The role of PGP9.5 as a tumor suppressor gene in human cancer

scientific article

The role of PGP9.5 as a tumor suppressor gene in human cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/IJC.23354
P932PMC publication ID3069849
P698PubMed publication ID18512240
P5875ResearchGate publication ID5339201

P50authorDavid SidranskyQ106888457
P2093author name stringMasaki Mori
Keishi Yamashita
Myoung Sook Kim
Motonobu Osada
Hannah L Park
Yutaka Tokumaru
P2860cites workSerial analysis of gene expression in non-small cell lung cancerQ77726399
PGP9.5 overexpression in esophageal squamous cell carcinomaQ79192990
Anti-angiogenic activity of torilin, a sesquiterpene compound isolated fromTorilis japonicaQ104666991
Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivoQ28585083
The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolaseQ28941761
Gene silencing in cancer in association with promoter hypermethylationQ29617274
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibilityQ34157005
PGP9.5 as a candidate tumor marker for non-small-cell lung cancerQ35787842
AIS is an oncogene amplified in squamous cell carcinomaQ36978000
Anti-angiogenic activity of torilin, a sesquiterpene compound isolated from Torilis japonicaQ38526276
p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomasQ39742724
PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinomaQ40414420
Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.Q40432782
Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cellsQ40502949
Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencingQ40519902
Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer.Q40730697
Methylation status in the promoter region of the human PGP9.5 gene in cancer and normal tissuesQ40793222
Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.Q42163115
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.Q44259986
PGP9.5 as a prognostic factor in pancreatic cancerQ73393183
PGP9.5 as a marker for invasive colorectal cancerQ77522166
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)753-759
P577publication date2008-08-01
P1433published inInternational Journal of CancerQ332492
P1476titleThe role of PGP9.5 as a tumor suppressor gene in human cancer
P478volume123

Reverse relations

cites work (P2860)
Q34708747A combination of two electrophoretical approaches for detailed proteome-based characterization of SCLC subtypes
Q34200303A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma
Q35004607Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.
Q36027109Automated PGP9.5 immunofluorescence staining: a valuable tool in the assessment of small fiber neuropathy?
Q37703387Bronchial airway gene expression in smokers with lung or head and neck cancer
Q36715039Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.
Q33920324Cancer immunoediting from immunosurveillance to tumor escape in microvillus-formed niche: a study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer
Q38123912Clinical neuropathology practice guide 5-2013: markers of neuronal maturation
Q34058385Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma.
Q36300261DNA promoter methylation as a diagnostic and therapeutic biomarker in gallbladder cancer
Q36136842Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype
Q39533559Frequent CpG methylation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in sporadic and hereditary Tunisian breast cancer patients: clinical significance
Q37824622Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications
Q30317812Heterogeneous expression and functional relevance of the ubiquitin carboxyl-terminal hydrolase L1 in melanoma
Q38250190Immunocytochemical markers of neuronal maturation in human diagnostic neuropathology
Q39611471NF-κB signaling inhibits ubiquitin carboxyl-terminal hydrolase L1 gene expression
Q87363127Parafibromin, galectin-3, PGP9.5, Ki67, and cyclin D1: using an immunohistochemical panel to aid in the diagnosis of parathyroid cancer
Q38565170Potential prognostic marker ubiquitin carboxyl-terminal hydrolase-L1 does not predict patient survival in non-small cell lung carcinoma
Q39727817Potential utility of HOP homeobox gene promoter methylation as a marker of tumor aggressiveness in gastric cancer
Q43570380Prognostic relevance of ubiquitin C-terminal hydrolase L1 (UCH-L1) mRNA and protein expression in breast cancer patients
Q57105884Prostate cancer tissues with positive TMPRSS2-ERG-gene-fusion status may display enhanced nerve density
Q38071897Review of the alterations in DNA methylation in esophageal squamous cell carcinoma
Q38019157Role of DNA methylation in head and neck cancer
Q36221083The diagnosis value of promoter methylation of UCHL1 in the serum for progression of gastric cancer
Q89638568UCH-L1-mediated Down-regulation of Estrogen Receptor α Contributes to Insensitivity to Endocrine Therapy for Breast Cancer
Q36464299UCH-LI acts as a novel prognostic biomarker in gastric cardiac adenocarcinoma
Q64063558UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells
Q34228778Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions
Q33799710Ubiquitin C-terminal hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation
Q85843041Ubiquitin carboxy-terminal hydrolase L1 may be involved in the development of mammary phyllodes tumors
Q39019302Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation
Q47592158Ubiquitin carboxyl-terminal hydrolases: involvement in cancer progression and clinical implications
Q37481100Unique DNA methylation loci distinguish anatomic site and HPV status in head and neck squamous cell carcinoma