scholarly article | Q13442814 |
P2093 | author name string | D H Spector | |
M H Sommer | |||
A L Scully | |||
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A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle | Q24319785 | ||
The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB | Q24563487 | ||
Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase | Q28131695 | ||
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Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations | Q29620211 | ||
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product | Q29620421 | ||
Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins | Q34352327 | ||
Cyclin A and the retinoblastoma gene product complex with a common transcription factor | Q34756189 | ||
An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter | Q36069170 | ||
TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein | Q36535897 | ||
Stimulation of cellular DNA synthesis by human cytomegalovirus | Q36556598 | ||
Human cytomegalovirus immediate-early gene 2 protein interacts with itself and with several novel cellular proteins | Q36651434 | ||
Identification and mapping of dimerization and DNA-binding domains in the C terminus of the IE2 regulatory protein of human cytomegalovirus | Q36653844 | ||
The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signal | Q36701599 | ||
Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element. | Q36781988 | ||
Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins | Q36803147 | ||
Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains | Q36803353 | ||
Human cytomegalovirus immediate-early two protein region involved in negative regulation of the major immediate-early promoter | Q36811230 | ||
Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1. | Q36853873 | ||
trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus | Q36865895 | ||
Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene. | Q36872629 | ||
Structural analysis of the major immediate early gene of human cytomegalovirus | Q36911017 | ||
Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID | Q37531197 | ||
Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein | Q38319003 | ||
E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection | Q38325725 | ||
A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein | Q38340347 | ||
Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation | Q38347799 | ||
The 86-kilodalton IE-2 protein of human cytomegalovirus is a sequence-specific DNA-binding protein that interacts directly with the negative autoregulatory response element located near the cap site of the IE-1/2 enhancer-promoter. | Q40043548 | ||
Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain | Q40048677 | ||
The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID. | Q40066427 | ||
In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins. | Q41576192 | ||
Transcription in human fibroblasts permissively infected by human cytomegalovirus strain AD169. | Q43820771 | ||
The Drosophila glutathione S-transferase 1-1 is encoded by an intronless gene at 87B. | Q43988476 | ||
Characterization of a variant rat glutathione S-transferase by cDNA expression in Escherichia coli | Q45164448 | ||
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor | Q46050449 | ||
Binding of general transcription factor TFIIB to an acidic activating region | Q59058683 | ||
Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID | Q59070657 | ||
The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio | Q72696029 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Cytomegalovirus | Q6946 |
retinoblastoma | Q500695 | ||
P304 | page(s) | 6223-6231 | |
P577 | publication date | 1994-10-01 | |
P1433 | published in | Journal of Virology | Q1251128 |
P1476 | title | Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein | |
P478 | volume | 68 |
Q33603447 | Activation of transcription of the human cytomegalovirus early UL4 promoter by the Ets transcription factor binding element |
Q34485281 | Alternative Splicing of the Human Cytomegalovirus Major Immediate-Early Genes Affects Infectious-Virus Replication and Control of Cellular Cyclin-Dependent Kinase |
Q33887700 | An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle |
Q38924032 | Analysis of the functional interchange between the IE1 and pp71 proteins of human cytomegalovirus and ICP0 of herpes simplex virus 1. |
Q24670535 | Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86 |
Q38288837 | Binding of cellular repressor protein or the IE2 protein to a cis-acting negative regulatory element upstream of a human cytomegalovirus early promoter. |
Q39876502 | CREB and CREB-binding proteins play an important role in the IE2 86-kilodalton protein-mediated transactivation of the human cytomegalovirus 2.2-kilobase RNA promoter. |
Q33799527 | Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b |
Q39448135 | Cytomegalovirus IE2 protein stimulates interleukin 1beta gene transcription via tethering to Spi-1/PU.1. |
Q35849687 | Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest |
Q36281131 | Deficiencies in Cellular Processes Modulated by the Retinoblastoma Protein Do Not Account for Reduced Human Cytomegalovirus Replication in Its Absence |
Q39764411 | Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses |
Q34014646 | Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysis |
Q33643399 | Effects of human cytomegalovirus major immediate-early proteins in controlling the cell cycle and inhibiting apoptosis: studies with ts13 cells |
Q33851361 | Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9 |
Q33843191 | Exon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation. |
Q39873107 | Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes. |
Q38290895 | Functional interaction between the human cytomegalovirus 86-kilodalton IE2 protein and the cellular transcription factor CREB |
Q34055426 | Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replication |
Q41919640 | Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction |
Q36274309 | Human Cytomegalovirus Immediate Early Interaction with Host Nuclear Structures: Definition of an Immediate Transcript Environment |
Q39596490 | Human cytomegalovirus 86-kilodalton IE2 protein blocks cell cycle progression in G(1). |
Q39872769 | Human cytomegalovirus IE1 and IE2 proteins block apoptosis |
Q33930511 | Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest response |
Q39732633 | Human cytomegalovirus IE2 86 and IE2 40 proteins differentially regulate UL84 protein expression posttranscriptionally in the absence of other viral gene products. |
Q35889716 | Human cytomegalovirus IE2 86-kilodalton protein binds p53 but does not abrogate G1 checkpoint function. |
Q39755438 | Human cytomegalovirus UL84 oligomerization and heterodimerization domains act as transdominant inhibitors of oriLyt-dependent DNA replication: evidence that IE2-UL84 and UL84-UL84 interactions are required for lytic DNA replication |
Q33558299 | Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivate |
Q39874785 | Human cytomegalovirus immediate-early 2 (IE2) protein can transactivate the human hsp70 promoter by alleviation of Dr1-mediated repression |
Q39877362 | Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S. |
Q38379991 | Human cytomegalovirus riding the cell cycle. |
Q35845633 | Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters |
Q39602194 | Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes |
Q39603262 | Identification of a novel transcriptional repressor encoded by human cytomegalovirus |
Q39882060 | Identification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional interaction with each other. |
Q33782285 | Identification of positive and negative regulatory regions involved in regulating expression of the human cytomegalovirus UL94 late promoter: role of IE2-86 and cellular p53 in mediating negative regulatory function. |
Q34546024 | Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication |
Q39940804 | Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomes |
Q35853699 | Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection |
Q39683076 | Novel immediate-early protein IE19 of human cytomegalovirus activates the origin recognition complex I promoter in a cooperative manner with IE72. |
Q33784945 | Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2. |
Q37191856 | Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription |
Q24678703 | Regulation of apoptosis by viral gene products |
Q37085853 | Regulation of the retinoblastoma proteins by the human herpesviruses. |
Q24304994 | Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription |
Q34046161 | Role of noncovalent SUMO binding by the human cytomegalovirus IE2 transactivator in lytic growth |
Q40677826 | Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression. |
Q91866899 | Structured reviews for data and knowledge-driven research |
Q35894831 | TAF-like functions of human cytomegalovirus immediate-early proteins |
Q26825363 | The DNA damage response induced by infection with human cytomegalovirus and other viruses |
Q38333491 | The Epstein-Barr virus immediate-early gene product, BRLF1, interacts with the retinoblastoma protein during the viral lytic cycle |
Q35784878 | The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus. |
Q35870737 | The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site |
Q39881034 | The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication. |
Q34456160 | The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirus |
Q39592549 | The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF. |
Q35872328 | The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter. |
Q39872136 | The human cytomegalovirus IE2 86-kilodalton protein interacts with an early gene promoter via site-specific DNA binding and protein-protein associations |
Q33809143 | The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells |
Q37945177 | The human cytomegalovirus major immediate-early proteins as antagonists of intrinsic and innate antiviral host responses. |
Q40212845 | The putative zinc finger of the human cytomegalovirus IE2 86-kilodalton protein is dispensable for DNA binding and autorepression, thereby demarcating a concise core domain in the C terminus of the protein |
Q35878510 | The role of ATF in regulating the human cytomegalovirus DNA polymerase (UL54) promoter during viral infection. |
Q33781947 | Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells. |
Q33640005 | Transcriptional regulation of the human cytomegalovirus US11 early gene |
Q39878014 | Translational regulation of the human cytomegalovirus pp28 (UL99) late gene |
Q39682884 | Viable human cytomegalovirus recombinant virus with an internal deletion of the IE2 86 gene affects late stages of viral replication |