| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S1286-4579(99)80013-6 |
| P698 | PubMed publication ID | 10847765 |
| P2093 | author name string | R A Flavell | |
| M Rincón | |||
| P2860 | cites work | ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF | Q24304344 |
| JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 | ||
| Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase | Q24309889 | ||
| A protein kinase involved in the regulation of inflammatory cytokine biosynthesis | Q24311139 | ||
| Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms | Q24312029 | ||
| NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus | Q24316786 | ||
| Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins | Q24317724 | ||
| A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3 | Q24320233 | ||
| MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates | Q24322852 | ||
| Characterization of the structure and function of a novel MAP kinase kinase (MKK6) | Q24336966 | ||
| Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2 | Q24532154 | ||
| MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway | Q24650627 | ||
| NF-AT components define a family of transcription factors targeted in T-cell activation | Q28114991 | ||
| Transcription factors of the NFAT family: regulation and function | Q28237645 | ||
| A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells | Q28237789 | ||
| The role of the CD28 receptor during T cell responses to antigen | Q28263234 | ||
| The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun | Q28263918 | ||
| Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development | Q28268881 | ||
| A calcineurin-dependent transcriptional pathway for cardiac hypertrophy | Q28269300 | ||
| Essential role of Stat6 in IL-4 signalling | Q28276199 | ||
| Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene | Q28276209 | ||
| Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase | Q28280649 | ||
| Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine | Q28287650 | ||
| Isolation of the cyclosporin-sensitive T cell transcription factor NFATp | Q28511815 | ||
| NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity | Q28591436 | ||
| Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis | Q29547567 | ||
| The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells | Q29614226 | ||
| A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins | Q29617438 | ||
| Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages | Q29618421 | ||
| The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
| Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation | Q29620223 | ||
| Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors | Q30452676 | ||
| Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway | Q33888844 | ||
| Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27. | Q34323179 | ||
| Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells | Q34388169 | ||
| Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation | Q34419537 | ||
| Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation | Q34591923 | ||
| Identifying differences in mRNA expression by representational difference analysis of cDNA | Q35004368 | ||
| Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells | Q36353430 | ||
| Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells | Q36362494 | ||
| Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse | Q36364541 | ||
| Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells | Q36365491 | ||
| Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells | Q36376543 | ||
| Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming | Q36638672 | ||
| B70 antigen is a second ligand for CTLA-4 and CD28 | Q36697598 | ||
| The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. | Q36804149 | ||
| AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. | Q37636349 | ||
| Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene | Q38295828 | ||
| The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. | Q38321239 | ||
| Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation | Q38342696 | ||
| Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice | Q38359933 | ||
| Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy | Q38624477 | ||
| Differential transcription directed by discrete gamma interferon promoter elements in naive and memory (effector) CD4 T cells and CD8 T cells | Q40020684 | ||
| Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells | Q40021175 | ||
| Lifespan of lymphocytes | Q40414738 | ||
| T-Cell Subsets: Who does the polarizing? | Q40427874 | ||
| Lymphocyte responses and cytokines | Q40620203 | ||
| Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors | Q40715828 | ||
| Lifespans of naive, memory and effector lymphocytes | Q40832453 | ||
| The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production | Q41065666 | ||
| Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene | Q41093086 | ||
| Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice | Q41185362 | ||
| An enhanced immune response in mice lacking the transcription factor NFAT1. | Q41199166 | ||
| Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun | Q41343659 | ||
| JNK is involved in signal integration during costimulation of T lymphocytes. | Q41461688 | ||
| FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin | Q41618754 | ||
| T-cell subsets: transcriptional control in the Th1/Th2 decision | Q41651076 | ||
| An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control | Q41728250 | ||
| Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo | Q41761641 | ||
| Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production | Q41853080 | ||
| B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy | Q42675165 | ||
| IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. | Q45933733 | ||
| Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A | Q46979889 | ||
| Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells | Q47781913 | ||
| Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major. | Q54265963 | ||
| Nuclear factor of activated T cells contains Fos and Jun. | Q54271859 | ||
| The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells | Q58010506 | ||
| Effect of inhibitors of eicosanoid metabolism in murine collagen-induced arthritis | Q70411071 | ||
| Pyridinyl imidazoles inhibit the inflammatory phase of delayed type hypersensitivity reactions without affecting T-dependent immune responses | Q72512112 | ||
| Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway | Q73025247 | ||
| Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1 | Q74045622 | ||
| Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc | Q74171908 | ||
| P433 | issue | 1 | |
| P1104 | number of pages | 8 | |
| P304 | page(s) | 43-50 | |
| P577 | publication date | 1999-01-01 | |
| P1433 | published in | Microbes and Infection | Q15760242 |
| P1476 | title | Reprogramming transcription during the differentiation of precursor CD4+ T cells into effector Th1 and Th2 cells | |
| P478 | volume | 1 |
| Q78492717 | Interleukin-6 promotes the production of interleukin-4 and interleukin-5 by interleukin-2-dependent and -independent mechanisms in freshly isolated human T cells |
| Q36228304 | Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin |
| Q77813238 | Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling |
| Q37580266 | Neither T-helper type 2 nor Foxp3+ regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity |
| Q36229701 | Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity |
| Q45772626 | Pitavastatin regulates helper T-cell differentiation and ameliorates autoimmune myocarditis in mice. |
| Q40786707 | Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN-gamma production |
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