scholarly article | Q13442814 |
P2093 | author name string | T. Friedmann | |
P. A. Johnson | |||
A. Miyanohara | |||
F. Levine | |||
T. Cahill | |||
P2860 | cites work | Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor | Q24561804 |
Herpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice | Q24645922 | ||
Detection of specific sequences among DNA fragments separated by gel electrophoresis | Q25939003 | ||
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity | Q26778490 | ||
A new technique for the assay of infectivity of human adenovirus 5 DNA | Q27860797 | ||
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation | Q28263551 | ||
Characterization of the IE110 gene of herpes simplex virus type 1 | Q28287831 | ||
Cell death: the significance of apoptosis | Q29617620 | ||
Herpes simplex virus type 1 latency-associated transcripts are evidently not essential for latent infection | Q33559492 | ||
Molecular engineering of the herpes simplex virus genome: Insertion of a second L-S junction into the genome causes additional genome inversions | Q34251950 | ||
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes | Q34272920 | ||
Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouse | Q34308944 | ||
Limited bidirectional activity of two housekeeping gene promoters: human HPRT and PGK. | Q34332031 | ||
A common progenitor for neurons and glia persists in rat retina late in development | Q34691194 | ||
Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulation | Q35585442 | ||
Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides | Q36129181 | ||
Multiple influences of a heparin-binding growth factor on neuronal development | Q36216368 | ||
Herpes simplex virus for gene delivery to neurons. | Q36416048 | ||
Isolation of a herpes simplex virus type 1 mutant deleted for the essential UL42 gene and characterization of its null phenotype | Q36679955 | ||
Induction of the TRPM-2 gene in cells undergoing programmed death | Q36759106 | ||
Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient | Q36779897 | ||
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency | Q36780729 | ||
Repair replication of viral and cellular DNA in herpes simplex virus type 2-infected human embryonic and xeroderma pigmentosum cells | Q45802305 | ||
Herpes simplex virus latency in cultured human cells following treatment with cytosine arabinoside | Q45820884 | ||
Early events required for induction of chromosome abnormalities in human cells by herpes simplex virus | Q45821084 | ||
Physical state of the latent herpes simplex virus genome in a mouse model system: evidence suggesting an episomal state | Q45834725 | ||
Herpes simplex virus gene products involved in the induction of chromosomal aberrations | Q45834858 | ||
Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110. | Q45835577 | ||
Chromosome damage induced by herpes simplex virus type 1 in early infection | Q45836052 | ||
Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1. | Q45838888 | ||
Interferon treatment inhibits onset of herpes simplex virus immediate-early transcription | Q45841630 | ||
Purification of a set of cellular polypeptides that bind to the purine-rich cis-regulatory element of herpes simplex virus immediate early genes | Q45844904 | ||
Comparative DNA sequence analysis of the host shutoff genes of different strains of herpes simplex virus: type 2 strain HG52 encodes a truncated UL41 product | Q45851354 | ||
Nerve growth factor-dependence of herpes simplex virus latency in peripheral sympathetic and sensory neurons in vitro | Q45851566 | ||
Herpes simplex virus latent phase transcription facilitates in vivo reactivation | Q45851971 | ||
Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis | Q45859903 | ||
A latent, nonpathogenic HSV-1-derived vector stably expresses beta-galactosidase in mouse neurons | Q46135759 | ||
Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control | Q46168479 | ||
The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes | Q68450332 | ||
RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons | Q68986775 | ||
During latency, herpes simplex virus type 1 DNA is associated with nucleosomes in a chromatin structure | Q36781005 | ||
A herpes simplex virus type 1 mutant containing a nontransinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia | Q36803575 | ||
Chromosomal damage induced by human adenovirus type 12 requires expression of the E1B 55-kilodalton viral protein | Q36805605 | ||
Specific effect of interferon on the herpes simplex virus type 1 transactivation event | Q36806771 | ||
Differential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant | Q36812408 | ||
A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency | Q36829179 | ||
Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein | Q36832257 | ||
Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. | Q36853238 | ||
The herpes simplex virus latency-associated transcript is spliced during the latent phase of infection | Q36873719 | ||
Herpes simplex virus virion host shutoff function | Q36876283 | ||
Bacterial beta-galactosidase as a marker of Rous sarcoma virus gene expression and replication | Q36885381 | ||
Identification of a herpes simplex virus function that represses late gene expression from parental viral genomes | Q36903230 | ||
Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides | Q36905949 | ||
Detection of herpes simplex virus type 1 transcripts during latent infection in mice | Q36920237 | ||
Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques | Q36952733 | ||
Human herpesviruses: a consideration of the latent state | Q37055693 | ||
Expression of hepatitis B virus S gene by herpes simplex virus type 1 vectors carrying alpha- and beta-regulated gene chimeras | Q37568940 | ||
Requirement of protein synthesis for the degradation of host mRNA in Friend erythroleukemia cells infected wtih herpes simplex virus type 1 | Q37601252 | ||
Infection of cultured central nervous system neurons with a defective herpes simplex virus 1 vector results in stable expression of Escherichia coli beta-galactosidase | Q37689072 | ||
Genetic engineering of novel genomes of large DNA viruses | Q39496201 | ||
The role of nucleotides in human fragile site expression | Q39652387 | ||
DNA repair replication in human embryonic lung cells infected with herpes simplex virus | Q40109030 | ||
Suppression of the Synthesis of Cellular Macromolecules by Herpes Simplex Virus | Q40179203 | ||
Physical mapping across the fragile X: hypermethylation and clinical expression of the fragile X syndrome | Q41178713 | ||
Establishment of latency in vitro by the herpes simplex virus type 1 mutant in 1814 | Q41689516 | ||
Insertion of DNA sequences at a unique restriction enzyme site engineered for vector purposes into the genome of herpes simplex virus type 1. | Q41712306 | ||
Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants | Q41726334 | ||
A prominent serine-rich region in Vmw175, the major transcriptional regulator protein of herpes simplex virus type 1, is not essential for virus growth in tissue culture | Q41726497 | ||
Transfer of UL41, the gene controlling virion-associated host cell shutoff, between different strains of herpes simplex virus | Q41745774 | ||
A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons | Q43244050 | ||
Loss of surface fibronectin after infection of cultured cells by HSV-1 and 2. | Q43963116 | ||
Involvement of actin-containing microfilaments in HSV-induced cytopathology and the influence of inhibitors of glycosylation | Q44139882 | ||
Inhibition of transcription of herpes simplex virus immediate early genes in interferon-treated human cells | Q44185838 | ||
Expression of an immediate early polypeptide and activation of a viral origin of DNA replication in cells containing a fragment of herpes simplex virus DNA. | Q44362217 | ||
The herpes simplex virus amplicon: A new eucaryotic defective-virus cloning-amplifying vector | Q44397432 | ||
Octamer motif mediates transcriptional repression of HSV immediate-early genes and octamer-containing cellular promoters in neuronal cells | Q44617921 | ||
VIRUSES AND MAMMALIAN CHROMOSOMES. I. LOCALIZATION OF CHROMOSOME ABERRATIONS AFTER INFECTION WITH HERPES SIMPLEX VIRUS. | Q45714789 | ||
THE MULTIPLICATION OF HERPES SIMPLEX VIRUS. II. THE RELATION BETWEEN PROTEIN SYNTHESIS AND THE DUPLICATION OF VIRAL DNA IN INFECTED HEP-2 CELLS. | Q45714857 | ||
Chromosomal aberrations induced by an animal virus | Q45716883 | ||
Effects of gene transfer into cultured CNS neurons with a replication-defective herpes simplex virus type 1 vector | Q45729782 | ||
Herpes simplex virus genes involved in latency in vitro | Q45732292 | ||
Herpes Simplex Virus Latency: the Cellular Location of Virus in Dorsal Root Ganglia and the Fate of the Infected Cell Following Virus Activation | Q45802213 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cytotoxicity | Q246181 |
genetic vector | Q427389 | ||
viral genome replication | Q3933202 | ||
P304 | page(s) | 2952-2965 | |
P577 | publication date | 1992-05-01 | |
P1433 | published in | Journal of Virology | Q1251128 |
P1476 | title | Cytotoxicity of a replication-defective mutant of herpes simplex virus type 1 | |
P478 | volume | 66 |
Q35222291 | A brief history of gene therapy |
Q35873295 | A hybrid herpesvirus infectious vector based on Epstein-Barr virus and herpes simplex virus type 1 for gene transfer into human cells in vitro and in vivo |
Q34286445 | A limited innate immune response is induced by a replication-defective herpes simplex virus vector following delivery to the murine central nervous system |
Q36680208 | Activation of H2AX and ATM in varicella-zoster virus (VZV)-infected cells is associated with expression of specific VZV genes |
Q35995307 | Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice |
Q40524547 | Advances in cancer gene therapy |
Q40422915 | African green monkey kidney Vero cells require de novo protein synthesis for efficient herpes simplex virus 1-dependent apoptosis |
Q35857229 | Alphavirus-induced apoptosis in mouse brains correlates with neurovirulence. |
Q40571051 | Amplicon-based herpes simplex virus vectors. |
Q40137260 | An HSV-1 amplicon system for prostate-specific expression of ICP4 to complement oncolytic viral replication for in vitro and in vivo treatment of prostate cancer cells |
Q45862004 | An efficient in vivo recombination cloning procedure for modifying and combining HSV-1 cosmids |
Q39580097 | An enhanced packaging system for helper-dependent herpes simplex virus vectors |
Q45754375 | Analysis of a multi-mutant herpes simplex virus type 1 for gene transfer into sympathetic preganglionic neurons and a comparison to adenovirus vectors |
Q41526877 | Anti-oncogene Ribozymes for Cancer Gene Therapy |
Q43934769 | Antitumor effects on human melanoma xenografts of an amplicon vector transducing the herpes thymidine kinase gene followed by ganciclovir |
Q36707752 | Apoptosis during herpes simplex virus infection |
Q40551607 | Apoptosis in viral infections |
Q74639680 | Cancer gene therapy |
Q45741299 | Chronic lymphocytic leukemia B cells are highly sensitive to infection by herpes simplex virus-1 via herpesvirus-entry-mediator A. |
Q45746815 | Delivery of herpes simplex virus amplicon-based vectors to the dentate gyrus does not alter hippocampal synaptic transmission in vivo |
Q33873085 | Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption |
Q39591444 | Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system |
Q40908487 | Effects of herpes simplex virus on human oral cancer cells, and potential use of mutant viruses in therapy of oral cancer |
Q62971299 | Engineering Herpes Simplex |
Q40803029 | Enhanced reporter gene expression in the rat brain from helper virus-free HSV-1 vectors packaged in the presence of specific mutated HSV-1 proteins that affect the virion |
Q44079762 | Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus |
Q39550929 | Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defects |
Q45754922 | Expression of the human immunodeficiency virus gag gene products by a replication-incompetent herpes simplex virus vector |
Q40606308 | Functional expression of ATM gene carried by HSV amplicon vector in vitro and in vivo |
Q45773320 | Gene delivery into the brain using virus vectors |
Q33917592 | Gene delivery with viral vectors for cerebrovascular diseases |
Q34997896 | Gene therapy for the central nervous system in the lysosomal storage disorders |
Q71653280 | Gene therapy for urologic cancer |
Q24680275 | Gene therapy in clinical medicine |
Q42113935 | General strategy for constructing large HSV-1 plasmid vectors that co-express multiple genes |
Q33857478 | HIV protease as a target for retrovirus vector-mediated gene therapy |
Q40922461 | HSV as a gene transfer vector for the nervous system |
Q36288901 | HSV-1-based amplicon vectors: design and applications |
Q33995752 | HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applications |
Q40769181 | Helper virus-free HSV-1 vectors packaged both in the presence of VSV G protein and in the absence of HSV-1 glycoprotein B support gene transfer into neurons in the rat striatum |
Q35870965 | Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells. |
Q40604183 | Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS. |
Q45747421 | Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo |
Q58779571 | Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System |
Q36444443 | Herpes simplex virus 1 (HSV-1) for cancer treatment |
Q36898823 | Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanism |
Q39596594 | Herpes simplex virus type 1 immediate-early protein Vmw110 inhibits progression of cells through mitosis and from G(1) into S phase of the cell cycle. |
Q34070145 | Herpes simplex virus type 1-based amplicon vector systems |
Q40395117 | Herpes simplex virus type-1 amplicon vectors for vaccine generation in acute lymphoblastic leukemia |
Q45788035 | Herpes simplex virus vector system: analysis of its in vivo and in vitro cytopathic effects |
Q35863367 | Herpes simplex virus-based vectors |
Q37160338 | High-level expression of glycoprotein D by a dominant-negative HSV-1 virus augments its efficacy as a vaccine against HSV-1 infection |
Q40728386 | Human cytomegalovirus tegument protein pp71 directs long-term gene expression from quiescent herpes simplex virus genomes |
Q41495440 | ICP0 gene expression is a herpes simplex virus type 1 apoptotic trigger |
Q34545788 | ICP0 is not required for efficient stress-induced reactivation of herpes simplex virus type 1 from cultured quiescently infected neuronal cells |
Q37392882 | Immune responses to herpesviral vectors |
Q35131218 | Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy |
Q62971278 | Implications of maturation for viral gene delivery to skeletal muscle |
Q40041827 | Improved cell survival by the reduction of immediate-early gene expression in replication-defective mutants of herpes simplex virus type 1 but not by mutation of the virion host shutoff function. |
Q33468717 | Improved long-term expression from helper virus-free HSV-1 vectors packaged using combinations of mutated HSV-1 proteins that include the UL13 protein kinase and specific components of the VP16 transcriptional complex |
Q48529105 | In vivo gene transfer into the adult mammalian central nervous system by continuous injection of plasmid DNA-cationic liposome complex |
Q39579065 | Increased induction of apoptosis by a Sendai virus mutant is associated with attenuation of mouse pathogenicity |
Q77802801 | Infection and spread of alphaherpesviruses in the nervous system |
Q39876184 | Inhibition of herpes simplex virus type 1 immediate-early gene expression by alpha interferon is not VP16 specific |
Q44974102 | Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus |
Q42280576 | Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain |
Q43244057 | Long-term inducible expression in striatal neurons from helper virus-free HSV-1 vectors that contain the tetracycline-inducible promoter system |
Q34387794 | Modulation of apoptosis during herpes simplex virus infection in human cells |
Q40814855 | Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo |
Q44943020 | Muscle maturation: implications for gene therapy |
Q42805617 | Nerve growth factor somatic mosaicism produced by herpes virus-directed expression of cre recombinase |
Q33783411 | Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins |
Q37363640 | Prevention of hepatic tumor metastases in rats with herpes viral vaccines and gamma-interferon |
Q43524051 | Progress in development of herpes simplex virus gene vectors for treatment of rheumatoid arthritis |
Q35868577 | Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22. |
Q41982319 | Prospects for the use of artificial chromosomes and minichromosome-like episomes in gene therapy. |
Q45868232 | Rapid and efficient gene transfer in human hepatocytes by herpes viral vectors |
Q45889730 | Recent developments in gene therapy for oncology and hematology |
Q34080884 | Recognition of virus infection and innate host responses to viral gene therapy vectors |
Q39882313 | Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap |
Q37248260 | Replication-defective herpes simplex virus vectors for gene transfer in vivo |
Q40571058 | Replication-defective recombinant herpes simplex virus vectors. |
Q36574880 | Replication-incompetent herpesvirus vector delivery of an interferon alpha gene inhibits human immunodeficiency virus replication in human monocytes |
Q47832394 | Reproducible and efficient murine CNS gene delivery using a microprocessor-controlled injector |
Q42801965 | Susceptibility to cytotoxic T lymphocyte-induced apoptosis is a function of the proliferative status of the target |
Q35886888 | The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27 |
Q33643356 | The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells |
Q35131100 | Toxicity and biodistribution of the serotype 2 recombinant adeno-associated viral vector, encoding Aquaporin-1, after retroductal delivery to a single mouse parotid gland |
Q64377820 | Transfer of a foreign gene into the brain using adenovirus vectors |
Q33824256 | Truncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 renders expression of the immediate-early genes almost entirely dependent on ICP0 |
Q35903203 | Update on herpesvirus amplicon vectors |
Q45754297 | Use of recombinant herpes simplex virus type 1 vectors for gene transfer into tumour and normal anterior pituitary cells |
Q39149034 | Viral Vector Biosafety in Laboratory Animal Research |
Q45864370 | Viral oncoapoptosis of human tumor cells |
Q41235446 | Viral vectors for modulating gene expression in neurons |
Q33894621 | Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNS |