| scholarly article | Q13442814 |
| P2093 | author name string | Allan Balmain | |
| Byron Hann | |||
| P2860 | cites work | The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53 | Q24679341 |
| Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations | Q27730815 | ||
| p53, the cellular gatekeeper for growth and division | Q27860990 | ||
| A common polymorphism acts as an intragenic modifier of mutant p53 behaviour | Q28118809 | ||
| The INK4a/ARF network in tumour suppression | Q28190064 | ||
| Mutations in the p53 gene occur in diverse human tumour types | Q28249770 | ||
| Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line | Q29547239 | ||
| p53-dependent cell cycle control: response to genotoxic stress | Q33547812 | ||
| The p53 pathway | Q33643359 | ||
| p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection | Q33785919 | ||
| p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication | Q33814900 | ||
| a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer | Q33912833 | ||
| Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. | Q33927095 | ||
| p53: death star | Q34103258 | ||
| p53 in signaling checkpoint arrest or apoptosis | Q34395659 | ||
| An adenovirus mutant that replicates selectively in p53-deficient human tumor cells | Q34399844 | ||
| Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection | Q34562704 | ||
| Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation | Q34587260 | ||
| High metastatic potential in mice inheriting a targeted p53 missense mutation | Q35673678 | ||
| The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle | Q35875344 | ||
| An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control | Q36065506 | ||
| Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains | Q36820883 | ||
| A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain | Q39458140 | ||
| The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 status | Q39551790 | ||
| Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells. | Q39582723 | ||
| p73 function is inhibited by tumor-derived p53 mutants in mammalian cells. | Q39610993 | ||
| Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis | Q40694250 | ||
| How loops, beta sheets, and alpha helices help us to understand p53. | Q40694267 | ||
| Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis | Q40811131 | ||
| Oncolytic potential of E1B 55 kDa-deleted YKL-1 recombinant adenovirus: correlation with p53 functional status | Q40845651 | ||
| Activation of heat-shock response by an adenovirus is essential for virus replication. | Q40853100 | ||
| Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light | Q40922670 | ||
| Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and DeltaE1B adenovirus replication in human cells | Q40928320 | ||
| p53-dependent cell death/apoptosis is required for a productive adenovirus infection | Q41009439 | ||
| Expression and stability of p53 protein in normal human mammary epithelial cells | Q41554910 | ||
| Gain of function mutations in p53. | Q41557652 | ||
| Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells | Q41731114 | ||
| Cell cycle response to DNA damage differs in bronchial epithelial cells and lung fibroblasts. | Q42442089 | ||
| Transcriptional repression by the C-terminal domain of p53. | Q42489378 | ||
| Induction of gene amplification as a gain-of-function phenotype of mutant p53 proteins | Q44010460 | ||
| Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). | Q45180301 | ||
| Cellular adhesion regulates p53 protein levels in primary human keratinocytes. | Q45957895 | ||
| Androgen-independent growth of LNCaP prostate cancer cells is mediated by gain-of-function mutant p53 | Q46003031 | ||
| Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents | Q46061653 | ||
| ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents | Q46343726 | ||
| Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene. | Q53551443 | ||
| ONYX-015: clinical data are encouraging | Q56898602 | ||
| Overproduction of p53 antigen makes established cells highly tumorigenic | Q59053537 | ||
| Isolation of type 5 adenovirus mutants with a cold-sensitive host range phenotype: genetic evidence of an adenovirus transformation maintenance function | Q64381170 | ||
| Attenuated response of p53 and p21 in primary cultures of human prostatic epithelial cells exposed to DNA-damaging agents | Q71705720 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Adenoviridae | Q193447 |
| P304 | page(s) | 11588-11595 | |
| P577 | publication date | 2003-11-01 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants | |
| P478 | volume | 77 |
| Q38797735 | A modified p53 enhances apoptosis in sarcoma cell lines mediated by doxorubicin |
| Q33299767 | A new therapy for highly effective tumor eradication using HVJ-E combined with chemotherapy |
| Q37409025 | Adenoviral vector-based strategies for cancer therapy |
| Q34301861 | Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblasts |
| Q35488742 | Adenovirus replaces mitotic checkpoint controls |
| Q39960855 | An early function of the adenoviral E1B 55 kDa protein is required for the nuclear relocalization of the cellular p53 protein in adenovirus-infected normal human cells |
| Q33868732 | Antitumor activity of an hTERT promoter-regulated tumor-selective oncolytic adenovirus in human hepatocellular carcinoma |
| Q36519055 | Cancer gene therapy: combination with radiation therapy and the role of bystander cell killing in the anti-tumor effect |
| Q40541104 | E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection |
| Q39912230 | E2F promoter-regulated oncolytic adenovirus with p16 gene induces cell apoptosis and exerts antitumor effect on gastric cancer |
| Q35118933 | Gene therapy and targeted toxins for glioma |
| Q57006162 | Gene therapy and targeted toxins for glioma |
| Q44068008 | IPS-1 plays a dual function to directly induce apoptosis in murine melanoma cells by inactivated Sendai virus |
| Q38842126 | Oncolytic virotherapy for urological cancers |
| Q36710840 | Restoration of wild-type p53 function in human cancer: relevance for tumor therapy. |
| Q35986418 | The tumor suppressor gene TP53: implications for cancer management and therapy |
| Q45865848 | Treatment of patient tumor-derived colon cancer xenografts by a TRAIL gene-armed oncolytic adenovirus |
| Q36318145 | Viruses - seeking and destroying the tumor program |
| Q40358341 | p53 promotes adenoviral replication and increases late viral gene expression |
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