracellular membrane receptors in chick cerebellum: possible involvement of kainic acid receptors | Q48729826 |
| | Effects of guanine nucleotides on kainic acid binding and on adenylate cyclase in chick optic tectum and cerebellum | Q48830784 |
| | Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation | Q48921203 |
| | The antidepressant-like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation | Q48970988 |
| | Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats | Q49029381 |
| | Guanine deaminase from rat brain. Purification, characteristics, and contribution to ammoniagenesis in the brain | Q49072133 |
| | Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders | Q50420451 |
| | Interaction of adenosine and guanine derivatives in the rat hippocampus: effects on cyclic AMP levels and on the binding of adenosine analogues and GMP | Q73726116 |
| | Guanosine and GMP prevent seizures induced by quinolinic acid in mice | Q73740298 |
| | Guanine nucleotides are present in human CSF | Q74032433 |
| | Guanine nucleotides block agonist-driven 45Ca2+ influx in chick embryo retinal explants | Q74102477 |
| | Guanine nucleotides protect against kainate toxicity in an ex vivo chick retinal preparation | Q74831388 |
| | Allopurinol as adjunctive therapy in intractable epilepsy: a double-blind and placebo-controlled trial | Q79916626 |
| | Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines | Q80758439 |
| | Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen-glucose deprivation | Q81151883 |
| | The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains | Q82763217 |
| | Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake | Q83704482 |
| | Evidence for the existence of a specific g protein-coupled receptor activated by guanosine | Q83889177 |
| | Development of a new HPLC method using fluorescence detection without derivatization for determining purine nucleoside phosphorylase activity in human plasma | Q86999584 |
| | Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway | Q95445471 |
| | Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions. | Q50955863 |
| | Heterodimeric adenosine receptors: a device to regulate neurotransmitter release. | Q51114968 |
| | Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition. | Q54581993 |
| | Neurochemical analysis of focal ischemia in rats | Q67705253 |
| | Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo | Q69352295 |
| | Synaptosomal apyrase in the hypothalamus of adult rats | Q69358214 |
| | Effects of guanine nucleotides on N-methyl-D-aspartate receptor-ligand interactions | Q69836068 |
| | Potentiation of the chemotherapeutic action of 5'-deoxy-5-fluorouridine in combination with guanosine and related compounds | Q70165315 |
| | GTP and guanosine synergistically enhance NGF-induced neurite outgrowth from PC12 cells | Q71462197 |
| | Extracellular guanosine and guanosine-5′-triphosphate increase: NGF synthesis and release from cultured mouse neopallial astrocytes | Q71861786 |
| | Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms | Q71971294 |
| | Guanine nucleotides inhibit the stimulation of GFAP phosphorylation by glutamate | Q72252323 |
| | Regulation of cerebellar l-[3H]glutamate binding: influence of guanine nucleotides and Na+ ions | Q72514358 |
| | Failure of remyelination in areas of demyelination produced in the spinal cord of old rats | Q72792703 |
| | The role of glutamate in epilepsy and other CNS disorders | Q72829656 |
| | Differential effects of guanine nucleotides on kainic acid binding and on adenylate cyclase activity in chick optic tectum | Q72862547 |
| | Enhanced anti-tumour effects of acriflavine in combination with guanosine in mice | Q73120951 |
| | Ca2+-dependent kainate excitotoxicity in the chick embryonic neural retina ex vivo | Q73298476 |
| | Apoptosis induced by nucleosides in the human hepatoma HepG2. | Q40357424 |
| | Guanosine protects SH-SY5Y cells against beta-amyloid-induced apoptosis | Q40568471 |
| | Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade | Q40722338 |
| | Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP. | Q40722484 |
| | Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor | Q41064388 |
| | Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells | Q41095944 |
| | Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system | Q41205766 |
| | Extracellular metabolism of nucleotides in the nervous system | Q41456052 |
| | Current perspectives on the antidepressant-like effects of guanosine. | Q41647786 |
| | Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport | Q41818231 |
| | Specific [(3)H]-guanosine binding sites in rat brain membranes | Q42021948 |
| | Guanosine prevents nitroxidative stress and recovers mitochondrial membrane potential disruption in hippocampal slices subjected to oxygen/glucose deprivation. | Q42363254 |
| | Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder. | Q42372900 |
| | Vital role of protein kinase C-related kinase in the formation and stability of neurites during hypoxia. | Q42391322 |
| | The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. | Q42460494 |
| | Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine | Q42464887 |
| | Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia | Q42466571 |
| | Guanine nucleotide modulation of [3H]TCP binding to the NMDA receptor complex | Q42479389 |
| | Systemic administration of GMP induces anxiolytic-like behavior in rats. | Q43010610 |
| | Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model | Q43233582 |
| | Interference of propylene glycol with the hole-board test. | Q43564176 |
| | Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells. | Q43640727 |
| | Effect of orally administered guanosine on seizures and death induced by glutamatergic agents. | Q43726002 |
| | Guanine based purines inhibit [(3)H]glutamate and [(3)H]AMPA binding at postsynaptic densities from cerebral cortex of rats | Q43885970 |
| | The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action | Q44241429 |
| | Chronically administered guanosine is anticonvulsant, amnesic and anxiolytic in mice | Q44466849 |
| | Guanosine enhances NGF-stimulated neurite outgrowth in PC12 cells | Q44620410 |
| | Guanosine promotes myelination and functional recovery in chronic spinal injury | Q44685181 |
| | Guanine derivatives modulate L-glutamate uptake into rat brain synaptic vesicles. | Q44700772 |
| | Anticonvulsant effect of GMP depends on its conversion to guanosine. | Q44814268 |
| | Characterization of imido [8-(3)H] guanosine 5'-triphosphate binding sites to rat brain membranes. | Q44852281 |
| | Effects of chronic administered guanosine on behavioral parameters and brain glutamate uptake in rats. | Q45159502 |
| | Guanosine behind the scene. | Q45167440 |
| | Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion. | Q45325730 |
| | Guanosine-5'-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition. | Q45940792 |
| | Importance of schedule of administration in the therapeutic efficacy of guanosine: early intervention after injury enhances glutamate uptake in model of hypoxia-ischemia. | Q46322199 |
| | Guanosine improves motor behavior, reduces apoptosis, and stimulates neurogenesis in rats with parkinsonism. | Q46347416 |
| | Intracerebroventricular guanine-based purines protect against seizures induced by quinolinic acid in mice | Q46366822 |
| | Antinociceptive effects of intracerebroventricular administration of guanine-based purines in mice: evidences for the mechanism of action | Q46426065 |
| | Hypoxic-ischemic insult decreases glutamate uptake by hippocampal slices from neonatal rats: prevention by guanosine. | Q46624043 |
| | In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine. | Q46631297 |
| | Guanosine Protects Against Cortical Focal Ischemia. Involvement of Inflammatory Response. | Q46814683 |
| | GTP uptake into rat brain synaptic vesicles | Q46889036 |
| | Neuroprotective effects of guanosine administration on behavioral, brain activity, neurochemical and redox parameters in a rat model of chronic hepatic encephalopathy. | Q46899015 |
| | Mechanisms involved in the antinociception induced by spinal administration of inosine or guanine in mice | Q47610315 |
| | Protective effects of guanosine against sepsis-induced damage in rat brain and cognitive impairment | Q47911475 |
| | Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways. | Q47978385 |
| | Chick kainate binding protein lacks GTPase activity | Q48103454 |
| | Absence epileptic activity changing effects of non-adenosine nucleoside inosine, guanosine and uridine in Wistar Albino Glaxo Rijswijk rats | Q48147817 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 376 | |
| P577 | publication date | 2018-10-23 | |
| P1433 | published in | Frontiers in Cellular Neuroscience | Q2131509 |
| P1476 | title | Neuromodulatory Effects of Guanine-Based Purines in Health and Disease | |
| P478 | volume | 12 | |