Heterogeneity of the Epstein-Barr virus major internal repeat reveals evolutionary mechanisms of EBV and a functional defect in the prototype EBV strain B95-8.

scientific article published on 13 September 2017

Heterogeneity of the Epstein-Barr virus major internal repeat reveals evolutionary mechanisms of EBV and a functional defect in the prototype EBV strain B95-8. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00920-17
P932PMC publication ID5686732
P698PubMed publication ID28904201

P50authorPaul KellamQ24005990
Robert E WhiteQ59384394
P2093author name stringRichard D Palermo
Anne L Palser
Mohammed M Ba Abdullah
Nicholas E Grayson
Samantha Correia
Agnieszka Szymula
P2860cites workAn Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 linkQ21131584
Genome-wide analyses of Epstein-Barr virus reveal conserved RNA structures and a novel stable intronic sequence RNAQ21266670
Herpes simplex virus latency-associated transcript is a stable intronQ24564505
VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencingQ24628978
Epstein-barr virus sequence variation-biology and diseaseQ27003183
The Sequence Alignment/Map format and SAMtoolsQ27860966
Noncanonical views of homology-directed DNA repairQ28080032
The enigmatic epidemiology of nasopharyngeal carcinomaQ28268076
Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defensesQ28712008
Sequencing of 21 varicella-zoster virus genomes reveals two novel genotypes and evidence of recombinationQ28732494
Global burden of cancers attributable to infections in 2008: a review and synthetic analysisQ29620303
RDP4: Detection and analysis of recombination patterns in virus genomesQ30394442
The role of DNA repair in herpesvirus pathogenesisQ30458994
Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repairQ30491768
Global transcript structure resolution of high gene density genomes through multi-platform data integrationQ31114225
Identification of a novel latency-specific splice donor signal within the herpes simplex virus type 1 2.0-kilobase latency-associated transcript (LAT): translation inhibition of LAT open reading frames by the intron within the 2.0-kilobase LATQ33238462
Sequence and functional analysis of EBNA-LP and EBNA2 proteins from nonhuman primate lymphocryptovirusesQ33795078
Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A, -3B, and -3C expression in Burkitt's lymphoma cells and with increased resistance to apoptosis.Q33911843
Organization of repeated regions within the Epstein-Barr virus DNA moleculeQ33913142
Alternative splicing dictates translational start in Epstein-Barr virus transcriptsQ33917347
Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platformQ34054922
DNA sequence and expression of the B95-8 Epstein-Barr virus genome.Q34245077
Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsy samples.Q34262322
Human cytomegalovirus intrahost evolution-a new avenue for understanding and controlling herpesvirus infectionsQ34332536
T-RECs: rapid and large-scale detection of recombination events among different evolutionary lineages of viral genomesQ34548629
Identification and characterization of EBV genomes in spontaneously immortalized human peripheral blood B lymphocytes by NGS technologyQ35046901
Epstein-Barr virus mRNAs produced by alternative splicingQ35051384
Determinants of Epstein-Barr virus-positive gastric cancer: an international pooled analysis.Q35108424
Epstein-Barr virus type 2 latently infects T cells, inducing an atypical activation characterized by expression of lymphotactic cytokines.Q35115666
Mixed infection and strain diversity in congenital cytomegalovirus infectionQ35188435
Epstein-Barr virus BamHI W repeat number limits EBNA2/EBNA-LP coexpression in newly infected B cells and the efficiency of B-cell transformation: a rationale for the multiple W repeats in wild-type virus strainsQ35531692
Nucleotide sequences of mRNAs encoding Epstein-Barr virus nuclear proteins: a probable transcriptional initiation siteQ35616566
Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric populationQ35620244
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infectionQ35641421
Rapid genome assembly and comparison decode intrastrain variation in human alphaherpesvirusesQ35677486
Genomic, phylogenetic, and recombinational characterization of herpes simplex virus 2 strainsQ35760461
EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumorsQ35858022
High-throughput analysis of human cytomegalovirus genome diversity highlights the widespread occurrence of gene-disrupting mutations and pervasive recombinationQ35861195
Isolation of intertypic recombinants of Epstein-Barr virus from T-cell-immunocompromised individualsQ35865472
Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activationQ35891360
Limits and patterns of cytomegalovirus genomic diversity in humansQ35910248
Genome Sequencing and Analysis of Geographically Diverse Clinical Isolates of Herpes Simplex Virus 2.Q35914336
Targeted genomic enrichment and sequencing of CyHV-3 from carp tissues confirms low nucleotide diversity and mixed genotype infectionsQ36153206
Propagation and recovery of intact, infectious Epstein-Barr virus from prokaryotic to human cellsQ36173276
Clusters of Multiple Mutations: Incidence and Molecular MechanismsQ36455998
Genome-wide Analysis of Epstein-Barr Virus (EBV) Integration and Strain in C666-1 and Raji Cells.Q36473933
DNA of Epstein-Barr virus. VI. Mapping of the internal tandem reiterationQ36500605
Whole-genome sequencing of the Akata and Mutu Epstein-Barr virus strainsQ36559612
Highly Efficient CRISPR/Cas9-Mediated Cloning and Functional Characterization of Gastric Cancer-Derived Epstein-Barr Virus StrainsQ36812001
Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcrQ36908739
Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell linesQ36920279
Long internal direct repeat in Epstein-Barr virus DNAQ36925615
Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, JijoyeQ36927515
Mechanisms of ectopic gene conversionQ37136141
Evolution and diversity in human herpes simplex virus genomesQ37547447
Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytesQ37707304
Epstein-Barr virus genetics: talking about the BAC generationQ37856451
Recombination in viruses: mechanisms, methods of study, and evolutionary consequences.Q38301018
Complete genomic sequence of Epstein-Barr virus in nasopharyngeal carcinoma cell line C666-1.Q39115333
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphomaQ39171041
Toward a comprehensive phylogeny for mammalian and avian herpesvirusesQ39585334
Novel intertypic recombinants of epstein-barr virus in the chinese populationQ39588391
Cellular gene expression that correlates with EBER expression in Epstein-Barr Virus-infected lymphoblastoid cell linesQ39605687
Deletion of Epstein-Barr virus regulatory sequences upstream of the EBNA gene promoter Wp1 is unfavorable for B-Cell immortalizationQ39685900
Nuclear-cytoplasmic shuttling is not required for the Epstein-Barr virus EBNA-LP transcriptional coactivation functionQ39858749
Influence of the Epstein-Barr virus nuclear antigen EBNA 2 on the growth phenotype of virus-transformed B cellsQ40132148
Recovery of Epstein-Barr virus from nonproducer neonatal human lymphoid cell transformantsQ40241663
Characterization of the deletion and rearrangement in the BamHI C region of the X50-7 Epstein-Barr virus genome, a mutant viral strain which exhibits constitutive BamHI W promoter activityQ40309345
Development of a monoclonal antibody against Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) that can detect EBNA-LP expressed in P3HR1 cellsQ40419718
Geographic Population Structure in Epstein-Barr Virus Revealed by Comparative GenomicsQ40446900
Clustered repeat sequences in the genome of Epstein Barr virusQ40491701
Updated Epstein-Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV.Q40585890
Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2.Q40705440
Genetic analysis of the Epstein-Barr virus-coded leader protein EBNA-LP as a co-activator of EBNA2 functionQ40767553
An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsive to therapy with virus-specific CTLsQ40830952
The EB virus genome in Daudi Burkitt's lymphoma cells has a deletion similar to that observed in a non-transforming strain (P3HR-1) of the virus.Q41568680
The genome of Epstein-Barr virus type 2 strain AG876.Q45419603
Characterization of Epstein-Barr virus Type I variants based on linked polymorphism among EBNA3A, -3B, and -3C genesQ45420931
Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome.Q50535712
A Modified Bootscan Algorithm for Automated Identification of Recombinant Sequences and Recombination BreakpointsQ56878359
P4510describes a project that usesRStudioQ4798119
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
P577publication date2017-09-13
P1433published inJournal of VirologyQ1251128
P1476titleHeterogeneity of the Epstein-Barr virus major internal repeat reveals evolutionary mechanisms of EBV and a functional defect in the prototype EBV strain B95-8.
P478volume91

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cites work (P2860)
Q91722829A reliable Epstein-Barr Virus classification based on phylogenomic and population analyses
Q50535712Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome.
Q64118196Epstein-Barr virus strain variation and cancer
Q64068003Essential role of inverted repeat in Epstein-Barr virus IR-1 in B cell transformation; geographical variation of the viral genome
Q90722657Human Herpesvirus Sequencing in the Genomic Era: The Growing Ranks of the Herpetic Legion
Q56529299Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays
Q58706090Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases

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