Cholera toxin B subunit promotes the induction of regulatory T cells by preventing human dendritic cell maturation

scientific article

Cholera toxin B subunit promotes the induction of regulatory T cells by preventing human dendritic cell maturation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1189/JLB.1207850
P698PubMed publication ID18562485
P5875ResearchGate publication ID5293188

P2093author name stringMonica Boirivant
Manuela Colucci
Antonella D'Ambrosio
Francesca Quintieri
Orsola Pugliese
P2860cites workRecombinant cholera toxin B subunit activates dendritic cells and enhances antitumor immunity.Q40467105
Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric floraQ40688436
Cholera toxin B pretreatment of macrophages and monocytes diminishes their proinflammatory responsiveness to lipopolysaccharideQ40753141
Vasoactive intestinal peptide generates human tolerogenic dendritic cells that induce CD4 and CD8 regulatory T cells.Q41888326
Cholera toxin subunit B inhibits IL-12 and IFN-{gamma} production and signaling in experimental colitis and Crohn's disease.Q41998304
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cellsQ42944333
Oral administration of collagen conjugated with cholera toxin induces tolerance to type II collagen and suppresses chondritis in an animal model of autoimmune ear diseaseQ43683297
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cellsQ45878833
Elevated T regulatory cells in long-term stable transplant tolerance in rhesus macaques induced by anti-CD3 immunotoxin and deoxyspergualinQ46844016
The cholera toxin B subunit is a mucosal adjuvant for oral tolerance induction in type 1 diabetesQ47904800
Induction of mucosal and systemic immune responses by intranasal immunization using recombinant cholera toxin B subunit as an adjuvant.Q48026780
Recombinant cholera toxin B subunit acts as an adjuvant for the mucosal and systemic responses of mice to mucosally co-administered bovine serum albuminQ48026935
Production of IL-10 by alloreactive sibling donor cells and its influence on the development of acute GVHD.Q50749410
Interleukin-10-mediated regulatory T-cell responses to epitopes on a human red blood cell autoantigen.Q52944948
Reduced expression of the regulatory CD4+ T cell subset is related to Th1/Th2 balance and disease severity in rheumatoid arthritis.Q55033737
Relation of an Interleukin-10 Promoter Polymorphism to Graft-versus-Host Disease and Survival after Hematopoietic-Cell TransplantationQ58814550
The induction of tolerance by dendritic cells that have captured apoptotic cellsQ24671078
Dendritic cells and the control of immunityQ27860918
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaQ28251443
Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responsesQ28369396
Immunobiology of dendritic cellsQ29547465
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitisQ29619339
A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergenQ30433007
Oral administration of recombinant cholera toxin subunit B inhibits IL-12-mediated murine experimental (trinitrobenzene sulfonic acid) colitisQ32024894
Dendritic cells as key targets for immunomodulation by Vitamin D receptor ligandsQ33204344
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cellsQ34318928
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.Q34569888
Functional modulation of dendritic cells to suppress adaptive immune responsesQ35093120
Human allograft acceptance is associated with immune regulationQ35128097
IL-10-producing T cells suppress immune responses in anergic tuberculosis patientsQ35159232
Dendritic-cell control of pathogen-driven T-cell polarizationQ35597117
Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agentQ35619878
IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damageQ35951526
Different faces of regulatory DCs in homeostasis and immunityQ36061016
A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetesQ36140954
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.Q36370315
Tr1 cells: from discovery to their clinical application.Q36390028
Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunitQ37494112
Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cellsQ39522002
Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 developmentQ39741614
Gliadin-specific type 1 regulatory T cells from the intestinal mucosa of treated celiac patients inhibit pathogenic T cellsQ40236078
P433issue3
P921main subjectdendritic cellQ506253
choleraQ12090
P304page(s)661-668
P577publication date2008-06-18
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleCholera toxin B subunit promotes the induction of regulatory T cells by preventing human dendritic cell maturation
P478volume84

Reverse relations

cites work (P2860)
Q35155875AB toxins: a paradigm switch from deadly to desirable
Q26782576Cholera Toxin Subunit B as Adjuvant--An Accelerator in Protective Immunity and a Break in Autoimmunity
Q36551840Cholera toxin B subunit linked to glutamic acid decarboxylase suppresses dendritic cell maturation and function.
Q37954306Cholera-like enterotoxins and Regulatory T cells
Q37530535DNA and protein co-administration induces tolerogenic dendritic cells through DC-SIGN mediated negative signals
Q33820591Enhanced antigen uptake by dendritic cells induced by the B pentamer of the type II heat-labile enterotoxin LT-IIa requires engagement of TLR2.
Q34631825How tolerogenic dendritic cells induce regulatory T cells
Q84401327Prolonged survival time of allografts by the oral administration of RDP58 linked to the cholera toxin B subunit
Q34629092Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit.
Q27687098Targeting dendritic cell function during systemic autoimmunity to restore tolerance
Q57490842The Nontoxic Cholera B Subunit Is a Potent Adjuvant for Intradermal DC-Targeted Vaccination
Q26785900The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity
Q34422017The role of dendritic cells in tissue-specific autoimmunity.
Q47105986Therapeutic Potential of Cholera Toxin B Subunit for the Treatment of Inflammatory Diseases of the Mucosa
Q35138715Vibrio cholerae O1 infection induces proinflammatory CD4+ T-cell responses in blood and intestinal mucosa of infected humans

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