scholarly article | Q13442814 |
P50 | author | Richard Flavell | Q2149481 |
Mercedes Rincón | Q97069657 | ||
P2860 | cites work | NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus | Q24316786 |
Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins | Q24317724 | ||
Characterization of antigen receptor response elements within the interleukin-2 enhancer | Q24632042 | ||
Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding | Q24678802 | ||
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells | Q27860599 | ||
NF-AT components define a family of transcription factors targeted in T-cell activation | Q28114991 | ||
The role of the CD28 receptor during T cell responses to antigen | Q28263234 | ||
The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun | Q28263918 | ||
B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells | Q28279870 | ||
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor | Q28288345 | ||
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements | Q28288355 | ||
Isolation of the cyclosporin-sensitive T cell transcription factor NFATp | Q28511815 | ||
NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity | Q28591436 | ||
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties | Q29547848 | ||
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages | Q29618421 | ||
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation | Q29620223 | ||
The mechanism of action of cyclosporin A and FK506 | Q30014847 | ||
Identification of a putative regulator of early T cell activation genes | Q34171263 | ||
Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation | Q34591923 | ||
Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo | Q36353340 | ||
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells | Q36353430 | ||
Transcription of the interleukin 4 gene is regulated by multiple promoter elements | Q36361828 | ||
Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells | Q36362494 | ||
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse | Q36364541 | ||
Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells | Q36365491 | ||
Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells | Q36557490 | ||
Molecular dissection of the mouse interleukin-4 promoter | Q36607974 | ||
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming | Q36638672 | ||
B70 antigen is a second ligand for CTLA-4 and CD28 | Q36697598 | ||
A common factor regulates both Th1- and Th2-specific cytokine gene expression | Q37628403 | ||
AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. | Q37636349 | ||
Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene | Q38295828 | ||
Cyclosporin-A sensitive induction of NF-AT in murine B cells | Q38307826 | ||
Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc | Q38317270 | ||
Comparative analysis of NFAT (nuclear factor of activated T cells) complex in human T and B lymphocytes. | Q38317669 | ||
The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. | Q38321239 | ||
Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex. | Q38321848 | ||
Molecular basis for developmental changes in interleukin-2 gene inducibility | Q38322912 | ||
Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation | Q38342696 | ||
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice | Q38359933 | ||
Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy | Q38624477 | ||
Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter | Q40412449 | ||
Lymphocyte responses and cytokines | Q40620203 | ||
Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB | Q40677556 | ||
NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes | Q40693171 | ||
Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes | Q40817161 | ||
An enhanced immune response in mice lacking the transcription factor NFAT1. | Q41199166 | ||
Functional role and signal-induced modulation of proteins recognizing the conserved TCATTT-containing promoter elements in the murine IL-5 and GM-CSF genes in T lymphocytes. | Q41435530 | ||
JNK is involved in signal integration during costimulation of T lymphocytes. | Q41461688 | ||
Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4. | Q41465837 | ||
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin | Q41618754 | ||
Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor | Q41721375 | ||
Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo | Q41761641 | ||
Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production | Q41853080 | ||
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy | Q42675165 | ||
Effect of liposomal model membrane composition on immunogenicity | Q44507627 | ||
Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor | Q46155874 | ||
Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. | Q46195210 | ||
IL-4 directs the development of Th2-like helper effectors | Q46390956 | ||
Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells | Q46681487 | ||
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A | Q46979889 | ||
Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major. | Q54265963 | ||
Nuclear factor of activated T cells contains Fos and Jun. | Q54271859 | ||
Human T cell activation through the activation-inducer molecule/CD69 enhances the activity of transcription factor AP-1 | Q58064746 | ||
Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene | Q59084755 | ||
The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells | Q63363245 | ||
Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element | Q72169111 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1522-1534 | |
P577 | publication date | 1997-03-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells | |
P478 | volume | 17 |
Q77328536 | A novel role for the major histocompatibility complex class II transactivator CIITA in the repression of IL-4 production |
Q44158836 | A virtual culture of CD4+ T lymphocytes |
Q35758681 | Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells |
Q56907146 | CTLA4 ligation attenuates AP-1, NFAT and NF-kappaB activity in activated T cells |
Q36311595 | Carcinogenic effect of nickel compounds |
Q24806926 | Cell fate decision: T-helper 1 and 2 subsets in immune responses |
Q35131697 | Cell signaling and transcription factor activation by asbestos in lung injury and disease |
Q73998192 | Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo |
Q73674688 | Characterization of a novel negative regulatory element in the human interleukin 4 promoter |
Q27930272 | Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR |
Q34467702 | Control of T helper cell differentiation--in search of master genes |
Q40261258 | Cyclooxygenase-2 induction by arsenite is through a nuclear factor of activated T-cell-dependent pathway and plays an antiapoptotic role in Beas-2B cells |
Q41732572 | Cytokines induce the development of functionally heterogeneous T helper cell subsets |
Q40077717 | Deferoxamine synergistically enhances iron-mediated AP-1 activation: a showcase of the interplay between extracellular-signal-regulated kinase and tyrosine phosphatase |
Q42047867 | Development of colitis in signal transducers and activators of transcription 6-deficient T-cell receptor alpha-deficient mice: a potential role of signal transducers and activators of transcription 6-independent interleukin-4 signaling for the gener |
Q74045622 | Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1 |
Q23919673 | Essential role of ROS-mediated NFAT activation in TNF-alpha induction by crystalline silica exposure |
Q81082199 | Expression of human pim family genes is selectively up-regulated by cytokines promoting T helper type 1, but not T helper type 2, cell differentiation |
Q34341389 | Gammadelta T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand |
Q92055113 | Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer's disease |
Q33632431 | Helper T cell differentiation |
Q31929678 | IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production. |
Q36371096 | Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation |
Q37118993 | Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo |
Q33888844 | Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway |
Q23914968 | Involvement of hydrogen peroxide in asbestos-induced NFAT activation |
Q37120843 | Involvement of nuclear factor of activated T cells activation in UV response. Evidence from cell culture and transgenic mice. |
Q34437100 | Lead induces COX-2 expression in glial cells in a NFAT-dependent, AP-1/NFκB-independent manner |
Q37173306 | Mechanisms in allergic airway inflammation - lessons from studies in the mouse |
Q33607430 | Molecular regulation of cytokine gene expression during the immune response |
Q73533450 | NF-ATp plays a prominent role in the transcriptional induction of Th2-type lymphokines |
Q40276663 | NFAT3 is required for EGF-induced COX-2 transcription, but neither iNOS transcription nor cell transformation in Cl 41 cells |
Q26824937 | Nuclear factor of activated T cells - a transcription factor family as critical regulator in lung and colon cancer |
Q40321353 | Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3. |
Q30437023 | RSK2 mediates muscle cell differentiation through regulation of NFAT3. |
Q24533533 | Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation |
Q34567533 | Regulation of allergic airways inflammation by cytokines and glucocorticoids |
Q33939862 | Reprogramming transcription during the differentiation of precursor CD4+ T cells into effector Th1 and Th2 cells |
Q38334052 | Retarded thymic involution and massive germinal center formation in NF-ATp-deficient mice |
Q40845202 | Role of Tec kinase in nuclear factor of activated T cells signaling |
Q24719493 | Role of bioavailable iron in coal dust-induced activation of activator protein-1 and nuclear factor of activated T cells: difference between Pennsylvania and Utah coal dusts |
Q27303152 | Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease |
Q52597722 | Salp15, an ixodes scapularis salivary protein, inhibits CD4(+) T cell activation. |
Q35951832 | Signaling pathways in Th2 development |
Q34450447 | Suppressed RNA-polymerase 1 pathway is associated with benign multiple sclerosis |
Q74591322 | T lymphocyte differentiation in the periphery |
Q41651076 | T-cell subsets: transcriptional control in the Th1/Th2 decision |
Q37459250 | The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival |
Q28145665 | The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways |
Q37061850 | The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells |
Q33736008 | The molecular basis of T cell differentiation |
Q28252683 | The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway |
Q29614226 | The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells |
Q41065666 | The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production |
Q35090249 | Transcriptional control of rapid recall by memory CD4 T cells |
Q39490292 | Transcriptional repressor DREAM regulates T-lymphocyte proliferation and cytokine gene expression. |
Q24293007 | Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization |
Q23911186 | Vanadium-induced nuclear factor of activated T cells activation through hydrogen peroxide |
Q33968015 | Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter |
Q40786707 | Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN-gamma production |
Q46177075 | Zinc and the cytoskeleton in the neuronal modulation of transcription factor NFAT. |
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