AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes

scientific article

AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1271/BBB.70057
P698PubMed publication ID17617726
P5875ResearchGate publication ID5288529

P2093author name stringKazuki Nakashima
Yoko Yakabe
P433issue7
P304page(s)1650-1656
P577publication date2007-07-07
P1433published inBioscience, Biotechnology, and BiochemistryQ11192374
P1476titleAMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes
P478volume71

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cites work (P2860)
Q54389842AICAR-induced activation of AMPK negatively regulates myotube hypertrophy through the HSP72-mediated pathway in C2C12 skeletal muscle cells.
Q89551502AMP-Activated Protein Kinase (AMPK) at the Crossroads Between CO2 Retention and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease (COPD)
Q36756228AMP-activated protein kinase and its downstream transcriptional pathways
Q42704686AMP-activated protein kinase mediates the antioxidant effects of resveratrol through regulation of the transcription factor FoxO1.
Q35661532AMP-activated protein kinase regulates E3 ligases in rodent heart
Q59134223AMPK Mediates Muscle Mass Change But Not the Transition of Myosin Heavy Chain Isoforms during Unloading and Reloading of Skeletal Muscles in Mice
Q44948044AMPK inhibits myoblast differentiation through a PGC-1alpha-dependent mechanism.
Q33557470Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro
Q51573173Adenosine monophosphate-activated protein kinase attenuates cardiomyocyte hypertrophy through regulation of FOXO3a/MAFbx signaling pathway.
Q37801870Adiponectin action from head to toe.
Q48245764Adiponectin inhibits inflammatory cytokines production by Beclin-1 phosphorylation and Bcl-2 mRNA destabilization: Role for autophagy induction.
Q44866508Asparagine reduces the mRNA expression of muscle atrophy markers via regulating protein kinase B (Akt), AMP-activated protein kinase α, toll-like receptor 4 and nucleotide-binding oligomerisation domain protein signalling in weaning piglets after li
Q40381038Aspartate inhibits LPS-induced MAFbx and MuRF1 expression in skeletal muscle in weaned pigs by regulating Akt, AMPKα and FOXO1.
Q38189267Autophagic cellular responses to physical exercise in skeletal muscle.
Q27000625Autophagy is essential to support skeletal muscle plasticity in response to endurance exercise
Q48181999Branched-chain amino acids administration suppresses endurance exercise-related activation of ubiquitin proteasome signaling in trained human skeletal muscle.
Q30252733Caloric restriction extends yeast chronological lifespan by optimizing the Snf1 (AMPK) signaling pathway
Q36767838Calorie restriction: is AMPK a key sensor and effector?
Q36956035Calpain activity and muscle wasting in sepsis
Q27012762Cellular and molecular mechanisms of muscle atrophy
Q42228159Chronic 5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside Treatment Induces Phenotypic Changes in Skeletal Muscle, but Does Not Improve Disease Outcomes in the R6/2 Mouse Model of Huntington's Disease
Q36309131Co-ingestion of carbohydrate and whey protein increases fasted rates of muscle protein synthesis immediately after resistance exercise in rats
Q91938273Deficiency of fibroblast growth factor 21 aggravates obesity-induced atrophic responses in skeletal muscle
Q33564256Denervation does not Induce Muscle Atrophy Through Oxidative Stress
Q91910488Dietary Aronia melanocarpa extract enhances mTORC1 signaling, but has no effect on protein synthesis and protein breakdown-related signaling, in response to resistance exercise in rat skeletal muscle
Q41379113Dietary supplementation of β-guanidinopropionic acid (βGPA) reduces whole-body and skeletal muscle growth in young CD-1 mice
Q37137271Does AMP-activated protein kinase negatively mediate aged fast-twitch skeletal muscle mass?
Q59798813Effect of Ninjin’yoeito on the Loss of Skeletal Muscle Function in Cancer-Bearing Mice
Q83972043Effects of leptin and adiponectin on proliferation and protein metabolism of porcine myoblasts
Q89661930Effects of tannase-converted green tea extract on skeletal muscle development
Q54385382Exercise-induced AMPK activation does not interfere with muscle hypertrophy in response to resistance training in men.
Q36531919Expression of Transcription Factor FOXO3a is Decreased in Patients with Ulcerative Colitis
Q38162721FoxO transcription factors: their roles in the maintenance of skeletal muscle homeostasis
Q37701112Foxo/atrogin induction in human and experimental myositis
Q37855653Functional adiponectin resistance and exercise intolerance in heart failure.
Q55331913Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress.
Q35580888High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1).
Q37690120IGF-1 potentiates sensory innervation signalling by modulating the mitochondrial fission/fusion balance
Q38759079Independent AMP and NAD signaling regulates C2C12 differentiation and metabolic adaptation
Q93098906Influence of shortened recovery between resistance exercise sessions on muscle-hypertrophic effect in rat skeletal muscle
Q36185141Insulin down-regulates the expression of ubiquitin E3 ligases partially by inhibiting the activity and expression of AMP-activated protein kinase in L6 myotubes
Q33840333Insulin effects on glucose tolerance, hypermetabolic response, and circadian-metabolic protein expression in a rat burn and disuse model
Q26765148Insulin resistance and sarcopenia: mechanistic links between common co-morbidities
Q38064396Intensive care unit-acquired weakness: clinical phenotypes and molecular mechanisms.
Q38204299Interference between concurrent resistance and endurance exercise: molecular bases and the role of individual training variables
Q34597522Intracellular signaling pathways regulating net protein balance following diaphragm muscle denervation.
Q52926464Involvement of AMPK in regulating slow-twitch muscle atrophy during hindlimb unloading in mice.
Q55062189L-Alanylglutamine inhibits signaling proteins that activate protein degradation, but does not affect proteins that activate protein synthesis after an acute resistance exercise.
Q27342830Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice
Q36422693Lewis lung carcinoma regulation of mechanical stretch-induced protein synthesis in cultured myotubes
Q42944434Lysine suppresses myofibrillar protein degradation by regulating the autophagic-lysosomal system through phosphorylation of Akt in C2C12 cells
Q34572209MST1, a key player, in enhancing fast skeletal muscle atrophy
Q38165141Mechanical properties of respiratory muscles
Q64274537Mechanisms Underlying Metabolic Syndrome-Related Sarcopenia and Possible Therapeutic Measures
Q36103986Mechanisms of Cachexia in Chronic Disease States
Q28541996Metformin protects cardiomyocyte from doxorubicin induced cytotoxicity through an AMP-activated protein kinase dependent signaling pathway: an in vitro study
Q34265028Minireview: hey U(PS): metabolic and proteolytic homeostasis linked via AMPK and the ubiquitin proteasome system
Q39713513Mitochondrial fission and remodelling contributes to muscle atrophy.
Q48066927Molecular characterization and association analysis of FBXO40 with partial hematological indexes in pig.
Q37138465Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia
Q34085586Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.
Q38303979Muscle wasting in disease: molecular mechanisms and promising therapies
Q92898593Network Pharmacology-Based Investigation into the Mechanisms of Quyushengxin Formula for the Treatment of Ulcerative Colitis
Q34652034PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting
Q24634396Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy
Q47811763Pharmacological targeting of exercise adaptations in skeletal muscle: Benefits and pitfalls
Q37893657Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networks
Q85053744Quercetin Prevents Unloading-Derived Disused Muscle Atrophy by Attenuating the Induction of Ubiquitin Ligases in Tail-Suspension Mice
Q37912719Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass
Q34756301Regulation of AMPK by the ubiquitin proteasome system
Q37484275Regulation of skeletal muscle oxidative capacity and muscle mass by SIRT3.
Q86999646Respiratory muscle plasticity
Q64259074Resveratrol prevents sarcopenic obesity by reversing mitochondrial dysfunction and oxidative stress via the PKA/LKB1/AMPK pathway
Q37000179Sepsis and AMPK Activation by AICAR Differentially Regulate FoxO-1, -3 and -4 mRNA in Striated Muscle
Q39032975THE RENIN-ANGIOTENSIN SYSTEM AND THE BIOLOGY OF SKELETAL MUSCLE: MECHANISMS OF MUSCLE WASTING IN CHRONIC DISEASE STATES.
Q55653938The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting.
Q57476059The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration
Q51396253The effect of four different feeding regimens from rearing period to sexual maturity on breast muscle protein turnover in broiler breeder parent stock.
Q47314372The effects of dietary β-guanidinopropionic acid on growth and muscle fiber development in juvenile red porgy, Pagrus pagrus
Q34031423The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse

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