Glycogen synthase kinase-3beta inhibition preserves hematopoietic stem cell activity and inhibits leukemic cell growth

scientific article

Glycogen synthase kinase-3beta inhibition preserves hematopoietic stem cell activity and inhibits leukemic cell growth is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1634/STEMCELLS.2007-0600
P698PubMed publication ID18323411
P5875ResearchGate publication ID5529765

P2093author name stringRobert Knight
Alla Dolnikov
Geoff Symonds
Sylvie Shen
Robert Lindeman
Emma Song
Tracey A O'Brien
Tiffany Holmes
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
cell growthQ189159
P304page(s)1288-1297
P577publication date2008-03-06
P1433published inStem CellsQ15724411
P1476titleGlycogen synthase kinase-3beta inhibition preserves hematopoietic stem cell activity and inhibits leukemic cell growth
P478volume26

Reverse relations

cites work (P2860)
Q37075360A Novel Glycogen Synthase Kinase-3 Inhibitor Optimized for Acute Myeloid Leukemia Differentiation Activity
Q33655531Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer
Q51839740Direct GSK-3β Inhibition Enhances Mesenchymal Stromal Cell Migration by Increasing Expression of Beta-PIX and CXCR4
Q28553790Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells
Q39639021Ex vivo expansion of cord blood progenitors impairs their short-term and long-term repopulating activity associated with transcriptional dysregulation of signalling networks.
Q41461266GSK-3 Inhibition Sensitizes Acute Myeloid Leukemia Cells to 1,25D-Mediated Differentiation
Q54378200GSK-3β inhibition promotes early engraftment of ex vivo-expanded haematopoietic stem cells
Q54640874GSK-3β inhibition promotes engraftment of ex vivo-expanded hematopoietic stem cells and modulates gene expression
Q54482072GSK3 inhibition prevents lethal GVHD in mice
Q34119834GSK3 is a regulator of RAR-mediated differentiation
Q38394964GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb
Q39498749GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement
Q42140104Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML.
Q39606660Genome-wide screen reveals WNT11, a non-canonical WNT gene, as a direct target of ETS transcription factor ERG
Q39426971Glycogen synthase kinase-3 (GSK-3) inhibition induces apoptosis in leukemic cells through mitochondria-dependent pathway
Q41167448Glycogen synthase kinase-3β inhibition induces nuclear factor-κB-mediated apoptosis in pediatric acute lymphocyte leukemia cells
Q38035450Hematopoietic stem cell expansion: challenges and opportunities.
Q35979303Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells
Q35963342Inhibitor of PI3K/Akt Signaling Pathway Small Molecule Promotes Motor Neuron Differentiation of Human Endometrial Stem Cells Cultured on Electrospun Biocomposite Polycaprolactone/Collagen Scaffolds.
Q36457006Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways
Q37188090Modeling the Pro-inflammatory Tumor Microenvironment in Acute Lymphoblastic Leukemia Predicts a Breakdown of Hematopoietic-Mesenchymal Communication Networks
Q90642732Phase I Trial of Lithium and Tretinoin for Treatment of Relapsed and Refractory Non-promyelocytic Acute Myeloid Leukemia
Q37452373Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice.
Q36768725Repression of GSK3 restores NK cell cytotoxicity in AML patients
Q41723841Retinoid differentiation therapy for common types of acute myeloid leukemia
Q36729132Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer
Q38004725Selective treatment of mixed-lineage leukemia leukemic stem cells through targeting glycogen synthase kinase 3 and the canonical Wnt/β-catenin pathway
Q51442692Sex differences in the GSK3β-mediated survival of adherent leukemic progenitors
Q54542811Small molecule induction of neural‐like cells from bone marrow‐mesenchymal stem cells
Q36089825The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation
Q54982375The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells.
Q38155205Wnt signaling in leukemias and myeloma: T-cell factors are in control
Q34286624Wnt-related molecules and signaling pathway equilibrium in hematopoiesis

Search more.