Identification of EGF receptor C-terminal sequences 1005-1017 and di-leucine motif 1010LL1011 as essential in EGF receptor endocytosis

scientific article

Identification of EGF receptor C-terminal sequences 1005-1017 and di-leucine motif 1010LL1011 as essential in EGF receptor endocytosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXCR.2007.06.014
P698PubMed publication ID17643422

P2093author name stringZhixiang Wang
Qian Wang
Fuxiang Zhu
P2860cites workTyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogeneQ28286890
Signals for sorting of transmembrane proteins to endosomes and lysosomesQ29547469
Growth factor signaling by receptor tyrosine kinasesQ29618315
EGF-ERBB signalling: towards the systems levelQ29619032
Signal-dependent membrane protein trafficking in the endocytic pathwayQ29622948
Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pitsQ30159982
Phospholipase C-gamma1 is a guanine nucleotide exchange factor for dynamin-1 and enhances dynamin-1-dependent epidermal growth factor receptor endocytosisQ30163945
Grb2 regulates internalization of EGF receptors through clathrin-coated pitsQ30164836
Requirement for the adapter protein GRB2 in EGF receptor endocytosisQ30176918
Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosisQ30469765
Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosisQ30856504
A novel dileucine lysosomal-sorting-signal mediates intracellular EGF-receptor retention independently of protein ubiquitylation.Q31000323
Recognition of sorting signals by clathrin adaptorsQ33725676
Clathrin-independent endocytosis of ubiquitinated cargosQ33864329
Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteinsQ33921286
Receptors for epidermal growth factor and other polypeptide mitogensQ34163558
Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular bodyQ34330127
Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosisQ36328720
The SRC homology 2 domain of Rin1 mediates its binding to the epidermal growth factor receptor and regulates receptor endocytosisQ38353980
Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motifQ38356797
Phosphorylation of tyrosine 992, 1068, and 1086 is required for conformational change of the human epidermal growth factor receptor c-terminal tailQ38609896
Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulationQ38669920
Allosteric regulation of the epidermal growth factor receptor kinaseQ39505742
Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survivalQ39695672
Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activationQ40382842
A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomesQ40978824
EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.Q41615790
Kinetics of binding, endocytosis, and recycling of EGF receptor mutantsQ41631112
Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor traffickingQ44538219
Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodiesQ46979793
Endocytosis proteins and cancer: a potential link?Q47686987
Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptorQ59054268
Interaction of activated EGF receptors with coated pit adaptinsQ72858669
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)3349-3363
P577publication date2007-06-30
P1433published inExperimental Cell ResearchQ1524289
P1476titleIdentification of EGF receptor C-terminal sequences 1005-1017 and di-leucine motif 1010LL1011 as essential in EGF receptor endocytosis
P478volume313

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cites work (P2860)
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Q39688031Dimerization drives PDGF receptor endocytosis through a C-terminal hydrophobic motif shared by EGF receptor
Q37343076Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.
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