Functional Implications of Gene Dosage Effects in Trisomy 21

scientific article published on January 1, 1981

Functional Implications of Gene Dosage Effects in Trisomy 21 is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/978-3-642-68006-9_12
P953full work available at URLhttps://link.springer.com/content/pdf/10.1007/978-3-642-68006-9_12
P698PubMed publication ID6185454

P2093author name stringD. R. Cox
C. J. Epstein
J. Weil
L. B. Epstein
P2860cites workMouse News LetterQ22023346
The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21Q24679138
Texas Reports on Biology and MedicineQ26808291
Chromosome 21 and the cell growth inhibitory effect of human interferon preparationsQ34656845
Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16Q36364578
Letter: Superoxide dismutase in Down syndromeQ39333517
Dosage effect of SOD-A gene in 21-trisomic cellsQ39758590
Lymphoblastogenesis in Down's syndrome and its inhibition by human interferonQ39863621
Down's syndrome and acute leukemia: myeloblastic or lymphoblastic? Report of forty-three cases and review of the literatureQ39886012
Familial hypercholesterolemia. A genetic regulatory defect in cholesterol metabolismQ39920068
Use of mutant fibroblasts in the analysis of the regulation of cholesterol metabolism in human cellsQ39924668
Localization of the Gene AVG for the Antiviral Expression of Immune and Classical Interferon to the Distal Portion of the Long Arm of Chromosome 21Q39996635
Systematic approach to the study of trisomy in the mouse. IIQ41532384
Confirmation of the assignment of the human SODS gene to chromosome 21q22.Q43579732
Chromosome variation and gene actionQ44561363
Synthesis of Interferon-Induced Polypeptides in Normal and Chromosome 21-Aneuploid Human Fibroblasts: Relationship to Relative Sensitivities in Antiviral AssaysQ44730845
Effect of priming on interferon inhibition of con A induced spleen cell blastogenesis.Q44790176
Effect of human interferon preparations on lymphoblastogenesis in Down's syndromeQ47965026
Biochemical characterization of six trisomics of grain sorghum, Sorghum bicolor (L.) MoenchQ50953591
Some thoughts on a possible relationship between known gene dosage effects and neoplastic transformation.Q53600255
Antibodies to a cell-surface component coded by human chromosome 21 inhibit action of interferonQ59064916
Regulation of chromosome 21-directed anti-viral gene(s) as a consequence of ageQ59064938
Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis)Q59064946
Inhibition of interferon action by plant lectinsQ59064960
Chromosome Redundancy and Gene Expression: an Explanation for Trisomy AbnormalitiesQ59065041
Gene dosage for isocitrate dehydrogenase in mouse embryos trisomic for chromosome 1Q59065045
Dr A. S. RussellQ59074404
Increase in glutathione peroxidase activity in erythrocytes from trisomy 21 subjectsQ67348607
Trisomy 21 and superoxide dismutase-1 (IPO-A). Tentative localization of sub-band 21Q22.1Q67432394
Impaired in vitro response of circulating lymphocytes to phytohemagglutinin in Down's syndrome: dose- and time-response curves and relation to cellular immunityQ68465947
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral stateQ68699779
Trisomy in the fetal backcross progeny of male and female metacentric heterozygotes of the mouse. iQ68899007
Gene dosage effect for glycinamide ribonucleotide synthetase in human fibroblasts trisomic for chromosome 21Q70529145
T-lymphocyte function and sensitivity to interferon in trisomy 21Q72607630
Reversible inhibition by interferon of the maturation of human peripheral blood monocytes to macrophagesQ72613391
Enhanced sensitivity of trisomy 21 monocytes to the maturation-inhibiting effect of interferonQ72613395
P407language of work or nameEnglishQ1860
P304page(s)155-172
P577publication date1981-01-01
P1433published inHuman genetics. SupplementQ27711312
P1476titleFunctional Implications of Gene Dosage Effects in Trisomy 21
P478volume2

Reverse relations

cites work (P2860)
Q37615256Analysis of two-dimensional protein patterns from mouse embryos with different trisomies
Q33236637Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21.
Q41547473Developmental pathogenesis of chromosome disorders: Report on two newly recognized signs of down syndrome
Q46652242Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome
Q70180242Interferon induction of (2??5?) oligoisoadenylate synthetase in diploid and trisomy 21 human fibroblasts: Relation to dosage of the interferon receptor gene (IRFC)
Q28588697Overexpression of liver-type phosphofructokinase (PFKL) in transgenic-PFKL mice: implication for gene dosage in trisomy 21
Q41907866Overproduction of human Cu/Zn-superoxide dismutase in transfected cells: extenuation of paraquat-mediated cytotoxicity and enhancement of lipid peroxidation
Q35882394Statistical models for trisomic phenotypes.

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