AICAR-induced activation of AMPK negatively regulates myotube hypertrophy through the HSP72-mediated pathway in C2C12 skeletal muscle cells.

scientific article published on 17 December 2013

AICAR-induced activation of AMPK negatively regulates myotube hypertrophy through the HSP72-mediated pathway in C2C12 skeletal muscle cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPENDO.00495.2013
P698PubMed publication ID24347059
P5875ResearchGate publication ID259352944

P50authorTatsuro EgawaQ59691885
P2093author name stringMiho Suzuki
Shingo Yokoyama
Akihiro Ikuta
Ayumi Goto
Katsumasa Goto
Takao Sugiura
Tomotaka Ohira
Toshitada Yoshioka
Yoshinobu Ohira
Yoshitaka Ohno
P2860cites workImpaired overload-induced hypertrophy in obese Zucker rat slow-twitch skeletal muscleQ45295320
Important role for AMPKalpha1 in limiting skeletal muscle cell hypertrophyQ46112113
AMPK activation by AICAR inhibits myogenic differentiation and myostatin expression in CattleQ54509123
Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTORQ24608321
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiationQ24650204
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signalingQ28216932
MicroRNA-1 and microRNA-133a expression are decreased during skeletal muscle hypertrophyQ28265961
AMP-activated protein kinase mediates myogenin expression and myogenesis via histone deacetylase 5Q28506793
Caffeine modulates phosphorylation of insulin receptor substrate-1 and impairs insulin signal transduction in rat skeletal muscleQ28573833
Profiles of connectin (titin) in atrophied soleus muscle induced by unloading of ratsQ28580947
Muscle-specific microRNA miR-206 promotes muscle differentiationQ30441356
FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70Q33589260
Changes in muscle mass and phenotype and the expression of autocrine and systemic growth factors by muscle in response to stretch and overloadQ33674248
Neuromuscular adaptation to microgravity environmentQ34052432
The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteinsQ34336799
Heat shock proteins: modifying factors in physiological stress responses and acquired thermotoleranceQ34605740
Response and function of skeletal muscle heat shock protein 70.Q36486672
AMP-activated protein kinase and the regulation of glucose transportQ36528251
Overexpression of inducible 70-kDa heat shock protein in mouse improves structural and functional recovery of skeletal muscles from atrophyQ36598830
Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy.Q36647399
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of NamptQ36728127
AMP-activated protein kinase α1 but not α2 catalytic subunit potentiates myogenin expression and myogenesisQ37336599
Hsp27 inhibits IKKbeta-induced NF-kappaB activity and skeletal muscle atrophyQ37355369
MicroRNAs in skeletal muscle: their role and regulation in development, disease and function.Q37781219
Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism.Q37808513
AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1.Q39456716
Possible Role of NF-ĸB Signals in Heat Stress-Associated Increase in Protein Content of Cultured C2C12 CellsQ39573043
AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubesQ40109932
AMP-activated protein kinase agonists increase mRNA content of the muscle-specific ubiquitin ligases MAFbx and MuRF1 in C2C12 cellsQ40177203
Coordinated maintenance of muscle cell size control by AMP-activated protein kinaseQ42164316
Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury modelQ42914173
AMPK inhibits myoblast differentiation through a PGC-1alpha-dependent mechanism.Q44948044
Overload induced heat shock proteins (HSPs), MAPK and miRNA (miR-1 and miR133a) response in insulin-resistant skeletal muscleQ45292348
P433issue3
P921main subjectskeletal muscle cellQ66505052
P304page(s)E344-54
P577publication date2013-12-17
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleAICAR-induced activation of AMPK negatively regulates myotube hypertrophy through the HSP72-mediated pathway in C2C12 skeletal muscle cells
P478volume306

Reverse relations

cites work (P2860)
Q59134223AMPK Mediates Muscle Mass Change But Not the Transition of Myosin Heavy Chain Isoforms during Unloading and Reloading of Skeletal Muscles in Mice
Q47781006AMPK in skeletal muscle function and metabolism.
Q57281692Activation of adiponectin receptors has negative impact on muscle mass in C2C12 myotubes and fast-type mouse skeletal muscle
Q38421077Comparative effects of whey protein versus L-leucine on skeletal muscle protein synthesis and markers of ribosome biogenesis following resistance exercise
Q38923257Concurrent exercise training: do opposites distract?
Q36902232Cytosolic calcium transients are a determinant of contraction-induced HSP72 transcription in single skeletal muscle fibers.
Q89661930Effects of tannase-converted green tea extract on skeletal muscle development
Q42515389FENOFIBRATE REVERSES CHANGES INDUCED BY HIGH-FAT DIET ON METABOLISM IN MICE MUSCLE AND VISCERAL ADIPOCYTES.
Q53121076Heat shock transcription factor 1-associated expression of slow myosin heavy chain in mouse soleus muscle in response to unloading with or without reloading.
Q57022882In vitro experimental models for examining the skeletal muscle cell biology of exercise: the possibilities, challenges and future developments
Q35784862Inducing Muscle Heat Shock Protein 70 Improves Insulin Sensitivity and Muscular Performance in Aged Mice
Q35874839Investigation of the Expression of Myogenic Transcription Factors, microRNAs and Muscle-Specific E3 Ubiquitin Ligases in the Medial Gastrocnemius and Soleus Muscles following Peripheral Nerve Injury
Q52926464Involvement of AMPK in regulating slow-twitch muscle atrophy during hindlimb unloading in mice
Q89702767Myostatin Increases Smad2 Phosphorylation and Atrogin-1 Expression in Chick Embryonic Myotubes
Q57476059The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration
Q37043350The serine protease, dipeptidyl peptidase IV as a myokine: dietary protein and exercise mimetics as a stimulus for transcription and release

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